Protein Alignment Gp150 and conv

DIOPT Version :10

• Sequence 1: NP_477049.2
• Gene: Gp150 / 37549
• FlyBaseID: FBgn0013272
• Length: 1076
• Species: Drosophila melanogaster
• Sequence 2: NP_610948.2
• Gene: conv / 36588
• FlyBaseID: FBgn0261269
• Length: 1092
• Species: Drosophila melanogaster
• Alignment Length: 848
• Identity: 195/848 - (22%)
• Similarity: 332/848 - (39%)
• Gaps: 190/848 - (22%)

  Fly   288 SDITDLVVTNVGPK-YPILMGPNFFQNLGLKNVASIKIANCTLEYLHAEAFHGLNELYAVNLTDV 351
            :|:|.|...||... ...|....|.:|..||   .:.:::..:..|.|.:|.|:..|..:.|:|.
  Fly   243 ADLTKLGWCNVSHNALSELSRGTFARNSVLK---VLHLSHNQIARLDANSFRGMRFLRRLFLSDN 304

  Fly   352 GLAIINPDTFVGNKKLRMLTISGN-----DLSVMSSIHYLLKSSSIEELDFSRNNLMELNPKAFS 411
            .|..|...||....::..:.::.|     :..:.:.::|      :|.||.:.||:.::...:|.
  Fly   305 VLTDIGRGTFGSIARIGTIDLARNRLKKIEFQMFTQMNY------VELLDLAENNITKIEKNSFK 363

  Fly   412 HLSNVVYINLSQNSLKKLPEKAFEKVTLLEELDLSYNSLTELPRDIFNGTTL-SILHLKYNTFNG 475
            .:...: ||:|.|:|:.:...|||....:..||||:|.|....|..|:.||. :...|.||....
  Fly   364 DIYQAI-INVSHNALELIETAAFENCVNITVLDLSHNRLANFSRRSFDETTFATYFQLSYNNLTN 427

  Fly   476 DLHFGTKD---LQQLDLSFNSIVQVHHSMFDKMPGLTNLNLKGNGIKKIQPDSFLTLKNLRHIDL 537
            ......::   |:.|:.|:|||.::..:.|.|:..|..:::..|.|..|....|.||.:||.|||
  Fly   428 LAQIPIQNMTGLKVLNASYNSITEIPKNCFPKLYELHTIDVSHNNISSIFNGVFQTLFSLRSIDL 492

  Fly   538 SINDLDQISGMLF----------FKNSEL-DVIR-------------LNDN--PRLSQLP---TD 573
            |.|.:.:|....|          ..::|| .|:|             ||:|  .:|.|||   .:
  Fly   493 SHNSMREIKSSTFGTLPTLLEMDLSHNELVSVVRGSLAKLTSLRQLYLNNNQLEKLFQLPISLNE 557

  Fly   574 GFLSY-------SGEFTV----YYLDISNCAIG-PLGHKAFSTMPHLTTLKLAWNNINHLPREIF 626
            .:.|:       ||.:.|    .|||:|:..:| .|..::|:.:..:..|||..|.|:..|::..
  Fly   558 LYFSHNRLTNIPSGTWPVMNSLIYLDLSHNQLGDTLNGESFTGLLVVQRLKLQNNGISQPPKDAV 622

  Fly   627 TGLHKLIDLDLSNNLITRMDDLIFMDNGELTKLSLAGNPISRLSVRLFLPLHQLRCLDVNDCELT 691
            ..:..|..|.|.||.||.::...|.....|.:|:|.||.:..:|.|.|..|.||..|:::...:.
  Fly   623 AVMSTLQYLHLENNNITTLERSAFGKLPVLFELNLYGNQVKDISKRAFEGLLQLLTLNLSSNGIQ 687

  Fly   692 TLLSDRDLGAGYKIFDSLRSFNASGNLIKKISSED---VKSFKNLRSLDITNNPL-----KCTPD 748
            ||.:|..:|     ..|||:.:.|.|.:.|:.::.   :....:|.:||:::|.:     |..|.
  Fly   688 TLQNDIFVG-----LPSLRNLDLSFNSLTKLDNKTNGVLDDLLSLETLDLSHNRISFVTKKTFPS 747

  Fly   749 FQEFISYVTLQMQMTPKRLPV-------------------------------------------- 769
            .| :|.|....:.::...:|:
  Fly   748 HQ-YIPYNLRNLNLSYNLMPILTYDITFGTKKLVRLDVSHNQINDLRRGVISNFTSLQSLDMSYN 811

  Fly   770 -LANLEDDATIVQLETLAQAGWSSLAHEVCKHAEGSDLLDEKK---ADSAEAKLEKRLKESVKKL 830
             |:||:.:..|..|.  ....|..|:|....|...::|:..|.   .|.....||......|..:
  Fly   812 ELSNLKSEEHIFDLP--QNLSWLDLSHNKIYHLPFANLVKVKSLKYVDLTNNSLEDVPASIVGSM 874

  Fly   831 NEDEAKLLS----------------VLDKSVLDKSRLSSMQKIMKGSVNTETAKPEEDADEENLN 879
            ......||:                :|.:::..:    .::.|..|:......|.....|:|.|:
  Fly   875 RNGSQVLLAGNPLHCGCNARPLKYFMLQQTIAGE----DLKSIYCGTPALIKDKQLISLDDEYLH 935

  Fly   880 NGGEDKEDDSSDYDSEEDDDDDDEDDDDDNNDDDRFEEAKKN----------AKAKADANKAFDT 934
                          ..||:.:..:..|.:...|.||.|.|.|          ....:|.:. |..
  Fly   936 --------------CAEDEQEMYKGIDYEQLTDVRFREVKTNKAGMLTLCWYVSGFSDVSD-FHV 985

  Fly   935 FVNKELKPVL---------KTDGIQAEEVDMSQETRDKFLLEKL-GFD--SESEESDEYTEKMIF 987
            ::......||         :|..|..||:....|       ||| |.:  ..|.:||..|.|. |
  Fly   986 YIRSSSNDVLHQSDYAYNNRTAQIPVEELSTLGE-------EKLRGAEICIVSRDSDGNTRKW-F 1042

  Fly   988 HGE 990
            .|:
  Fly  1043 SGQ 1045

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gp150	NP_477049.2	LRR	341..758	CDD:443914	127/474 (27%)
		leucine-rich repeat	343..366	CDD:275380	7/22 (32%)
		leucine-rich repeat	367..391	CDD:275380	2/28 (7%)
		leucine-rich repeat	393..415	CDD:275380	6/21 (29%)
		leucine-rich repeat	416..439	CDD:275380	8/22 (36%)
		leucine-rich repeat	440..483	CDD:275380	13/43 (30%)
		leucine-rich repeat	463..481	CDD:275380	3/18 (17%)
		leucine-rich repeat	484..507	CDD:275380	8/22 (36%)
		leucine-rich repeat	508..531	CDD:275380	7/22 (32%)
		leucine-rich repeat	532..569	CDD:275380	17/62 (27%)
		leucine-rich repeat	556..583	CDD:275380	13/52 (25%)
		leucine-rich repeat	570..607	CDD:275380	13/51 (25%)
		leucine-rich repeat	608..631	CDD:275380	6/22 (27%)
		leucine-rich repeat	632..655	CDD:275380	8/22 (36%)
		leucine-rich repeat	656..674	CDD:275380	7/17 (41%)
		leucine-rich repeat	733..745	CDD:275378	4/16 (25%)
conv	NP_610948.2	leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	150..175	CDD:275380
		leucine-rich repeat	176..199	CDD:275380
		PPP1R42	191..359	CDD:455733	28/124 (23%)
		LRR_8	198..258	CDD:404697	5/14 (36%)
		leucine-rich repeat	200..223	CDD:275380
		leucine-rich repeat	224..271	CDD:275380	8/27 (30%)
		leucine-rich repeat	272..295	CDD:275380	6/25 (24%)
		leucine-rich repeat	296..319	CDD:275380	7/22 (32%)
		leucine-rich repeat	322..343	CDD:275380	1/20 (5%)
		leucine-rich repeat	344..367	CDD:275380	6/22 (27%)
		LRR	346..718	CDD:443914	108/377 (29%)
		leucine-rich repeat	371..390	CDD:275380	7/18 (39%)
		leucine-rich repeat	391..414	CDD:275380	9/22 (41%)
		leucine-rich repeat	416..438	CDD:275380	3/21 (14%)
		leucine-rich repeat	439..462	CDD:275380	8/22 (36%)
		leucine-rich repeat	463..486	CDD:275380	7/22 (32%)
		leucine-rich repeat	487..510	CDD:275380	9/22 (41%)
		leucine-rich repeat	511..534	CDD:275380	4/22 (18%)
		leucine-rich repeat	535..554	CDD:275380	7/18 (39%)
		leucine-rich repeat	555..578	CDD:275380	4/22 (18%)
		leucine-rich repeat	579..603	CDD:275380	7/23 (30%)
		leucine-rich repeat	604..627	CDD:275380	6/22 (27%)
		leucine-rich repeat	628..649	CDD:275380	8/20 (40%)
		PPP1R42	631..849	CDD:455733	49/225 (22%)
		leucine-rich repeat	652..672	CDD:275380	8/19 (42%)
		leucine-rich repeat	700..726	CDD:275380	5/25 (20%)
		leucine-rich repeat	727..745	CDD:275380	5/17 (29%)
		leucine-rich repeat	779..802	CDD:275380	0/22 (0%)
		leucine-rich repeat	829..852	CDD:275380	5/22 (23%)