Protein Alignment twz and T05E12.3

DIOPT Version :10

• Sequence 1: NP_001246449.1
• Gene: twz / 37456
• FlyBaseID: FBgn0034636
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: NP_507324.1
• Gene: T05E12.3 / 180135
• WormBaseID: WBGene00011486
• Length: 261
• Species: Caenorhabditis elegans
• Alignment Length: 222
• Identity: 49/222 - (22%)
• Similarity: 87/222 - (39%)
• Gaps: 52/222 - (23%)

  Fly   137 VHIDVGGTIYTSSLETLTKYPESKLAKLFNGQIPIVLDSLKQHYFIDRDGGMFRHILNFMRN--- 198
            :.:.||||.:|:|::||.. .||.| |.:..:..:..:...:...|||....|..||||:|:
 Worm    22 IKLYVGGTEFTTSIKTLLN-TESAL-KNYVVRYELKTERTPELITIDRSPKHFDTILNFLRDGDV 84

  Fly   199 ----SRLLIAEDFPDLELLLEEARYYEVEPMIKQLESMRKDRVRNGNYLVAPPTPPAR-----HI 254
                :.|::||       :.:||.::.:..:| ||..::...|:.    |......|:     |.
 Worm    85 PLPVNELVLAE-------VRQEAEFFRLNGLI-QLCDVKSATVKK----VTISDCEAKNVFKDHF 137

  Fly   255 KTSPRTSASPECNYEVVA-------------------LHISPDLGERIMLSAERALLDELFPEAS 300
            |  |......:...|::|                   :|.......:..:...:..||..|....
 Worm   138 K--PAIINDDQKMVEILANIDKKPVLIVSFYIPRNGLIHFPSGFTFKTFVELYQNRLDVYFKVTH 200

  Fly   301 QATQSSRSGVSWNQGDWGQ-----IIR 322
            .||...:...:|:.|.:|:     |||
 Worm   201 YATDDEQPTSNWSFGIYGKRKDCDIIR 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twz	NP_001246449.1	BTB_POZ_KCTD1-like	137..230	CDD:349670	28/99 (28%)
T05E12.3	NP_507324.1	BTB_POZ	22..112	CDD:453885	28/99 (28%)