Protein Alignment twz and Kctd4

DIOPT Version :10

• Sequence 1: NP_001246449.1
• Gene: twz / 37456
• FlyBaseID: FBgn0034636
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_001103120.1
• Gene: Kctd4 / 691835
• RGDID: 1594637
• Length: 259
• Species: Rattus norvegicus
• Alignment Length: 262
• Identity: 72/262 - (27%)
• Similarity: 117/262 - (44%)
• Gaps: 83/262 - (31%)

  Fly   139 IDVGGTIYTSSLETLTKYPESKLAKLFNGQIPIVLDSLKQHYFIDRDGGMFRHILNFMRNSRLLI 203
            ::|||.:|.:..:||||||::.|..:.||:|....|: ..||||||||.:|||:|||:||..||:
  Rat    37 LNVGGYLYITQRQTLTKYPDTFLEGIVNGKILCPFDA-DGHYFIDRDGLLFRHVLNFLRNGELLL 100

  Fly   204 AEDFPDLELLLEEARYYEVEPMIKQLESMRKDRVRNGNYLVAPPTPPARHIKTSPRTSASPE--- 265
            .|.|.:.:||.:||.:::::.:.::::|..|..                  :.:||.:...|
  Rat   101 PEGFRENQLLAQEAEFFQLKGLAEEVKSRWKKE------------------QLTPRETTFLEITD 147

  Fly   266 -----------CNYEVVALHISPD----LGERIMLSAERALLDELFPEASQATQSSRSGVSWNQG 315
                       ||        :||    :..||:|.::..|  :.|||        ...||.|
  Rat   148 NHDRSQGLRIFCN--------APDFISKIKSRIVLVSKSRL--DGFPE--------EFSVSSN-- 192

  Fly   316 DWGQIIRFPL-----NG-----------YCKLNSV--QVLTRLLNAGF----TIEASVGGQQFSE 358
                ||:|..     ||           .|.|.::  :.:...|..||    :::.|.|....|:
  Rat   193 ----IIQFKYFIKSENGTRLVLKEDNTFVCTLETLKFEAIMMALKCGFRLLTSLDCSKGSIVHSD 253

  Fly   359 YL 360
            .|
  Rat   254 AL 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twz	NP_001246449.1	BTB_POZ_KCTD1-like	137..230	CDD:349670	39/90 (43%)
Kctd4	NP_001103120.1	BTB_POZ_KCTD4	34..119	CDD:349673	39/82 (48%)
		KCTD4_C	138..259	CDD:437155	30/142 (21%)