Protein Alignment Oatp58Db and slco5a1a

DIOPT Version :10

• Sequence 1: NP_611658.3
• Gene: Oatp58Db / 37544
• FlyBaseID: FBgn0034715
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: XP_073776477.1
• Gene: slco5a1a / 570033
• ZFINID: ZDB-GENE-090316-1
• Length: 819
• Species: Danio rerio
• Alignment Length: 741
• Identity: 205/741 - (27%)
• Similarity: 336/741 - (45%)
• Gaps: 135/741 - (18%)

  Fly     7 EASKFLKDKEAGINVADDEKRLNSSDTT----------CGFSI------------FRGP--ALQR 47
            |:::.||.|...: :::.:.....:|.|          ||..:            ||.|  .|:|
Zfish    26 ESTQGLKSKSLPV-LSESQTPERDADQTLLPAPHSSARCGSPVRTESREPEGVLRFRLPRLPLRR 89

  Fly    48 FATAHMFVIVYGI---ASCFL-----------AMAFTYFTGTITTMEKRFNIPTKISGLITVGND 98
            :        |.||   :.|||           .|...|.:..|||:|||:::.:..|||:....|
Zfish    90 Y--------VDGILADSRCFLFCMCYLTFIQSLMVSGYLSSVITTIEKRYSLRSSESGLLVSCFD 146

  Fly    99 ISTVFSSAFLSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEYGMSESFGA 163
            |.::....|:||:..||.||||:|:|.:.||:...|...||....|          |.:.|
Zfish   147 IGSLIVVVFISYFGGRGQRPRWLAVGGVFIAVGAALFSLPHFISPP----------YQLEE---- 197

  Fly   164 SLNITEKNDSLCHEKNSNCLERAGDYTP-----------------IVLFFIAQFIGGIGCSLFYA 211
             ||.|...:.||...:::. ..:|...|                 :.||..||.:.|:|.:..|.
Zfish   198 -LNSTVGGEGLCAGASASA-NASGQEKPTLSRCQREQEESEHALYVALFICAQILVGMGSTPIYT 260

  Fly   212 PGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGFSMVSLCLRLYIDPFKKPLITTNDPRWMGAWW 276
            .|.:|:|||.........|:....:..||||.|:.:..:.:..|:||.....|...|||::|.||
Zfish   261 LGPTYLDDNVKKENASLYLAIMYVMGALGPAAGYLLGGILIGFYVDPGTVVNIDQGDPRFVGNWW 325

  Fly   277 IGWIL--LTFILTISAVFVGMFPKEMP--RAKARRLKADGEEDIPL-----------------AG 320
            .|::|  :..:|.|..:|  .|||::|  :.|::|....|..|:..                 .|
Zfish   326 SGFLLCAVAMLLVIFPMF--SFPKKLPPRQKKSKRGVKKGAGDVSSDDEMMKEKSQAVSSSMGFG 388

  Fly   321 RSFQDMLDSLKRLASNKVYVYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALG 385
            ::.:|:..:..|:.||..:::..|:..........:..|.||:||.|:...||::::.||...:.
Zfish   389 KNIKDLPKAAVRILSNVTFLFVSLSYTAECAIVTAFITFIPKFIESQFGVPASSASIYTGLIIVP 453

  Fly   386 FSAAGILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCY---VLVGCDESDRANSLSI-VPTG 446
            .:..||.:.||:|.|.|..||..|....:...::   :||:   .:||| ||.....::| ..||
Zfish   454 SAGVGIFLGGYIIKKLKLGAREAAKLAMICSGVS---LLCFSTLFIVGC-ESINLGGINIPYTTG 514

  Fly   447 -----------DSCSASCVCEYVYYAPVCSPENITFISACHAGCTDKAINELGKTIYTGCRCMGN 500
                       .||:.:|.|:...|||||..:.||:.:.|.|||::.|.:..|...|:.|.|:.:
Zfish   515 PTLTLSHRNLTGSCNVNCGCKIHEYAPVCGSDGITYFNPCLAGCSNIANHTSGIRNYSDCACVQS 579

  Fly   501 VSSI--------ISLSNVTSLASQSQIAMDGACPVDCNK--QFLIFLAVMCFLKFVGATGRSSNL 555
            ...|        :.|..|.:..:::..|:.|.|...|..  .|||||.:   :..:.|..:.|.:
Zfish   580 RQVITPSGGNHELQLVIVKTYLNENGFALAGKCERTCGTLITFLIFLFI---VTLITACAQPSVI 641

  Fly   556 LLALRCVPSKDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWGKTCSSKGNCWIYDTKSLR 620
            ::.||.|..:|:.|:||...::...||:||:||.||.::|:.|::|.:.|...|:||.||..|||
Zfish   642 IVTLRSVDEEDRPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQDCGFHGSCWEYDVTSLR 706

  Fly   621 YTMNLVCASLIFLGSFWNIGVWYHAK 646
            :....:.|||.|||..:....||..|
Zfish   707 FVYFGLAASLKFLGFLFIFLTWYSLK 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Db	NP_611658.3	OATP	53..619	CDD:460821	180/642 (28%)
slco5a1a	XP_073776477.1	None