DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5819 and LOC3290298

DIOPT Version :10

Sequence 1:NP_611660.1 Gene:CG5819 / 37547 FlyBaseID:FBgn0034717 Length:915 Species:Drosophila melanogaster
Sequence 2:XP_061503045.1 Gene:LOC3290298 / 3290298 VectorBaseID:AGAMI1_009617 Length:1207 Species:Anopheles gambiae


Alignment Length:500 Identity:140/500 - (28%)
Similarity:218/500 - (43%) Gaps:84/500 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    32 VVDSLYADCSRRSLQTYPNFDG-IPVEHLDLSGNKFLEF-PTLYADIDSLIYLDLSSNYISSIGA 94
            ::|.||...:.....|..:|.| :.:::|.|..|:.... |..:|.:.:|.||.|.||.::|:..
Mosquito   205 ILDELYLSFNFLERLTRNSFKGLVELDNLALHNNRISTIEPDTFASLATLQYLTLGSNRLTSLAP 269

  Fly    95 KTLIGFTSLRTLLLANNSIDSWESLSPNEAFKYAPSLKRLGLDGNRLGS-----FGNGESFELLT 154
            :|.|..|.|..|.|:.|.:    :..|.:.|:|..:||.|.:..|.|..     |.|        
Mosquito   270 ETFIAQTKLAKLDLSVNQL----AELPKDLFRYTTALKELKMSNNSLKELHSDLFAN-------- 322

  Fly   155 SSSLTDLGLSSCGISSIGGDQMVNQLPNLERLNLANNQLAQIAALPS-----RTLRVLDLSNCSI 214
            ::.|.||.:|...:.|:.. .:...|..||.|.|.||.:..|  .|.     ::||.|||:...|
Mosquito   323 TAKLEDLVISHNEVESLDA-ALFRNLRKLEMLLLENNNIGHI--FPGTFDALQSLRALDLNQNGI 384

  Fly   215 KNLSGFFLDAMQNLEALNLSRN----------------TELQFD-----SLSEDPILTYMLRKLD 258
            ..:.|....|::.|:.|.|..|                |||..:     |:.:|.:....|..|.
Mosquito   385 MTIEGGLFRALRVLDKLYLQNNLISMVSGDSLEGAVQLTELYLNKNPLQSIDDDFLRIPSLMALA 449

  Fly   259 VSYCNLDSIELSGL----PQLTEVRLQGNLLRVVDVNTFANNSMLEVVDLSQNVLRHIGQDAFAK 319
            :.:|.|.::. .||    ..|..:.|:||.|..:|.:.||....||.:|||.|:|.:| .:|.|.
Mosquito   450 MDFCGLKTLP-KGLFAKQQSLKLLFLEGNKLTDLDPDLFAPLVELEELDLSANLLYNI-SNALAN 512

  Fly   320 LKRLKELNLAFNEIARLDRNFIRNNDVLVELNLSRNVLQKLTKIVSNSVRTINMS--WCEITSIE 382
            |..||.|:|:.|.:..|..|...|...|.:|||.:|   |||:|.....:..|:|  ..|...|:
Mosquito   513 LTSLKLLDLSDNRLRSLQDNAFANMTTLKKLNLKQN---KLTEIPRALAKLPNLSTLTLETNKIK 574

  Fly   383 STALSS-LSVIQKLDLSNNLIT-----DMP------------------TFMRSETLQQLNLANCR 423
            ||.:.. |:.::.|.:..|.||     |.|                  ||:.:..|:.::|.:.|
Mosquito   575 STVVGEPLANLEDLYMGENEITKLRLNDFPAVEELYVERNQIHSLSVDTFVGNRKLKTVDLTDNR 639

  Fly   424 LTTVRNNTFREFPELADLHLNGNRLTSPIPPNYFDGNKFLDQLWL 468
            ||......|....:|..|.|:||.| ..:....|:|...|:.|.|
Mosquito   640 LTGPLEGIFTPLRKLVTLTLSGNPL-GRVTRATFEGLLKLEDLTL 683

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5819NP_611660.1 RNA1 <56..193 CDD:444072 41/142 (29%)
leucine-rich repeat 56..78 CDD:275380 5/22 (23%)
leucine-rich repeat 79..102 CDD:275380 9/22 (41%)
leucine-rich repeat 103..130 CDD:275380 7/26 (27%)
leucine-rich repeat 131..155 CDD:275380 7/28 (25%)
LRR 134..>466 CDD:443914 108/392 (28%)
leucine-rich repeat 158..182 CDD:275380 6/23 (26%)
leucine-rich repeat 204..227 CDD:275380 8/22 (36%)
leucine-rich repeat 254..274 CDD:275380 6/23 (26%)
leucine-rich repeat 275..298 CDD:275380 8/22 (36%)
leucine-rich repeat 299..322 CDD:275380 11/22 (50%)
leucine-rich repeat 323..346 CDD:275380 8/22 (36%)
leucine-rich repeat 347..391 CDD:275380 16/46 (35%)
leucine-rich repeat 392..413 CDD:275380 8/43 (19%)
leucine-rich repeat 414..437 CDD:275380 6/22 (27%)
LRRCT 471..517 CDD:214507
LOC3290298XP_061503045.1 None
Blue background indicates that the domain is not in the aligned region.

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