Protein Alignment MESK2 and ndrg2

DIOPT Version :10

• Sequence 1: NP_995914.1
• Gene: MESK2 / 37451
• FlyBaseID: FBgn0043070
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001008593.1
• Gene: ndrg2 / 494050
• ZFINID: ZDB-GENE-041212-15
• Length: 368
• Species: Danio rerio
• Alignment Length: 391
• Identity: 119/391 - (30%)
• Similarity: 188/391 - (48%)
• Gaps: 61/391 - (15%)

  Fly     8 TAEEAHLLGTMPVDPMDDIELRSVQLQFPNARGSILEACEQRRVPTDKGDVHVAI--QGDTAKPA 70
            |.|:..|.|..  |.:.|.|:         |...:|:..::..|.|..|.:||.:  .|:..:||
Zfish    11 TEEKPLLPGQS--DAVKDAEI---------AARILLDQGQEHTVETPHGVLHVTVHGSGNARRPA 64

  Fly    71 IITYHDLGLNYATSFAGFFNFPVMRGLLENFCVYHVTAPGQEEGAPTLPEDYVYPTMDDLAAQLL 135
            |:|.||:|::..:.|:..|.|..|:.:::||.|.|:.||||||||...|..|.|.:||.::..|.
Zfish    65 ILTIHDVGMDSKSCFSTLFRFEEMQEIVKNFTVVHIDAPGQEEGAAVYPAGYQYASMDQVSEMLP 129

  Fly   136 FVLSHFGLKSVIGFGVGAGANILARFAHAHPDKVGALCLINCVSTQSGWIEWGYQSFNARFLRTK 200
            .||..|..:::||.||||||.||:||...:|:.|..|.|:|......||::|...       :..
Zfish   130 AVLQFFNFRTIIGVGVGAGAYILSRFTLNNPEAVEGLVLVNVDPNARGWMDWAAH-------KLS 187

  Fly   201 GMTQGVIDYLMWHHFGRNPEERNHDLVQMYKQHFERGVNPTNLAMLINAYIHRNDLHLARTPPGT 265
            .:|..:.|.::.|.|.:.....|.:|:|.:::...:..|..|:.:...:|:.|.||.|.|.
Zfish   188 NLTSSLSDQIISHLFSQQELSANTELIQTHRERITKAPNLLNIELFWKSYLGRRDLSLDRN---- 248

  Fly   266 PGSETAATTLKMPVINITGSLSPHVDDTVTFNGRLDPTNSSWMKISDCALVLE-EQPAKLAEAFR 329
                   .|.|.||:.:.|..:|:.:..|..|.:||||.:|::|::|...:.: .||:||.|||:
Zfish   249 -------NTFKCPVMLVVGDQAPYEEAAVECNSKLDPTTTSFLKMADAGGMPQLTQPSKLTEAFK 306

  Fly   330 LFLQGEGY-----ATPLSTPASSPCGTKYHTYSSIFFANFREQQQQAMEERDRERERERDRQRQL 389
            .|:||.||     .|.||...::...:.|                        ..|..|.|.|.|
Zfish   307 YFIQGMGYMASSCMTRLSRSRTTSLSSSY------------------------SMEGSRSRSRTL 347

  Fly   390 S 390
            |
Zfish   348 S 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MESK2	NP_995914.1	alpha/beta hydrolases	51..337	CDD:473884	98/288 (34%)
ndrg2	NP_001008593.1	Ndr	40..316	CDD:397285	100/293 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	330..368		7/43 (16%)