DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17999 and OPCL1

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_564115.1	Gene:	OPCL1 / 838639	AraportID:	AT1G20510	Length:	546	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	139/548 - (25%)
Similarity:	247/548 - (45%)	Gaps:	40/548 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 SRTWFGPRGKDFYG--------PEMTLGEVIMRVLQINADQVMQICDTTGQELTGAQLAQQSARI 67
            ||:.|......||.        |..:|........|.:..::..|..:|||.||..:|.:....:
plant     6 SRSGFCNSNSTFYSKRTPIPLPPNPSLDVTTFISSQAHRGRIAFIDASTGQNLTFTELWRAVESV 70

  Fly    68 AQAFKRLGLRRGDVVGISANNSTYLTSVIIAALLRGIPI---NPLHPEFTEETVKYMYDITEPKV 129
            |.....:|:|:|.||.:.:.||.....|.::.:..|..|   |||:.  :.|..|.:.| :.|.:
plant    71 ADCLSEIGIRKGHVVLLLSPNSILFPVVCLSVMSLGAIITTTNPLNT--SNEIAKQIKD-SNPVL 132

  Fly   130 IFCDVENYHIIKTVNGKLQNPAKIYLVNGKLEGVLDIS---EMLNDEDSITAAAYVPCPKLHGDH 191
            .|...:   ::..::...:....:.:...:::.|.|:.   ||:..|.|.....    .::..|.
plant   133 AFTTSQ---LLPKISAAAKKLPIVLMDEERVDSVGDVRRLVEMMKKEPSGNRVK----ERVDQDD 190

  Fly   192 TAFIVCSSGTTGMPKGVTRSHRSLLCNCKN-PNTYTRDSVLLSF---SPLYWISGTIILLASLLN 252
            ||.::.|||||||.|||..|||:|:...:. .|.:..|.....|   .|::.|.|.......||.
plant   191 TATLLYSSGTTGMSKGVISSHRNLIAMVQTIVNRFGSDDGEQRFICTVPMFHIYGLAAFATGLLA 255

  Fly   253 GCRRIITNRPYSVEYLLQLVARHKVTFLFLASHQIALLSKHDSDVMELKAQLQSIRVLIGAGSKV 317
            ....||....:.:..::..:.:::.|.|.|.. .|.:...:.:|.::.|..|.|:..::..|:.:
plant   256 YGSTIIVLSKFEMHEMMSAIGKYQATSLPLVP-PILVAMVNGADQIKAKYDLSSMHTVLCGGAPL 319

  Fly   318 CKAVCRRMYELIGNQRFVVGYGLSEMGGLSKNV-----GGPVGCEGKVMRNVELRVLDKLK-MPL 376
            .|.|.....|.....:.:.||||:|..|:..:.     ....|..||:..::|.|::|.:. ..|
plant   320 SKEVTEGFAEKYPTVKILQGYGLTESTGIGASTDTVEESRRYGTAGKLSASMEGRIVDPVTGQIL 384

  Fly   377 GINEVGIIYARLRFKWAGYYRNPEATRRALSSDGMWFRTGDIGYLDSEGYLYIQTRDTDVFKFNN 441
            |..:.|.::.:......||:.|.|||...|.|:| |.||||:.|:|.:|::::..|..::.|:..
plant   385 GPKQTGELWLKGPSIMKGYFSNEEATSSTLDSEG-WLRTGDLCYIDEDGFIFVVDRLKELIKYKG 448

  Fly   442 FQIYPEQIEEFILRLPGVSEACVFGIPDAVSTNLTACAVVRTKSPEGERLTADHIRNIVEHHLSG 506
            :|:.|.::|..:|..|.:::|.|...||..........|||   ..|..|:...|...|...::.
plant   449 YQVAPAELEALLLTHPEITDAAVIPFPDKEVGQFPMAYVVR---KTGSSLSEKTIMEFVAKQVAP 510

  Fly   507 AYHIRGGVYFIDSLPKTPNDKLQRRKVL 534
            ...|| .|.|:.|:||.|:.|:.|:.::
plant   511 YKRIR-KVAFVSSIPKNPSGKILRKDLI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	134/526 (25%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	131/506 (26%)
OPCL1	NP_564115.1	4CL	26..536	CDD:341230	134/525 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920