Protein Alignment: CG4266 and Scaf8

• Sequence 1: NP_001097394.1
• Gene: CG4266
• FlyBaseID: FBgn0034598
• Length: 1306
• Species: Drosophila melanogaster
• Sequence 2: NP_598884.2
• Gene: Scaf8
• MGIID: 1925212
• Length: 1268
• Species: Mus musculus
• Alignment Length: 1485
• Identity: 429/1486 (29%)
• Similarity: 592/1486 (40%)
• Gaps: 481/1486 (32%)

  Fly     1 METVVAFNNELSGLYDSRPPISKAKMAAITKSAMRAIKLYKHVVQSVEKFILKCKPEYKVPGLYV 65
            ||.|..||:||..|.|.:||||||||..|||:|::|||.||||||||||||.|||||||||||||
Mouse     1 MEAVKTFNSELYSLNDYKPPISKAKMTQITKAAIKAIKFYKHVVQSVEKFIQKCKPEYKVPGLYV 65

  Fly    66 IDSIVRQSRHQYGMDKDLFAPRFQRNLTETFANLFRCAPEDKSRIIRVLNLWQKNNVFKSEVIQP 130
            |||||||||||:|.:||:|||||..|:..||.||:||..:|||:|:|||||||||||||||:|||
Mouse    66 IDSIVRQSRHQFGQEKDVFAPRFSNNIISTFQNLYRCPGDDKSKIVRVLNLWQKNNVFKSEIIQP 130

  Fly   131 IFDLA---------------------DPNHPIYHQMPPVGGSGGQGGGVGPGPSSSGALSLADIS 174
            :.|:|                     .|..|:....|.....|.....|....::....::|.|.
Mouse   131 LLDMAAGIPPPVVTPVLASTTAAMSNTPGTPVTPVTPANVVQGLPDPWVSQIANTDTLAAVAQIL 195

  Fly   175 SGPNGLN-----------------------SSGMEISMNSSGGDDKMGGA----MPDLSLG---- 208
            ..|.|..                       .:|:.:.:.:.........|    :..|..|
Mouse   196 QSPQGQQLQQLIQTLQIQQQKPQPSILQALDAGLVVQLQALTAQLTAAAAAANTLTPLDQGVSFN 260

  Fly   209 ---HEKFGGGSSSSKRHYSEQHYSKRQSVVSCSSKTSKSHHHKREYVKSSHDIDYQVREIIEEED 270
               .::|..|..|   .:||:  ||::......|..|:|         .::.|.:|:.|.::::
Mouse   261 KKLMDRFDFGEDS---EHSEE--SKKEMPTPQLSHVSES---------VNNSIFHQIAEQLQQQ- 310

  Fly   271 EGLQMLMADDHHCMGDDSPPTSSNLLDEKKIKQLLNNPNVLRQLHTLQNFQNLKPQEENQKHRYQ 335
                                   ||  |:..:|||..          |..|.:.|| ::|:..:.
Mouse   311 -----------------------NL--EQLRQQLLEQ----------QQPQKVTPQ-DSQEGTFG 339

  Fly   336 DE--------ALQQHFQNVMKGNAGMPPGMGMGMNMNDSMDLNKDVEFISEQQTI---EVINLDG 389
            .|        :.||||         :.|    ..|::||:|:.:....|.|.|.:   |:..
Mouse   340 SEHSASPSQGSSQQHF---------LEP----EANLDDSIDIQQQDMDIDEGQDVVEEEIFE--- 388

  Fly   390 GDSRSPTPDRDRY---KRSRRNSRSRTRSPRGRGAGGGTGNDRRRRGTRSRSRSRSPRSSRRRGS 451
                   |:..:.   .|||.:||||:||||.|.:...:|:.:|:...||||.|   |..:|:.|
Mouse   389 -------PEAKKVAVRSRSRTHSRSRSRSPRKRRSRSRSGSRKRKHRKRSRSHS---REKKRKAS 443

  Fly   452 RDRDRMDRSNRDKERDREHERERRKKGLPDIKKEHLSVCSTTLWVGHLSKLVYQEELSDTFGEYG 516
                   ||...:.|.||.|:||:|||||.::.:.|||||||||||.:.|...|::|::.|.|:|
Mouse   444 -------RSYSSERRAREREKERQKKGLPPVRSKTLSVCSTTLWVGQVDKKATQQDLTNLFEEFG 501

  Fly   517 DIVSIDQIVPRGCAFIVMNRRQDAHKAMQALK--NHKLQGRAITISWAAGKGVKSKEWKDYWDLE 579
            .|.||:.|.|||||::.|..|||:.:|:|.|.  ::|:..:.|.|:||..||||: |:|.:||::
Mouse   502 QIESINMIPPRGCAYVCMVHRQDSFRALQKLSSGSYKIGSKVIKIAWALNKGVKT-EYKQFWDVD 565

  Fly   580 LGVTYIPWSKLSSDTDFDALEEGGMFDEDTMPIQ---------MKQKINQAKNAAKEHKGASIAE 635
            ||||||||.|:..| |.|...||||.|::|:..:         :|:.:..|::.|...|.:.:..
Mouse   566 LGVTYIPWEKVKVD-DLDGFAEGGMIDQETVNAEWETVKASEPVKEPVQTAQSPAPVEKESVVTT 629

  Fly   636 AAGAPSVGVPPPNLIFGIDTTQP-------PPVGPVGPVGPPPG--PGAPPPGLMGMVRGQF-PM 690
            .|..    .|||..:..|.....       ||..||....||||  |..|||    .:|..| |.
Mouse   630 QAEV----FPPPVAMLQIPVAPAVPAVSLVPPAFPVSMPVPPPGFNPIPPPP----FLRASFNPS 686

  Fly   691 APPMGINMPPPIMMPPTNMPPPM---MMPTTNMPPPMMMPP----------TMMPPGFPGIGGPP 742
            .||.|. ||||:  ||..:|||.   ::||:.:.||:.|.|          .::|.|  .:.|..
Mouse   687 QPPPGF-MPPPV--PPPVVPPPAIPPVVPTSLVQPPLSMTPEAVKDVGFGSLVLPSG--SVAGSL 746

  Fly   743 HPMALPPGAPFPPPGAVPP----------PIPSGGQISNSGNVSDDQMDIEMDLEDAPPLPPQQQ 797
            .|..||.|..|.||....|          .||||                    |:..|:
Mouse   747 APSTLPAGNVFNPPSKAEPEEKVPHLIEHQIPSG--------------------ENTRPV----- 786

  Fly   798 ANFNPSPSNVDLSPAAMANEMFQQRDRERDRDNRDRSRGPGNSRWGG-----RDDVVEAAERWRA 857
                 .||::..|.|.:|                   :.||.|...|     |.:|...:|.
Mouse   787 -----IPSDIPSSAAMLA-------------------QPPGASSTSGILCVQRPNVSSNSEI--- 824

  Fly   858 ENGGGGGGPGSGLGPNAAFNEARARLNLNPIEHGMPRPDFMDFDNRGGPGGPRGMGPRGNHNGGG 922
                      .|:.|....|.| |.:...|       |:.::      ..|...:.|....:|.|
Mouse   825 ----------LGVRPANVSNSA-AIMGAQP-------PNILN------NSGILAIQPPNVSSGSG 865

  Fly   923 PGGDFFPPNMNHN---------RFNQPTSLM-------QMRIPPPASFNQRMGGPA--------G 963
            ..| ..|||:.:|         ....|..|:       ...:||.|...|||  ||        |
Mouse   866 LLG-VLPPNLPNNSGLVGLQPPNVTSPAGLLGTQPPIGPQNLPPLAIPAQRM--PALPMLDIRPG 927

  Fly   964 NGGNGVGPMFMRNQGGGPGGAG--------------PSGGGPGGAGTGGGGPGGRQQGPG--FFN 1012
            ......||.|...|.|.|...|              |.|..|                ||  |..
Mouse   928 LIAQAPGPRFPLLQPGIPPQRGIPPPSVLDAALHPPPRGPFP----------------PGDLFSQ 976

  Fly  1013 PRNPF---------------------NDNQRGRGG--------QSGGG--------VRGVGG--- 1037
            |..||                     |||.:..|.        ::..|        ||.|.|
Mouse   977 PERPFLAPGRPSIDNVPNPDKRIPLGNDNIQQEGDRDYRFPPIETREGITRPPQVDVRDVVGRRL 1041

  Fly  1038 GGGGGPG----------GR-----------------GR-----WSDDEDEGGNNFKRR------- 1063
            ....|||          ||                 ||     :..::..|..:|..|
Mouse  1042 DPREGPGRPPLDARDHFGRPPVDMRENLVRPSLDHLGRRDHFGFPPEKPWGPRDFDEREHRVLPV 1106

  Fly  1064 -GGPGGPGGNRFRGERGGEMMDDRRGNNSRG-GRGGPR--EDRERPGFGNRRGSRDDSNRHSISS 1124
             |||.|....|.|...|....|.|.|..:|| |:...|  :||.||  ..|:..|||.: .....
Mouse  1107 FGGPKGLHEERGRFRAGNYRFDPRSGPWNRGFGQEVHRDFDDRRRP--WERQRDRDDRD-FDFCR 1168

  Fly  1125 TDEGNKAASETEPKPKNVETELGSTNTGAPAAATRVDTEEDWDQELQDYEARMEAQKP------- 1182
            ...||:...:.            ..||..|....||          .||.....:|:.
Mouse  1169 EINGNRLGRDR------------IQNTWVPPPHARV----------FDYFEGATSQRKGDNVPQV 1211

  Fly  1183 -GERASQSANSPP---------QEKLPA----ENENFAKPADVTGDPLVAKSQTE 1223
             ||...:.|..||         .|||.:    :.|.....|.|..:.:|..::||
Mouse  1212 NGENTERHAQPPPLPVQKDPELYEKLASSGDVDKEESGTVAGVESEAVVESTETE 1266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4266	NP_001097394.1	CID	7..125	CDD:239621	89/118 (75%)
		RRM	<488..>593	CDD:223796	54/107 (50%)
		RRM_SCAF4_SCAF8	490..566	CDD:240673	36/78 (46%)
		DUF2413	1147..>1254	CDD:287302	22/99 (22%)
		Herpes_DNAp_acc	<1206..1304	CDD:282746	5/19 (26%)
Scaf8	NP_598884.2	CID	4..125	CDD:239621	90/121 (74%)
		RRM	<473..>552	CDD:223796	37/79 (47%)
		RRM_SCAF8	475..553	CDD:240908	36/78 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C358638343
eggNOG	1	0.900				E1_KOG0132
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	472	1.000	Inparanoid score	I1487
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0001380
OrthoInspector	1	1.000				T615324
orthoMCL	1	0.900				OOG5_130921
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1302
TreeFam	1	0.960
	10	9.680