DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9993 and CG11407

DIOPT Version :9

Sequence 1:	NP_611518.1	Gene:	CG9993 / 37358	FlyBaseID:	FBgn0034553	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_650831.1	Gene:	CG11407 / 42354	FlyBaseID:	FBgn0038733	Length:	538	Species:	Drosophila melanogaster

Alignment Length:	542	Identity:	162/542 - (29%)
Similarity:	275/542 - (50%)	Gaps:	45/542 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 YDSFEKIWSGPKDKEYYGPDMTLGEVALIILRLYSDKVMQVYDPTGEELTGSQLLEQSRRLAHAF 70
            ||:..|||||.:.:.|:.|.:::||:....:|.:...:.|:.......||.::|...:..:|...
  Fly     9 YDADRKIWSGDQLEYYFDPHLSIGEIIFNEMRRHPQLIAQISATENTILTRAELQANAMHIASYM 73

  Fly    71 QRLKLQRGDVVGISAKNTTYLTEVVIAALLNGTPINPLHPDFDAETTAYMFEITKPKVIFCDLDN 135
            :.|.|.:.|:|||.|:|||:::.|..|...||...:.|:..::..|...:|.||:|.:||||.|.
  Fly    74 RSLGLLQMDIVGIIARNTTHISAVAYACFFNGIAFHSLNISYEQSTIEKLFSITRPNIIFCDGDE 138

  Fly   136 YQTLSAVKSSLKFKTEIILL----TGTL--------PGVRNIQDL-LADGCTGYDEKTLFACPHL 187
            ::.:.:..:.|..|  ||.:    :|::        |..:|.|.: |..|
  Fly   139 FEKVRSATAQLDVK--IITMRNHPSGSIRIDQVLSTPIEKNFQPVRLEQG--------------- 186

  Fly   188 CGDDTAFIITSSGVTGLPKGVT-RSHRSLLNSAKIPQLFTSDTVLFCFSPLYWISCIFTLLASLV 251
             .|.|..|:.|||.||:||.|| .:.|.:|||:   ...|::.|.:..|.|.||:.:.|.:.|.|
  Fly   187 -NDQTLAILCSSGTTGIPKAVTITNSRQILNSS---HSLTTNDVQYSHSTLDWITGLLTTVTSGV 247

  Fly   252 NGCRRIITNRPFSVAYFADLVERHQVSFVLTVPHHMALLAKSPERQELAAKMQCVQSFVCSGSKV 316
            ...:|||.:..|...:|..|||.||:::::..|.|||::..||  ....:.:..::.::..||:.
  Fly   248 FSTKRIIADNIFDPEFFMRLVEEHQITWIIQAPAHMAMMVNSP--SFTTSDLSSLRYYLFGGSRA 310

  Fly   317 PMGIWRQLYELLGANRFAVLYGLTETG---GISKNVGGPLGSEGRLLRNVQVRVVDPHGQSLGPN 378
            .:....::...|..:.....||.||.|   .::.:......|.|||:..::::|:...|:||||:
  Fly   311 SVETQHRIRSRLSKDCLHFAYGFTELGSMAALNLHFDEKPNSVGRLVAGLKLKVICEKGESLGPD 375

  Fly   379 QTGQILVRLNLRWGGYYHNPQETQVTVTPDGKWLLTGDHGYFDDEGCLHFQSRDTDVFKYNHFPI 443
            :.|::.:.....|.|||.||:||. .:.....|..|||.||.||:|.::...|..|:.|:.:...
  Fly   376 EVGELCLWNGQYWAGYYGNPEETH-KMRDHHNWFHTGDLGYVDDDGFIYIVERKKDMLKFQNIMY 439

  Fly   444 YPKQIEDVILHLPGVHEVAVFGIPDEVSTNLTACAVVRNEDELGAQLTEADVKGVVAQHLSDAF- 507
            ||.:||.||..:|.|.||.|||:.:|::.:....|||:..   |:.||..|:...|..|:...:
  Fly   440 YPNEIESVISKMPDVVEVCVFGVWNEINGDEATAAVVKKR---GSALTAQDIVDYVETHIDAKYK 501

  Fly   508 HIRGGVFFVDNLPKTQNSKVQR 529
            .:.||...|::|.::.|.|..|
  Fly   502 QLNGGAIIVEDLVRSPNGKTNR 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9993	NP_611518.1	CaiC	21..532	CDD:223395	155/527 (29%)
CG9993	NP_611518.1	AFD_class_I	45..528	CDD:302604	149/500 (30%)
CG11407	NP_650831.1	CaiC	26..523	CDD:223395	153/523 (29%)
CG11407	NP_650831.1	Firefly_Luc_like	47..522	CDD:213279	149/501 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471332
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26958
OrthoDB	1	1.010	-	-		D24284at7147
OrthoFinder	1	1.000	-	-		FOG0004528
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X778
	8	7.860