Protein Alignment ari-2 and Rnf217

DIOPT Version :10

• Sequence 1: NP_477374.1
• Gene: ari-2 / 37542
• FlyBaseID: FBgn0025186
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001139821.1
• Gene: Rnf217 / 268291
• MGIID: 3610311
• Length: 515
• Species: Mus musculus
• Alignment Length: 230
• Identity: 60/230 - (26%)
• Similarity: 90/230 - (39%)
• Gaps: 47/230 - (20%)

  Fly   152 MCPVCASSQLGDKFYS--LACGHSFCKDCWTIYFETQIFQGISTQIGCMAQMCNVRVPEDLVLTL 214
            ||.||    |.||...  ..|..:.|::|..||..:|:..| ..:|.|....|...:.|..|:..
Mouse   235 MCRVC----LEDKPIKPLPCCKKAVCEECLKIYLSSQVQLG-QVEIKCPVTECFEFLEETTVVYN 294

  Fly   215 VTRPVMRD--KYQQFAFKDYVKSHPELRFCPGPNCQ----------IIVQSSEISAKRAICKACH 267
            :|.   .|  ||:.|.....:.|..:    |.|.|:          |...|...|..:..|..|.
Mouse   295 LTH---EDSIKYKYFLELGRIDSSTK----PCPQCKHFTTFKKKGHIPTPSRSESRYKIQCPTCQ 352

  Fly   268 TGFCFRCGMDYHAPTDCQVIKK-------WLTKCADDSETANYISAHTKDCPKCHICIEKNGGCN 325
            ..:||:|...:|...:|:..||       |.::.......|       :.||||.|.|::..||:
Mouse   353 LIWCFKCHSPWHEGVNCKEYKKGDKLLRHWASEIEHGQRNA-------QKCPKCKIHIQRTEGCD 410

  Fly   326 HMQCFNCKHDFCWMCLGDWKTHGSEYYECSRYKDN 360
            ||.|..|..:||:.|       |..|.:...:.|:
Mouse   411 HMTCSQCNTNFCYRC-------GERYRQLRFFGDH 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ari-2	NP_477374.1	RING-HC_RBR_TRIAD1	152..204	CDD:438429	17/53 (32%)
		BRcat_RBR_TRIAD1	231..302	CDD:439005	17/87 (20%)
		Rcat_RBR_TRIAD1	306..361	CDD:439021	18/55 (33%)
		Ariadne	371..>477	CDD:466073
Rnf217	NP_001139821.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..125
		PHA03307	<25..>141	CDD:223039
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..189
		TRIAD supradomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU01221	232..451		60/230 (26%)
		vRING-HC-C4C4_RBR_RNF217	234..282	CDD:438284	16/51 (31%)
		BRcat_RBR_RNF217	311..385	CDD:439003	17/77 (22%)
		Rcat_RBR_RNF217	389..456	CDD:439011	19/64 (30%)