DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17999 and 4CL2

DIOPT Version :9

Sequence 1:	NP_611517.1	Gene:	CG17999 / 37357	FlyBaseID:	FBgn0034552	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_188761.1	Gene:	4CL2 / 821678	AraportID:	AT3G21240	Length:	556	Species:	Arabidopsis thaliana

Alignment Length:	547	Identity:	151/547 - (27%)
Similarity:	250/547 - (45%)	Gaps:	55/547 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 FGPRGKDFYGP-EMTLGEVIMRVLQINADQVMQICDTTGQELTGAQLAQQSARIAQAFKRLGLRR 78
            |..|..|.|.| .:.|.:.|...:...|.:...|...||:..|.|.:...|.::|.....||:::
plant    23 FRSRLPDIYIPNHLPLHDYIFENISEFAAKPCLINGPTGEVYTYADVHVTSRKLAAGLHNLGVKQ 87

  Fly    79 GDVVGISANNSTYLTSVIIAALLRGIPINPLHPEFTEETVKYMYDITEPKVIFCDVENYHIIKTV 143
            .|||.|...||..:....:||...|......:|.||...:......:..|:|.  .::.::.|..
plant    88 HDVVMILLPNSPEVVLTFLAASFIGAITTSANPFFTPAEISKQAKASAAKLIV--TQSRYVDKIK 150

  Fly   144 NGKLQNPAKIYLVNGK---LEGVLDISEMLNDE----DSITAAAYVPCPKLHGDHTAFIVCSSGT 201
            |  |||...:.:....   .|..|..||:...|    |||.       .|:..:....:..||||
plant   151 N--LQNDGVLIVTTDSDAIPENCLRFSELTQSEEPRVDSIP-------EKISPEDVVALPFSSGT 206

  Fly   202 TGMPKGVTRSHRSLLCNC------KNPNTY-TRDSVLLSFSPLYWISG-TIILLASLLNGCRRII 258
            ||:||||..:|:.|:.:.      :|||.| .||.|:|...|::.|.. ..|:|.||..|...:|
plant   207 TGLPKGVMLTHKGLVTSVAQQVDGENPNLYFNRDDVILCVLPMFHIYALNSIMLCSLRVGATILI 271

  Fly   259 TNRPYSVEYLLQLVARHKVTFLFLASHQIALLSKHDSDVMELKAQLQSIRVLIGAGSKVCKAVCR 323
            ..: :.:..||:.:.|.|||...:....:..::|  |...| |..|.|:|::....:.:.|.:..
plant   272 MPK-FEITLLLEQIQRCKVTVAMVVPPIVLAIAK--SPETE-KYDLSSVRMVKSGAAPLGKELED 332

  Fly   324 RMYELIGNQRFVVGYGLSEMGG-LSKNVG-----GPV--GCEGKVMRNVELRVLDKLKMP----- 375
            .:.....|.:...|||::|.|. |:.::|     .||  |..|.|:||.|:::||    |
plant   333 AISAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKILD----PDTGDS 393

  Fly   376 LGINEVGIIYARLRFKWAGYYRNPEATRRALSSDGMWFRTGDIGYLDSEGYLYIQTRDTDVFKFN 440
            |..|:.|.|..|......||..:|.||...:..|| |..|||:|::|.:..|:|..|..::.|:.
plant   394 LPRNKPGEICIRGNQIMKGYLNDPLATASTIDKDG-WLHTGDVGFIDDDDELFIVDRLKELIKYK 457

  Fly   441 NFQIYPEQIEEFILRLPGVSEACVFGIPDAVSTNLTACAVVRTKSPEGERLTADHIRNIVEHHLS 505
            .||:.|.::|..::..|.:::..|..:.:..:..:....|||:|.   ..::.|.|:..|...:
plant   458 GFQVAPAELESLLIGHPEINDVAVVAMKEEDAGEVPVAFVVRSKD---SNISEDEIKQFVSKQV- 518

  Fly   506 GAYHIR-GGVYFIDSLPKTPNDKLQRR 531
             .::.| ..|:|.||:||.|:.|:.|:
plant   519 -VFYKRINKVFFTDSIPKAPSGKILRK 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	147/537 (27%)
CG17999	NP_611517.1	AFD_class_I	38..529	CDD:302604	143/519 (28%)
4CL2	NP_188761.1	PLN02246	14..553	CDD:215137	151/547 (28%)
4CL2	NP_188761.1	4CL	32..546	CDD:213272	147/538 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920