DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9993 and 4CL1

DIOPT Version :9

Sequence 1:	NP_611518.1	Gene:	CG9993 / 37358	FlyBaseID:	FBgn0034553	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_175579.1	Gene:	4CL1 / 841593	AraportID:	AT1G51680	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	143/535 - (26%)
Similarity:	252/535 - (47%)	Gaps:	63/535 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 YSDKVMQVYDPTGEELTGSQLLEQSRRLAHAFQRLKLQRGDVVGISAKNTTYLTEVVIAALLNGT 103
            ::.|...:..|||...|.|.:...||::|..|.:|.:.:.|||.:...|........:||...|.
plant    51 FATKPCLINGPTGHVYTYSDVHVISRQIAANFHKLGVNQNDVVMLLLPNCPEFVLSFLAASFRGA 115

  Fly   104 PINPLHPDFDAETTAYMFEITKPKVIFCDLDNYQTLSAVKSSLKFKTEIILLTGTLPGVRNIQDL 168
            .....:|.|.....|...:.:..|:|..:......:..:::........|....::|
plant   116 TATAANPFFTPAEIAKQAKASNTKLIITEARYVDKIKPLQNDDGVVIVCIDDNESVP-------- 172

  Fly   169 LADGCTGYDEKT--------LFACPHLCGDDTAFIITSSGVTGLPKGVTRSHRSLLNS------A 219
            :.:||..:.|.|        :.....:..||...:..|||.|||||||..:|:.|:.|      .
plant   173 IPEGCLRFTELTQSTTEASEVIDSVEISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDG 237

  Fly   220 KIPQL-FTSDTVLFCFSPLYWISCIFTLLASLVNGCR---RIITNRPFSVAYFADLVERHQVSFV 280
            :.|.| |.||.|:.|..|::.   |:.|.:.::.|.|   .|:....|.:....:|::|.:|:..
plant   238 ENPNLYFHSDDVILCVLPMFH---IYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVA 299

  Fly   281 LTVPHHMALLAKSPERQEL-AAKMQCVQSFVCSGSKVPMGIWRQLYELLGAN----RFAVLYGLT 340
            ..||..:..:|||.|.::. .:.::.|:|     ...|:|  ::|.:.:.|.    :....||:|
plant   300 PMVPPIVLAIAKSSETEKYDLSSIRVVKS-----GAAPLG--KELEDAVNAKFPNAKLGQGYGMT 357

  Fly   341 ETG-------GISKNVGGPL----GSEGRLLRNVQVRVVDPH-GQSLGPNQTGQILVRLNLRWGG 393
            |.|       |.:|.   |.    |:.|.::||.::::|||. |.||..||.|:|.:|.:....|
plant   358 EAGPVLAMSLGFAKE---PFPVKSGACGTVVRNAEMKIVDPDTGDSLSRNQPGEICIRGHQIMKG 419

  Fly   394 YYHNPQETQVTVTPDGKWLLTGDHGYFDDEGCLHFQSRDTDVFKYNHFPIYPKQIEDVILHLPGV 458
            |.:||..|..|:..|| ||.|||.|..||:..|....|..::.||..|.:.|.::|.:::..|.:
plant   420 YLNNPAATAETIDKDG-WLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDI 483

  Fly   459 HEVAVFGIPDEVSTNLTACAVVRNEDELGAQLTEADVKGVVAQHLSDAFHIR-GGVFFVDNLPKT 522
            .:|||..:.:|.:..:....||:::|   ::|:|.|||..|::.:  .|:.| ..|||.:::||.
plant   484 TDVAVVAMKEEAAGEVPVAFVVKSKD---SELSEDDVKQFVSKQV--VFYKRINKVFFTESIPKA 543

  Fly   523 QNSKVQRRKIWSQLS 537
            .:.|:.|:.:.::|:
plant   544 PSGKILRKDLRAKLA 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	142/528 (27%)
CG9993	NP_611518.1	AFD_class_I	45..528	CDD:302604	140/518 (27%)
4CL1	NP_175579.1	PLN02246	16..560	CDD:215137	143/535 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920