Protein Alignment MESK2 and MESK2

DIOPT Version :10

• Sequence 1: NP_995914.1
• Gene: MESK2 / 37451
• FlyBaseID: FBgn0043070
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_061517497.1
• Gene: MESK2 / 1275680
• VectorBaseID: AGAMI1_002853
• Length: 562
• Species: Anopheles gambiae
• Alignment Length: 518
• Identity: 312/518 - (60%)
• Similarity: 360/518 - (69%)
• Gaps: 76/518 - (14%)

  Fly     1 MPSAPTHTAEEAHLLGTMPVDPMDDIELRSVQLQFPNARGSILEACEQRRVPTDKGDVHVAIQGD 65
            |||||.||||||.|||.|||||||||||||||||:||.||||:.||:.|||||||||:.||:|||
Mosquito    86 MPSAPAHTAEEARLLGAMPVDPMDDIELRSVQLQYPNQRGSIVGACDLRRVPTDKGDILVAVQGD 150

  Fly    66 TAKPAIITYHDLGLNYATSFAGFFNFPVMRGLLENFCVYHVTAPGQEEGAPTLPEDYVYPTMDDL 130
            |.||||:||||||||||:|||||||||.||.||:|||||||.|||||:||||.||||||||.|:|
Mosquito   151 TTKPAIVTYHDLGLNYASSFAGFFNFPTMRSLLDNFCVYHVNAPGQEDGAPTFPEDYVYPTFDEL 215

  Fly   131 AAQLLFVLSHFGLKSVIGFGVGAGANILARFAHAHPDKVGALCLINCVSTQSGWIEWGYQSFNAR 195
            |:|:|||::||.|||:||||||||||||||||.|:||||||||||||.||.:||||||||..|.|
Mosquito   216 ASQMLFVMTHFNLKSIIGFGVGAGANILARFALANPDKVGALCLINCSSTAAGWIEWGYQLLNTR 280

  Fly   196 FLRTKGMTQGVIDYLMWHHFGRNPEERNHDLVQMYKQHFERGVNPTNLAMLINAYIHRNDLHLAR 260
            .||||||||||:||||||||||||||||.||||:||.:|||.:||.||||||:|||.|.||::||
Mosquito   281 NLRTKGMTQGVLDYLMWHHFGRNPEERNLDLVQLYKSNFERSINPVNLAMLIDAYIKRTDLNIAR 345

  Fly   261 TPPGTPGSETAATTLKMPVINITGSLSPHVDDTVTFNGRLDPTNSSWMKISDCALVLEEQPAKLA 325
            ||.|:|  :|:|.:|||||:||||:||||:||||||||||.|..::|||||||.|||||||.|||
Mosquito   346 TPSGSP--QTSAPSLKMPVLNITGALSPHIDDTVTFNGRLIPEKTNWMKISDCGLVLEEQPGKLA 408

  Fly   326 EAFRLFLQGEGYATPLSTPASSPCGTKYHTYSSIFFANFREQQQQAMEERDRERERERDRQRQLS 390
            |||||||||||||     |..|| ..||||.::
Mosquito   409 EAFRLFLQGEGYA-----PTFSP-HAKYHTTTA-------------------------------- 435

  Fly   391 LRVGNRLRETAINCTSSNSNTTAGQGDNNNADGRSVDGDDQDLE--NGN------GCAGGNGTGT 447
             ........||||..::|:|.......||| :..|....:|:.:  |||      |..||.|.|.
Mosquito   436 -TAATAAASTAINRHNNNNNNNNHNNVNNN-EPVSCHNHNQEFDKLNGNVLAAGGGGGGGGGGGG 498

  Fly   448 GNGNRAYVTTD--------------------------TSGTLYYGTQSNKIRITENPLPEPVS 484
            |.|:...:.|.                          .||.:|...::..||||||||||.|:
Mosquito   499 GGGSADQLQTSNGNGGGGISGITATANISSTGSACIGASGAIYERAKNGAIRITENPLPENVA 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MESK2	NP_995914.1	alpha/beta hydrolases	51..337	CDD:473884	225/285 (79%)
MESK2	XP_061517497.1	None