DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Gp150 and CG42346

DIOPT Version :10

Sequence 1:NP_477049.2 Gene:Gp150 / 37549 FlyBaseID:FBgn0013272 Length:1076 Species:Drosophila melanogaster
Sequence 2:NP_001036303.2 Gene:CG42346 / 3355160 FlyBaseID:FBgn0259677 Length:1817 Species:Drosophila melanogaster


Alignment Length:908 Identity:203/908 - (22%)
Similarity:351/908 - (38%) Gaps:220/908 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 SHSNTVGPKIHFIHDDLTENELNSGEEVSPTESLPKISTPKVKDLPVETTTRSPTKKTTSSGTEK 112
            |..||..|...|  :|....|......:|...:|.:||.| :..|.:....||.|          
  Fly   238 SFDNTACPCYKF--EDGLFLECPGTTAISLRSTLERISAP-IHSLSIYDFDRSVT---------- 289

  Fly   113 SLSEEAW------NDLMEAAKHSQALADDPHFNKMLNTTVAAGEKNSTDTDDSEYYDYDDDYNYF 171
            |||::.:      ..|..:..|.:||.|:                                    
  Fly   290 SLSQDVFQPGVHIRHLQFSHSHLEALKDN------------------------------------ 318

  Fly   172 DEETVTISPSPKKAKSNPKLQPIVDATITKSKSKSNDQKTKESANDIDSDSQYDYDE-------- 228
                     |.:..:|:.:...||:..:|:..|::.....|.:|.|      :||:|        
  Fly   319 ---------SLRNVRSSLESLSIVNGKLTQMPSRALSSMQKLTALD------FDYNEIVRVDDYS 368

  Fly   229 -------------------------GLDDDDDEDDAADDLL----------TDDEQVVFSEDVPC 258
                                     ||::...|.|.:::.|          .|..:::...:...
  Fly   369 FYGLRISKLNMKGNRLQGMPEHAFAGLEECMQEIDVSENGLRTFPLMALRKLDHLRILRLSNNRI 433

  Fly   259 PRF---CQCARN--------VNSYLVATCSRLDMGIQKFGSDITDLVVTNVGP----KYPILMGP 308
            |.|   .|.|.|        |.::.:.:...||:...:|         ..:||    .:|.|...
  Fly   434 PTFYGDIQLATNNASAAAAAVGAFQLPSLIFLDLSSNQF---------AEIGPDCFRAFPQLKTL 489

  Fly   309 NFFQNLGLKNVASIKIANCTLEYLHAEAFHGLNELYAVNLTDVGLAIINPDTFVGNKKLRMLTIS 373
            :|:.|              .:|.:..|||..|.||.:::::...:..::|..|..||:|:.:.:|
  Fly   490 SFYAN--------------QIELVQPEAFKSLRELMSLDMSHNRIIGLDPKVFEKNKRLQTVDLS 540

  Fly   374 GNDLSVMSSIHYLLKSSSIEELDFSRNNLMELNPKAFSHLSNVVYINLSQNSLKKLPEKAFEKVT 438
            .|.:..:..:...|  ..:.|:..|.||::||...||::.:||..|.|..|::..:....|..:.
  Fly   541 HNHIHTIGGVFSNL--PQLREVFLSENNILELPADAFTNSTNVDVIYLESNAIAHIDPNVFSTLV 603

  Fly   439 LLEELDLSYNSLTELPRDIFN-GTTLSILHLKYNTFNGDLHFG----TKDLQQLDLSFNSIVQVH 498
            .|:.|.|..|.:..||..:|: .|.|:.|.|..|... ||..|    .:.|:::.|..|.|.:|.
  Fly   604 NLDHLYLRSNFIPLLPVTLFDKSTKLTSLSLDNNEIQ-DLEIGMFRKLEHLREVRLHNNRIRRVR 667

  Fly   499 HSMFDKMPGLTNLNLKGNGIKKIQPDSFLTLKNLRHIDLSINDLDQISGMLFFKNSELDVIRLND 563
            ..:|:.:|.|..|:::.|.|:.|:|.:|.||:|::||:|..|.|..:..:...:||.|..::|..
  Fly   668 RGVFEPLPSLQELHIQKNSIEDIEPQAFHTLENMQHINLQDNQLTVLEDIFPDENSSLLSVQLEA 732

  Fly   564 N------PRLSQLPTDGFLSYSGEFTVYYLDISNCAIGPLGHKAFSTMPHLTTLKLAWNNINHLP 622
            |      ||          ::|.:..|..:.:.:..:..:....|:..|.|..|.|:.|.|..:.
  Fly   733 NYLHKVHPR----------TFSRQQKVQIMWLKDNQLTRVERSFFADTPQLGRLYLSDNKIRDIE 787

  Fly   623 REIFTGLHKLIDLDLSNNLITRMDDLIFMDNGELTKLSLAGNPISRLSVRLFLPLHQLRCLDVND 687
            ::.|..|..|..||||.|.:.::....|....:|.:||||.|.|..:....|..|..|:.||::.
  Fly   788 KDTFVNLLLLQFLDLSGNQLRQLRRDYFAPLQDLEELSLARNHIEAIEGYAFAKLKNLKSLDLSH 852

  Fly   688 CELTTLLSDRDLGAGYKIFDS---LRSFNASGNLIKKISSEDVKSFKNLRSLDITNNPLKCTPDF 749
            ..|..|..|        ||.:   |.|.|.....::|:.....||..||..|::..|.|. ..|.
  Fly   853 NPLVQLTRD--------IFSNEFPLNSLNLGNCSLRKLEQHAFKSLTNLNELNLERNQLN-PADI 908

  Fly   750 QEFISYVTLQMQMTPKRL------------PVLANLEDDATIVQLETLAQAGWSSLAHEVCKHAE 802
            |      ||.:....:.|            .::|.:.|     :|.:|.|...|:     |...:
  Fly   909 Q------TLDIPNLRRLLLSHNNFSYAGSVGIMAGMLD-----RLRSLQQLSMSN-----CSLGQ 957

  Fly   803 GSDLLDEKKADSAEAKL-EKRLKESVKKLNEDEAKLLSVLDKSVLDKSRLSSMQKIMKGSVNT 864
            ..|||..|..:.....| :.||.:    :|.:....|:|..:..|.::.||....|...:::|
  Fly   958 IPDLLFAKNTNLVRLDLCDNRLTQ----INRNIFSGLNVFKELRLCRNELSDFPHIALYNLST 1016

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gp150NP_477049.2 LRR 341..758 CDD:443914 116/430 (27%)
leucine-rich repeat 343..366 CDD:275380 4/22 (18%)
leucine-rich repeat 367..391 CDD:275380 4/23 (17%)
leucine-rich repeat 393..415 CDD:275380 8/21 (38%)
leucine-rich repeat 416..439 CDD:275380 5/22 (23%)
leucine-rich repeat 440..483 CDD:275380 15/47 (32%)
leucine-rich repeat 463..481 CDD:275380 7/21 (33%)
leucine-rich repeat 484..507 CDD:275380 6/22 (27%)
leucine-rich repeat 508..531 CDD:275380 9/22 (41%)
leucine-rich repeat 532..569 CDD:275380 12/42 (29%)
leucine-rich repeat 556..583 CDD:275380 6/32 (19%)
leucine-rich repeat 570..607 CDD:275380 3/36 (8%)
leucine-rich repeat 608..631 CDD:275380 7/22 (32%)
leucine-rich repeat 632..655 CDD:275380 7/22 (32%)
leucine-rich repeat 656..674 CDD:275380 7/17 (41%)
leucine-rich repeat 733..745 CDD:275378 4/11 (36%)
CG42346NP_001036303.2 LRR <301..606 CDD:443914 67/380 (18%)
leucine-rich repeat 303..325 CDD:275380 6/66 (9%)
leucine-rich repeat 327..350 CDD:275380 4/22 (18%)
leucine-rich repeat 351..461 CDD:275380 17/115 (15%)
leucine-rich repeat 399..422 CDD:275380 3/22 (14%)
leucine-rich repeat 462..485 CDD:275380 5/31 (16%)
LRR 486..>736 CDD:443914 74/266 (28%)
leucine-rich repeat 486..509 CDD:275380 8/36 (22%)
leucine-rich repeat 510..533 CDD:275380 4/22 (18%)
leucine-rich repeat 534..556 CDD:275380 4/23 (17%)
leucine-rich repeat 557..580 CDD:275380 8/22 (36%)
leucine-rich repeat 581..604 CDD:275380 5/22 (23%)
leucine-rich repeat 605..628 CDD:275380 7/22 (32%)
PPP1R42 627..860 CDD:455733 69/243 (28%)
leucine-rich repeat 629..652 CDD:275380 7/23 (30%)
leucine-rich repeat 653..676 CDD:275380 6/22 (27%)
leucine-rich repeat 677..700 CDD:275380 9/22 (41%)
leucine-rich repeat 701..748 CDD:275380 13/56 (23%)
leucine-rich repeat 725..736 CDD:275378 3/10 (30%)
leucine-rich repeat 749..772 CDD:275380 2/22 (9%)
leucine-rich repeat 773..793 CDD:275380 6/19 (32%)
leucine-rich repeat 821..844 CDD:275380 9/22 (41%)
leucine-rich repeat 845..868 CDD:275380 8/30 (27%)
LRR 869..1226 CDD:443914 38/169 (22%)
leucine-rich repeat 869..892 CDD:275380 6/22 (27%)
leucine-rich repeat 893..915 CDD:275380 8/28 (29%)
leucine-rich repeat 916..944 CDD:275380 4/32 (13%)
leucine-rich repeat 945..968 CDD:275380 8/27 (30%)
leucine-rich repeat 969..992 CDD:275380 5/26 (19%)
leucine-rich repeat 993..1014 CDD:275380 4/20 (20%)
leucine-rich repeat 1017..1040 CDD:275380 203/908 (22%)
leucine-rich repeat 1041..1064 CDD:275380
leucine-rich repeat 1089..1114 CDD:275380
leucine-rich repeat 1115..1162 CDD:275380
PPP1R42 1155..1317 CDD:455733
leucine-rich repeat 1163..1186 CDD:275380
leucine-rich repeat 1187..1210 CDD:275380
leucine-rich repeat 1211..1233 CDD:275380
leucine-rich repeat 1234..1257 CDD:275380
leucine-rich repeat 1258..1279 CDD:275380
leucine-rich repeat 1282..1306 CDD:275380
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.