Protein Alignment CG17999 and ACSF3

DIOPT Version :9

• Sequence 1: NP_611517.1
• Gene: CG17999 / 37357
• FlyBaseID: FBgn0034552
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: XP_005256350.1
• Gene: ACSF3 / 197322
• HGNCID: 27288
• Length: 610
• Species: Homo sapiens
• Alignment Length: 571
• Identity: 130/571 - (22%)
• Similarity: 238/571 - (41%)
• Gaps: 100/571 - (17%)

  Fly    47 ICDTTGQELTGAQLAQQSARIAQAFKRL------GLRRGDVVGISANNSTYLTSVIIAALLRGIP 105
            :.|..|:. |..:|..:|.|::|...||      .||...|..:.||:::|:.:...:.:..|:.
Human    59 LVDQHGRH-TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVA 122

  Fly   106 INPLHPEFTEETVKYMYDITEPKVIFCDVENYHIIKTVNGKLQNPAKIYLVNGKLEGVLDISEML 170
            : ||:.:.....::|:...::..|:....|...::..|..||..|            :|.::..:
Human   123 V-PLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVP------------LLPLTPAI 174

  Fly   171 NDEDSITAAAYVPCPKLHG--DHTAFIVCSSGTTGMPKGVTRSH---RSLLCNCKNPNTYTRDSV 230
            . ..::...|.||.|: .|  :..|.|:.:|||||.||||..:|   |:::....:...:|:|.|
Human   175 Y-TGAVEEPAEVPVPE-QGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDV 237

  Fly   231 LLSFSPLYWISGTI-ILLASLLNG--CRRIITNRPYSV--EYLLQLVARHKVTFLFLASHQIALL 290
            :|...||:.:.|.: .||..|..|  |..:....|..|  ::|.....|..| |:.:.:....|:
Human   238 ILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINV-FMAVPTIYTKLM 301

  Fly   291 SKHDSDVMELKAQ-------LQSIRVLIGAGSKVCKAVCRRMYELIGNQRFVVGYGLSEMGGLSK 348
            ..:|....:..||       .:.||:::...:.:...|..:...:.|: ..:..||::|:|   .
Human   302 EYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGH-TLLERYGMTEIG---M 362

  Fly   349 NVGGPV-------GCEGKVMRNVELRVLDK-------------------LKMPLGINE-VGIIYA 386
            .:.||:       |..|..:..|::|::.:                   .|:..|..| .|.:..
Human   363 ALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLV 427

  Fly   387 RLRFKWAGYYRNPEATRRALSSDGMWFRTGDIGYLDSEGYLYIQTR-DTDVFKFNNFQIYPEQIE 450
            |....:..|:..||.|:.|.:.|| ||:|||. .:..:|..:|:.| ..|:.|...:::...::|
Human   428 RGPSVFREYWNKPEETKSAFTLDG-WFKTGDT-VVFKDGQYWIRGRTSVDIIKTGGYKVSALEVE 490

  Fly   451 EFILRLPGVSEACVFGIPDAV-STNLTACAVVR--------------------TKSPEGERLTAD 494
            ..:|..|.:::..|.|:||.. ...:||...:|                    ||..|...|...
Human   491 WHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARLKEHPTKRRENSILNIG 555

  Fly   495 HIRNIVE--HHLSGAYHIRGGVYF--IDSLPKTPNDKLQRRKVLGLVQQLE 541
            ..||:..  ..|:|....|.....  :.|..:|.| .|:|.|:..|.|.|:
Human   556 RKRNLASGMRALTGRMAARRAAVSSEVSSSDETDN-SLKRHKLPRLTQTLK 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	130/571 (23%)
		AFD_class_I	38..529	CDD:302604	124/557 (22%)
ACSF3	XP_005256350.1	MCS	55..546	CDD:341264	113/509 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810