DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ari-2 and ARI9

DIOPT Version :9

Sequence 1:	NP_477374.1	Gene:	ari-2 / 37542	FlyBaseID:	FBgn0025186	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_180736.1	Gene:	ARI9 / 817734	AraportID:	AT2G31770	Length:	543	Species:	Arabidopsis thaliana

Alignment Length:	516	Identity:	151/516 - (29%)
Similarity:	238/516 - (46%)	Gaps:	57/516 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DMESDNDGEYDDDYDYYNTGEDCD----VERLDPKRADPEYFEYECLTVEDIEKLLNERVEKLNT 68
            ||..:..||  ::|.|....|..|    |:.:.|...     .|..|..|||.||..:.:|::::
plant     7 DMIDNKSGE--ENYSYGGGNESDDYNDVVDTIIPSEK-----SYVILKEEDILKLQRDDIERVSS 64

  Fly    69 ILQITPSLAKVLLLEHQWNNVAVVEKYRQDANAL-LVTARIKPPSVAVTDTASTSAAAASAQLLR 132
            ||.::.....||||.:.|....|.:::..|...: .....:|.|.|...
plant    65 ILSLSQVEVIVLLLHYNWCVSKVEDEWFTDEERIRKAVGLLKEPVVDFN---------------- 113

  Fly   133 LGSSGYKTTASATPQYRSQMCPVCASSQLGDKFYSLACGHSFCKDCWTIYFETQIFQGIS-TQIG 196
             |....|.......|     |.:|..|...::...::|||.:||.||..|..|:|..|.. .::.
plant   114 -GGEKDKKCRKVNIQ-----CGICFESYTREEIARVSCGHPYCKTCWAGYITTKIEDGPGCLRVK 172

  Fly   197 CMAQMCNVRVPEDLVLTLVTRPVMRDKYQQFAFKDYVKSHPELRFCPGPNCQIIVQ--SSEISAK 259
            |....|:..|.:|::.. ||...:.:||.::..:.||:...::::||.|.|...|:  .||.|:.
plant   173 CPEPSCSAAVGKDMIED-VTETKVNEKYSRYILRSYVEDGKKIKWCPSPGCGYAVEFGGSESSSY 236

  Fly   260 RAICKACHTGFCFRCGMDYHAPTDCQVIKKWLTKCADDSETANYISAHTKDCPKCHICIEKNGGC 324
            ...| .|...||:.|..|.|:|.||..:.||:.|..|:||..|::.|::|.||:|...||||.||
plant   237 DVSC-LCSYRFCWNCSEDAHSPVDCDTVSKWIFKNQDESENKNWMLANSKPCPECKRPIEKNDGC 300

  Fly   325 NHMQC-FNCKHDFCWMCLGDWKTHGSEYYECSRYKDNPNIANESVHVQAREALKKYLHYYERW-E 387
            |||.| ..|.|:|||:||..::.|..   .|:|:...   ..||.....:..:|:|.|||.|| |
plant   301 NHMTCSAPCGHEFCWICLKAYRRHSG---ACNRFVVE---QAESKRALLQSEIKRYTHYYVRWAE 359

  Fly   388 NHSKSLKLEQQTIDRLRQRINSKVMNGSGTWIDWQYLFNAAALL--AKCRYTLQYTYPYAYYMEA 450
            |.|..|| ..:.:::| |.:..|.::.:....:.|..|...|.|  .:||..|::||.|.||::.
plant   360 NQSSRLK-AMRDLEKL-QSVQLKELSDNQCTSETQLQFTVDAWLQIIECRRVLKWTYAYGYYLQD 422

  Fly   451 GSRKNLFEYQQAQLEAEIENLSWKIER------AETTDLGDLENQMDIAEKRRTTLLKDFF 505
            ..::..|||.|.:.|:.:|.|....|.      .::.|..|..|...:.....||:.|.:|
plant   423 LPKRKFFEYLQGEAESGLERLHHCAENELKQFFIKSEDPSDTFNAFRMKLTGLTTVTKTYF 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-2	NP_477374.1	RING-HC_RBR_TRIAD1	151..204	CDD:319687	16/53 (30%)
ari-2	NP_477374.1	IBR	222..284	CDD:214763	20/63 (32%)
ARI9	NP_180736.1	RING-HC_RBR_TRIAD1_like	128..178	CDD:319537	15/49 (31%)
		IBR	197..260	CDD:214763	20/63 (32%)
		IBR	<282..326	CDD:396187	23/43 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3648
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54219
OrthoDB	1	1.010	-	-		D469819at2759
OrthoFinder	1	1.000	-	-		FOG0000379
OrthoInspector	1	1.000	-	-		mtm1045
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.890