DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17999 and 4CL1

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_175579.1	Gene:	4CL1 / 841593	AraportID:	AT1G51680	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	541	Identity:	149/541 - (27%)
Similarity:	250/541 - (46%)	Gaps:	50/541 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 DFYGP-EMTLGEVIMRVLQINADQVMQICDTTGQELTGAQLAQQSARIAQAFKRLGLRRGDVVGI 84
            |.|.| .::|.:.|.:.:...|.:...|...||...|.:.:...|.:||..|.:||:.:.|||.:
plant    31 DIYIPNHLSLHDYIFQNISEFATKPCLINGPTGHVYTYSDVHVISRQIAANFHKLGVNQNDVVML 95

  Fly    85 SANNSTYLTSVIIAALLRGIPINPLHPEFTEETVKYMYDITEPKVIFCDVENYHIIKTVNGKLQN 149
            ...|........:||..||......:|.||...:......:..|:|..:......||    .|||
plant    96 LLPNCPEFVLSFLAASFRGATATAANPFFTPAEIAKQAKASNTKLIITEARYVDKIK----PLQN 156

  Fly   150 PAKIYLV----NGKL---EGVLDISEMLNDEDSITAAAYVPCPKLHGDHTAFIVCSSGTTGMPKG 207
            ...:.:|    |..:   ||.|..:|:  .:.:..|:..:...::..|....:..||||||:|||
plant   157 DDGVVIVCIDDNESVPIPEGCLRFTEL--TQSTTEASEVIDSVEISPDDVVALPYSSGTTGLPKG 219

  Fly   208 VTRSHRSLLCNC------KNPNTYTR-DSVLLSFSPLYWISG-TIILLASLLNGCRRIITNRPYS 264
            |..:|:.|:.:.      :|||.|.. |.|:|...|::.|.. ..|:|..|..|...:|..: :.
plant   220 VMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPK-FE 283

  Fly   265 VEYLLQLVARHKVTFLFLASHQIALLSKHDSDVMELKAQLQSIRVLIGAGSKVCKAVCRRMYELI 329
            :..||:|:.|.|||...:....:..::|  |...| |..|.||||:....:.:.|.:...:....
plant   284 INLLLELIQRCKVTVAPMVPPIVLAIAK--SSETE-KYDLSSIRVVKSGAAPLGKELEDAVNAKF 345

  Fly   330 GNQRFVVGYGLSEMGG-LSKNVG-----GPV--GCEGKVMRNVELRVLDKLKMP-----LGINEV 381
            .|.:...|||::|.|. |:.::|     .||  |..|.|:||.|::::|    |     |..|:.
plant   346 PNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVD----PDTGDSLSRNQP 406

  Fly   382 GIIYARLRFKWAGYYRNPEATRRALSSDGMWFRTGDIGYLDSEGYLYIQTRDTDVFKFNNFQIYP 446
            |.|..|......||..||.||...:..|| |..|||||.:|.:..|:|..|..::.|:..||:.|
plant   407 GEICIRGHQIMKGYLNNPAATAETIDKDG-WLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAP 470

  Fly   447 EQIEEFILRLPGVSEACVFGIPDAVSTNLTACAVVRTKSPEGERLTADHIRNIVEHHLSGAYHIR 511
            .::|..::..|.:::..|..:.:..:..:....||::|..|   |:.|.::..|...:  .::.|
plant   471 AELEALLIGHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSE---LSEDDVKQFVSKQV--VFYKR 530

  Fly   512 -GGVYFIDSLPKTPNDKLQRR 531
             ..|:|.:|:||.|:.|:.|:
plant   531 INKVFFTESIPKAPSGKILRK 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	147/537 (27%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	143/519 (28%)
4CL1	NP_175579.1	PLN02246	16..560	CDD:215137	149/541 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920