DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3295 and AT4G37880

DIOPT Version :9

Sequence 1:	NP_611536.1	Gene:	CG3295 / 37382	FlyBaseID:	FBgn0034573	Length:	432	Species:	Drosophila melanogaster
Sequence 2:	NP_195501.1	Gene:	AT4G37880 / 829944	AraportID:	AT4G37880	Length:	388	Species:	Arabidopsis thaliana

Alignment Length:	426	Identity:	122/426 - (28%)
Similarity:	214/426 - (50%)	Gaps:	45/426 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SVEKDLTRVVSKLEQLHENAEADIGDIATQMSELVEVLSRAEQLVTTLNSSTQVSQDDPMGDAVS 74
            |::....||.:|.:..:           ::.:|:|.:||:      .::.:..:.::.|..|.:.
plant     5 SIKDAFDRVATKQKLSY-----------SKTNEIVHMLSQ------EIDKALSILEETPSSDTML 52

  Fly    75 MQVETEPTAPQRLTERQVESVRNALARCHERVQKLSTEHRDLHGSISKIGKAIDRNFSADFSSTM 139
            :.        .|.....|:.|...:|    .:.:|....::||.:::|..|.:::..:.|.|...
plant    53 LD--------HRSILADVKKVFMEIA----PITQLEATEKELHAALTKYPKVLEKQLNPDISKAY 105

  Fly   140 RVDVLQDEENLMLLNKAIAKHYCRQGMDDVARTLIRECKMSPEHAQDVFDSEREFADIYGIWVKI 204
            |.:|   |.:..::|:.||..:.||||.|:.     :|.:: |..:....:.:.|.::|.|...:
plant   106 RHNV---EFDTHIVNQIIANFFYRQGMFDIG-----DCFVA-ETGESECSTRQSFVEMYRILEAM 161

  Fly   205 QKRDLTDALKWAKMYSQQLSDRHSLIEFRLHRMRFMQLVSYGLDSQREAISYARLNFKKFAVRYE 269
            ::|||..||.||...|.:|.:..|.:|.:||.:.|:: ::.|.:| :|||.|||.:...||....
plant   162 KRRDLEPALNWAVSNSDKLKEARSDLEMKLHSLHFLE-IARGKNS-KEAIDYARKHIATFADSCL 224

  Fly   270 HEIANLMASFIYLPSGLENSPYKHFLGQEKWTELSFIFLKDACQLLGISKNSALSVVVNAGCTAL 334
            .||..||.|.:: ...|:.|||..||....|........:..|.|||.|..|.||:.|.||..||
plant   225 PEIQKLMCSLLW-NRKLDKSPYSEFLSPALWNNAVKELTRQYCNLLGESSESPLSITVTAGTQAL 288

  Fly   335 PALLNIKQVMQSRQVLGMWNGCDELPIEIDLQPEFRFHSIFACPILRQQTSEDNPPKKLTCGHVI 399
            |.||....|:.:.:.|. |...::||::..|..||:|||:|.||:.::|:|:||||..::||||:
plant   289 PVLLKYMNVVMANKKLD-WQTMEQLPVDAQLSEEFQFHSVFVCPVSKEQSSDDNPPMMMSCGHVL 352

  Fly   400 SNDALHKLSVG---HILKCPYCPVEQNAEEAVRIYF 432
            ....::|:|..   ...||||||.:.:.....:::|
plant   353 CKQTINKMSKNGSKSSFKCPYCPTDVDISRCRQLHF 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3295	NP_611536.1	COG5109	88..432	CDD:227440	110/346 (32%)
		LisH	152..181	CDD:128913	9/28 (32%)
		CTLH	193..250	CDD:128914	18/56 (32%)
		CRA	252..343	CDD:214806	36/90 (40%)
		zf-RING_UBOX	377..416	CDD:290181	15/41 (37%)
AT4G37880	NP_195501.1	COG5109	28..388	CDD:227440	116/390 (30%)
AT4G37880	NP_195501.1	CLTH	150..292	CDD:402305	53/144 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	1.000	Domainoid score	I2915
eggNOG	1	0.900	-	-		E1_COG5109
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5668
Inparanoid	1	1.050	191	1.000	Inparanoid score	I1376
OMA	1	1.010	-	-		QHG55101
OrthoDB	1	1.010	-	-		D987270at2759
OrthoFinder	1	1.000	-	-		FOG0002102
OrthoInspector	1	1.000	-	-		otm3073
orthoMCL	1	0.900	-	-		OOG6_102297
Panther	1	1.100	-	-	O	PTHR12170
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1554
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840