Protein Alignment MESK2 and Ndrg3

DIOPT Version :10

• Sequence 1: NP_995914.1
• Gene: MESK2 / 37451
• FlyBaseID: FBgn0043070
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_063139447.1
• Gene: Ndrg3 / 296318
• RGDID: 1359424
• Length: 436
• Species: Rattus norvegicus
• Alignment Length: 339
• Identity: 136/339 - (40%)
• Similarity: 194/339 - (57%)
• Gaps: 16/339 - (4%)

  Fly    20 VDPMDDIELRSVQ--LQFPNARGSILE-ACEQRRVPTDKGDVHVAIQG--DTAKPAIITYHDLGL 79
            :|.:.|::|..::  |...|...:..: .|::..:.|..|.|||.|:|  ...:|.|:||||:||
  Rat     1 MDELQDVQLTEIKPLLNDKNGTRNFQDFDCQEHDIETPHGMVHVTIRGLPKGNRPVILTYHDIGL 65

  Fly    80 NYATSFAGFFNFPVMRGLLENFCVYHVTAPGQEEGAPTLPEDYVYPTMDDLAAQLLFVLSHFGLK 144
            |:.:.|..||||..|:.:.::|.|.||.||||:|.||:.|..|.|||||:||..|..||:|..:|
  Rat    66 NHKSCFNTFFNFEDMQEITQHFAVCHVDAPGQQEAAPSFPTGYQYPTMDELAEMLPPVLTHLSMK 130

  Fly   145 SVIGFGVGAGANILARFAHAHPDKVGALCLINCVSTQSGWIEWGYQSFNARFLRTKGMTQGVIDY 209
            |:||.||||||.||:|||..||:.|..|.|||......|||:|...       :..|:|..|:|.
  Rat   131 SIIGIGVGAGAYILSRFALNHPELVEGLVLINIDPCAKGWIDWAAS-------KLSGLTTNVVDI 188

  Fly   210 LMWHHFGRNPEERNHDLVQMYKQHFERGVNPTNLAMLINAYIHRNDLHLARTPPGTPGSETAATT 274
            ::.||||:...:.|.||:|.|:.|..:.:|..||.:.:.:|..|.||.:.|  |....::....|
  Rat   189 ILAHHFGQEELQANLDLIQTYRLHIAQDINQENLQLFLGSYNGRRDLEIER--PILGQNDNRLKT 251

  Fly   275 LKMPVINITGSLSPHVDDTVTFNGRLDPTNSSWMKISDC-ALVLEEQPAKLAEAFRLFLQGEGYA 338
            ||...:.:.|..||.|:..|..|.||||.|::.:|::|| .|....||.||.|||:.||||.||.
  Rat   252 LKCSTLLVVGDNSPAVEAVVECNSRLDPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYI 316

  Fly   339 TPLS-TPASSPCGT 351
            ..:. :..||..||
  Rat   317 PYVQLSHLSSESGT 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MESK2	NP_995914.1	alpha/beta hydrolases	51..337	CDD:473884	124/288 (43%)
Ndrg3	XP_063139447.1	None