DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ari-2 and C17H11.6

DIOPT Version :9

Sequence 1:	NP_477374.1	Gene:	ari-2 / 37542	FlyBaseID:	FBgn0025186	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_001123112.1	Gene:	C17H11.6 / 181076	WormBaseID:	WBGene00015926	Length:	893	Species:	Caenorhabditis elegans

Alignment Length:	312	Identity:	72/312 - (23%)
Similarity:	122/312 - (39%)	Gaps:	82/312 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 DANALLVTARIKPPSVAVTDTASTSAAAASAQLLRLGSSGYKTTASA------------------ 144
            |.||    ..:...||:.:|..|..:.:.|::..|...:|....:.|
Worm   108 DDNA----GHVAMTSVSSSDVRSNVSGSISSKRYRGSDTGSGMDSEAGETCAEMLLSSRNQDDEE 168

  Fly   145 -------------TPQYRSQM----------CPVCASSQLGDKFYSL-ACGHSFCKDCWTIYFET 185
                         ||:..|::          ||:||:...|..|..| .|.|..|:.|...|.|.
Worm   169 QSDEKQLSQSLPDTPKTPSEVGKKGKGKMKECPLCAAKMPGSAFPKLKGCQHRSCRACLRQYVEL 233

  Fly   186 QIFQGISTQIGCMAQMCNVRVPEDLVLTLVTRPVMRDKYQQFAFKDYVKSHPELRFCPGPNCQII 250
            .|.:. ..::.| .:..:...|.|:.:.:...|.:.:||:.|:.:.|:.:..:.|:||.|:|..:
Worm   234 SITEN-RVEVPC-PECSSYLHPNDIKMLIGDIPTLIEKYEAFSLRRYLMTEADARWCPAPDCGFV 296

  Fly   251 VQSSEISAKRAICKA-------CHTGFCFRCGMDYHAPTDC-----------------QVIKKWL 291
            .    |:.|.|.|..       |.|.||:.|..::|:...|                 ::::...
Worm   297 F----IATKCAACPQLKCQRPDCGTLFCYHCKREWHSNQTCDEARRPEKRKSRGLAFEEIMRTGF 357

  Fly   292 TKCADDSETANYISAHTKDCPKCHICIEK--NGGCNHMQCFNCKHDFCWMCL 341
            .:.||.:.....:.|    ||:|...|.|  :|.||||.|..|..:|||:||
Worm   358 HQSADSTLKPGDVKA----CPRCKTYIVKMDDGSCNHMVCTMCNAEFCWLCL 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ari-2	NP_477374.1	RING-HC_RBR_TRIAD1	151..204	CDD:319687	15/63 (24%)
ari-2	NP_477374.1	IBR	222..284	CDD:214763	19/68 (28%)
C17H11.6	NP_001123112.1	IBR	268..333	CDD:214763	19/68 (28%)
		IBR	<369..407	CDD:279784	18/41 (44%)
		AzlC	<433..529	CDD:294385
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910