Protein Alignment LBR and tm7sf2

DIOPT Version :10

• Sequence 1: NP_726114.1
• Gene: LBR / 37482
• FlyBaseID: FBgn0034657
• Length: 741
• Species: Drosophila melanogaster
• Sequence 2: XP_031755653.1
• Gene: tm7sf2 / 100127815
• XenbaseID: XB-GENE-1005373
• Length: 467
• Species: Xenopus tropicalis
• Alignment Length: 522
• Identity: 143/522 - (27%)
• Similarity: 233/522 - (44%)
• Gaps: 91/522 - (17%)

  Fly   243 SRYSRSVSRSVYDDEKSSKRSYSTGE------EDIDEEDELEEDQFRSFNVTRKSATPAEISCRQ 301
            |.:.:|.|..|.  |..|:|..:.|.      |::...|::            |::..:|:
 Frog    14 SFWKKSCSTCVL--EWGSRRCRNHGRLSNYLVEELKMADKI------------KTSRTSEL---- 60

  Fly   302 LKAPREFGGWLGAFLFLLLLPTAVYYLTWSCTARNACQFKHLNLGILLDVNYLTRQVFQPRVVGA 366
                 ||||.|||.|.|.::|..|.||..:|:..:|...:.......||..:   ..|...::.:
 Frog    61 -----EFGGPLGALLLLFVMPGTVLYLLVTCSTEDASVLRVPGPWPALDTLW---DPFAVILLLS 117

  Fly   367 FAAYQVVVFLLVALLPGRRVHL---TRETYKFNCL-AVSLTLLIASGVAEYLKYPVVTFVLRHYL 427
            :.:.|.|:::|........:.|   ||..|:.|.| |:.:|.|||:| |....:| :::|..|:|
 Frog   118 WVSLQAVLYMLPIGKVTEGITLRDNTRLKYRINALQAMMVTALIAAG-AVMFGFP-LSYVYDHFL 180

  Fly   428 RFCIFGLVGAFVAAAWSYWLVDTAKYNVLRQTLTNDYGRTGSFVVDFALGRQLNPKWLGRVDWKQ 492
            :..:   ..||:|...|.:|.  ||.....|:.....|.:|:.:.||.:|.:|||: :|..|.|.
 Frog   181 QMAV---GAAFIALILSIFLY--AKSLAAPQSALAPGGNSGNPLYDFFIGHELNPR-IGSFDLKY 239

  Fly   493 F-QYRLSLVTTLIYATCYIYQTLVWPQKPQLGEQEGYLYQAKYYWNNVNYDPATLFSASCLLFYV 556
            | :.|..|:...:...|::.:.:.....|.|.....:.:||                     .||
 Frog   240 FCELRPGLIGWCLINLCFLMKDIELRGSPSLSMILVFGFQA---------------------LYV 283

  Fly   557 LDAIIFEHHLSSSFELQHEGYGCLLL---LRYAATPYLLTAVTKYFYEQRVPISCWYAPLAVAAL 618
            :||:..|..:.::.::.|:|:|.:|.   |.:....|.|..   ||..:.......||.:.:..|
 Frog   284 VDAMKHEEAILTTMDIVHDGFGFMLAFGDLCWVPFTYSLQG---YFLVRHPQELSTYAAVGIILL 345

  Fly   619 LSLGLLVKRFSCAYKYKYRLNSQSPIFANIETIHTYQGSRLLLSGMWGWVRQPNYLGDIVALLAL 683
            .::|.::.|.|.:.|..:|.|...|....:|||.|..|.|||:||.||.||.||||||::
 Frog   346 NAVGYIIFRGSNSQKNAFRRNPADPKVVGLETIPTATGKRLLVSGWWGLVRHPNYLGDLI----- 405

  Fly   684 AAPMALRPAWPPVLGLSLII---------LLLLHRATRANARNQARYHSSWQRYSTQVRSYILPR 739
               |||  ||....|||.|:         :||:||..|...:...:|..:||.|..:|...|.|.
 Frog   406 ---MAL--AWSLPCGLSNILPYFYVIYFTVLLVHREARDEHQCMKKYGVAWQEYCRRVPYRIFPY 465

  Fly   740 VY 741
            :|
 Frog   466 IY 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LBR	NP_726114.1	ICMT	304..741	CDD:473892	130/453 (29%)
tm7sf2	XP_031755653.1	ICMT	59..467	CDD:473892	131/461 (28%)