DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4266 and rbm15

DIOPT Version :9

Sequence 1:	NP_001097394.1	Gene:	CG4266 / 37411	FlyBaseID:	FBgn0034598	Length:	1306	Species:	Drosophila melanogaster
Sequence 2:	XP_001335820.1	Gene:	rbm15 / 798517	ZFINID:	ZDB-GENE-041008-192	Length:	853	Species:	Danio rerio

Alignment Length:	984	Identity:	180/984 - (18%)
Similarity:	269/984 - (27%)	Gaps:	423/984 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 GDSRSPTPDRDRYKRSRRNSRSRTRS---PRGR------GAGGGTGNDRRRRGTRSRSRSRSPRS 445
            |..|||..     ||||.....|.|.   |..:      .:|||:.|        ..|.|:|...
Zfish     3 GKERSPVK-----KRSRALDDIRDRGGSHPTSKKMGVISNSGGGSNN--------GNSSSKSDGG 54

  Fly   446 SRRRG----SRDRDRMD-------------------------RSNRDKERDREHERERRKKGLPD 481
            |.|||    .||....|                         .|:...|..|.:.|...:..||.
Zfish    55 SARRGLLGDKRDGREFDGHVSSRTGNNHGYTSPVASSSGKNHASSLSLEAARTNSRGEARAPLPT 119

  Fly   482 IKKEHLSVCSTTLWVGHLSKLVYQEELSD----TFGEYGDI-VSIDQIVPRGCAFIVMNRRQDAH 541
            .:.|:     .||.:..|...:..||:.|    .|.::||: |.|.::.....||:...|..||.
Zfish   120 NESEY-----KTLKISELGSQLSDEEIEDGLFHEFKKFGDVSVKISRVNDERIAFVNFRRPDDAR 179

  Fly   542 KAMQALKNHKLQGRAITISWAAGKGVKSKEWKDYWDLELGVTYIPWSKLSSDTDFDALEEGGMFD 606
            .|..|      :||.:                                              ::|
Zfish   180 AAKHA------RGRLV----------------------------------------------LYD 192

  Fly   607 EDTMPIQMKQKINQAKNAAKEHKGASIAEAAGAPSVGVPPPNLIFGIDTTQPPPVGPVGPVGPPP 671
            .   |::::......:.:....|....:..||...:            .||.|.        .|.
Zfish   193 R---PLKIEAVYLNRRRSRSPVKEDHFSVVAGHRHL------------HTQRPL--------SPT 234

  Fly   672 GPGAPPPGLMGMVRGQFPMAPPMGINMPPPIMMPPTNMPPPMMMPTTNMPPPMMMPPTMMPPGFP 736
            |.|.....|..:..|:.|         |||        |||:         |..:........:.
Zfish   235 GLGYRDYRLQQLALGRLP---------PPP--------PPPL---------PRELEREREFAFYE 273

  Fly   737 GIGGPPHPMALPPGAPFPPPGAVPPPIPSGGQISNSGNVSDDQMDIEMDLEDAPPLPPQQQANFN 801
            ....|.:  .....|||.....:.|              .||                 |:||..
Zfish   274 ARARPAY--IAERAAPFREEDFISP--------------EDD-----------------QRANRT 305

  Fly   802 PSPSNVDLSPAAMANEM---FQQRDRERDRDNRDRSRGPGNSRWGGRDDVVEAAERWRAENGG-- 861
            ....|:|::  ...|::   |::.....:.|.:..:||..::....:.:.::.|.|.:....|
Zfish   306 LFLGNLDIT--VTENDLRRAFERFGTITEVDIKRPTRGQSSTYGFLKFENLDMAHRAKISMSGKV 368

  Fly   862 ----------GGGGPGS-----GLGP----NAAFNEARARLNLNPIEH----------------- 890
                      |...|.:     ||||    .|...|......:..|::
Zfish   369 VGRNPIKIGYGKATPTTRLWVGGLGPWVPLTALAREFDRFGTIRTIDYRKGDTWAYIQYESLDAA 433

  Fly   891 --------GMP--------RPDFMDFDNRGGPGGPRGMGPRGNHNGGGPGGDFFPPNMNHNRFNQ 939
                    |.|        |.||.|.::|                             ...:|.|
Zfish   434 QAACTHMRGFPLGGPDRRLRVDFADTEHR-----------------------------YQQQFLQ 469

  Fly   940 PTSL--------------------MQMRIPPPASFNQRMGGPAGNGGNGVGPMFMRNQGGGPGGA 984
            |..|                    ::.|.|||..|.:|             .::
Zfish   470 PLPLQHYEIMAESFVHRATPEAIRVRERTPPPLHFRER-------------ELY----------- 510

  Fly   985 GPSGGGPGGAGTGGGGPGGRQ--QGPGFFNPRNPFNDNQRGRGGQSGGGVRGVGGGGGG------ 1041
                     ||.....|..|:  :.|.|    .|....:|.|..::....|.:.|....
Zfish   511 ---------AGAEWPAPTIRERVRTPAF----EPLEHLERERRREAWSLERELPGREAARKRRLM 562

  Fly  1042 --------GPGGRGRWSDDEDEGGNNFKRRGGP---GGPGGNRFRGERGGEMMDDRRGNNSRGGR 1095
                    .|.....|:         .:||..|   |.|||                  :||.||
Zfish   563 EDGRHLECSPDSSSEWA---------ARRRRPPSLEGSPGG------------------SSRDGR 600

  Fly  1096 GGPREDRERPGFGNR----RGSRDDSNR-------HSISSTDEGNKAASETEPKPKNVETELGST 1149
               ..|.|||...:|    |.||...:|       .|.|:..|.:..||..|.|.|..::..|
Zfish   601 ---FSDSERPARADRVSPARESRSSLDRVPGEKRIKSNSNLSESSIGASPAERKRKAGDSAKG-- 660

  Fly  1150 NTGAPAAATRVDTEEDWDQELQDYEARMEAQKPGERASQSANSPPQEKLPAENENFAKPAD---V 1211
                   |::.|..|...:..|     ...|..|.:.|.:.|.    .|..:|.||  ||.   :
Zfish   661 -------ASKRDRSESSSKSNQ-----ASKQDAGGKLSMAWNG----MLLLKNSNF--PASMHLL 707

  Fly  1212 TGDPLVAKS 1220
            .||..||.|
Zfish   708 EGDLSVATS 716

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4266	NP_001097394.1	CID	7..125	CDD:239621
		RRM	<488..>593	CDD:223796	20/109 (18%)
		RRM_SCAF4_SCAF8	490..566	CDD:240673	20/80 (25%)
		DUF2413	1147..>1254	CDD:287302	20/77 (26%)
		Herpes_DNAp_acc	<1206..1304	CDD:282746	7/18 (39%)
rbm15	XP_001335820.1	RRM1_RBM15	124..201	CDD:240997	22/136 (16%)
		RRM2_RBM15	297..383	CDD:240999	16/104 (15%)
		RRM3_RBM15	386..458	CDD:241001	12/71 (17%)
		Herpes_ICP4_C	495..>685	CDD:332854	54/270 (20%)
		SPOC	684..850	CDD:311609	13/39 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23189
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100