Protein Alignment LBR and Dhcr7

DIOPT Version :10

• Sequence 1: NP_726114.1
• Gene: LBR / 37482
• FlyBaseID: FBgn0034657
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: NP_071784.1
• Gene: Dhcr7 / 64191
• RGDID: 621769
• Length: 471
• Species: Rattus norvegicus
• Alignment Length: 506
• Identity: 123/506 - (24%)
• Similarity: 189/506 - (37%)
• Gaps: 142/506 - (28%)

  Fly   311 W--LGAFLFLLLL-PTAVYYLTWSCTARNACQFKHLNLGI------LLDVNYLTRQVF--QPRVV 364
            |  |.:.:||||. |..|||...:|. :.:|......|.:      |.|:...|..|.  ..::.
  Rat    33 WFSLVSVIFLLLFAPFIVYYFIMACD-QYSCSLTAPILDVATGRASLADIWAKTPPVTAKAAQLY 96

  Fly   365 GAFAAYQVVVFLLV-----ALLPGRRVHLTRETYKFNCLAVSLTLLIASGVAEYLKYPV---VTF 421
            ..:.::||:::..:     ..|||         |.......::|   .:|:..  ||.|   ..:
  Rat    97 ALWVSFQVLLYSWLPDFCHRFLPG---------YVGGVQEGAIT---PAGIVN--KYEVNGLQAW 147

  Fly   422 VLRHYLRFCIFGLVGAFVAAAWS-----------YWLVDTAKYNV---------LRQTLTNDYGR 466
            ::.|:|.|     |.|::.:.:|           .|..:...|.|         |..|...|...
  Rat   148 LITHFLWF-----VNAYLLSWFSPTIIFDNWIPLLWCANILGYAVSTFAMIKGYLFPTSAEDCKF 207

  Fly   467 TGSFVVDFALGRQLNP---KWLGRVDWKQ-FQYRLSLVT-TLIYATCYIYQTLVWPQKPQLGEQE 526
            ||:|..::.:|.:.||   ||.   |:|. |..|..:|. |||        .|.:..|.|  |..
  Rat   208 TGNFFYNYMMGIEFNPRIGKWF---DFKLFFNGRPGIVAWTLI--------NLSFAAKQQ--ELY 259

  Fly   527 GYLYQAKYYWNNVNYDPATLFSASCLLFYVLDAIIFEHHLSSSFELQHEGYG-------CLLLLR 584
            |::..:....|.:.            ..||||....|.....:.::.|:.:|       |:.|
  Rat   260 GHVTNSMILVNVLQ------------AIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWL-- 310

  Fly   585 YAATPYLLTAVTKYFYEQRVPISCWYAPLAVAALLSLGLLVKRFSCAYKYKYRL-NSQSPIFAN- 647
                |||.|....|.....|.:|   .|.|:..|| |||:      .| |.:|: |.|..:|..
  Rat   311 ----PYLYTLQGLYLVYHPVQLS---TPNALGVLL-LGLV------GY-YIFRMTNHQKDLFRRT 360

  Fly   648 -------------IETIHT-----YQGSRLLLSGMWGWVRQPNYLGDIVALLALAAPMA----LR 690
                         ||..:|     ...|:||:||.||..|..||.||::..||......    |
  Rat   361 DGHCLIWGKKPKAIECSYTSADGLKHRSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLL- 424

  Fly   691 PAWPPVLGLSLIILLLLHRATRANARNQARYHSSWQRYSTQVRSYILPRVY 741
                |...:..:.:||.||..|...|...:|...|:||...|...:||.::
  Rat   425 ----PYFYIIYMTILLTHRCLRDEHRCANKYGRDWERYVAAVPYRLLPGIF 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBR	NP_726114.1	ICMT	304..741	CDD:473892	123/504 (24%)
Dhcr7	NP_071784.1	ICMT	89..471	CDD:473892	106/447 (24%)