Protein Alignment: Fem-1 and fem1b

• Sequence 1: NP_611508.1
• Gene: Fem-1
• FlyBaseID: FBgn0034542
• Length: 702
• Species: Drosophila melanogaster
• Sequence 2: NP_001238770.1
• Gene: fem1b
• XenbaseID: XB-GENE-999856
• Length: 629
• Species: Xenopus tropicalis
• Alignment Length: 644
• Identity: 258/645 (40%)
• Similarity: 382/645 (59%)
• Gaps: 33/645 (5%)

  Fly    61 LHLAARSGQMLSFVEILNSVSCRAVQTHLVNTNFDQPDGQSLTPLTMAAMMGNVKFVKTLLSHYD 125
            ::.||..|::|:...:|.:.:...::|.|  :...|..||..|||.:||..|:.|.|:.||.||.
 Frog    10 VYKAAAEGRVLTLAALLLNRTEPEIRTLL--STVTQHGGQRSTPLIIAARNGHSKVVRLLLEHYK 72

  Fly   126 VDLDRECNVIYDGMVVYGATALWVAAGMGHLQIVKMLVQAGAAINHNTKAQSSPLRAACYEGRLD 190
            ||:.:...|.:||.::.||||||.|||.||.::||:||..||.:||.|...|:||||||::||||
 Frog    73 VDVQQTGTVRFDGYIIDGATALWCAAGAGHYEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLD 137

  Fly   191 IVEFLIDNGADVNATNLFNNNTLMIAAYKGHHLVVKTLLQNGSRANDQALCGATALHYAAESGHL 255
            ||.||::|.|:::..|.::|..|||||||||..||:.||:..:..|.:|.|||||||:|||:|||
 Frog   138 IVRFLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQHADPNARAHCGATALHFAAEAGHL 202

  Fly   256 DVVVALLDHGATLKKNELGITPALQAAERLHEDVLEAFIERPELMSLEEQITALELLGATYANDK 320
            |:|..|:...|.:..|..|:||...|||....:|:|..:...: ...:.:|.|||||||::|||:
 Frog   203 DIVRELVKWKAAMVVNGHGMTPLKVAAESCKAEVVELLLAHSD-CDTKSRIEALELLGASFANDR 266

  Fly   321 IKYDVNKAYGYLLRAMQLRYSNPRGVIRKRVQPTVPAYDNWLETENLPELYAIKLNHHSIHMESL 385
            ..|::.|.|.||..||..|:.:|..::.|.|.|.:.||....|.....||.||..|..::|||.|
 Frog   267 ENYNLTKTYQYLYLAMLERFRDPSNILHKEVLPPIEAYGMRTECRTPQELGAIIHNTDALHMEGL 331

  Fly   386 AIRERILGRNNPELPQAIIYRGAVMADQGRFYQCQVLWNYAIDLRMRNNVSVDRDLLRFAQLFAQ 450
            .:||||||.:|.::...|||||||.||..:|.||..||.:|:.||.:.|.:..:|||||||:|:|
 Frog   332 IVRERILGSDNIDVSHPIIYRGAVYADNMQFEQCIKLWLHALQLRQKGNRNTHKDLLRFAQVFSQ 396

  Fly   451 ILRVEN--HNLTLDHVLPVLAKCQ-QEIENNKFKIKE-AKPNACPSLWQDQNNQ-NCITALYLIK 510
            ::.:..  .:..::|||    :|. .|||....:::. .:|:|..:|   :|:: |..|.|||:.
 Frog   397 MIHLNEPVKSWDVEHVL----ECSVLEIERGISRVQNPQEPDAHSAL---ENHECNLYTFLYLVC 454

  Fly   511 IVTHLARRKKDQNIDEEHIQQLFLVVRKFIQNDTRLQDGQTLLHIAVNGVMPVDEFYTNEMCRFP 575
            |.|.....:::|....:.|.:|       :..|.|.::|.||||:||:...|||:|:||::|.||
 Frog   455 ISTKTRCSEEEQPRINKQIYRL-------VHLDPRTREGCTLLHLAVDSGTPVDDFHTNDVCSFP 512

  Fly   576 CYATALVLVHCGASVVAVDSDRNTPLHILVTKVNTTQDRQAEMARILELFVEAGAHLDAVNAAGQ 640
            ....|.:|:.|||:|.|||...|:|||::|.......|.....|.|:.| ||||||.|..|...:
 Frog   513 SAPVAKLLIDCGANVNAVDQMGNSPLHVIVQYNRPISDFLTLHAIIISL-VEAGAHTDMTNKEKK 576

  Fly   641 T----AATACKLPILANRLHAHQNAHTSLKCLAARSIATNRLNFKGLIPTQLEAFIQMH 695
            |    :.|.....:|..::      ..||||||||::..:.:.::..||..||.|::.|
 Frog   577 TPLDRSTTGVSEILLKTQM------KLSLKCLAARAVRLHNIKYQNQIPRTLEEFVEFH 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fem-1	NP_611508.1	ANK	61..196	CDD:238125	62/135 (46%)
		ANK repeat	103..129	CDD:293786	14/26 (54%)
		Ank_2	105..206	CDD:289560	52/101 (51%)
		ANK	142..262	CDD:238125	70/120 (58%)
		ANK repeat	142..173	CDD:293786	19/31 (61%)
		ANK repeat	178..206	CDD:293786	16/28 (57%)
		Ank_2	180..266	CDD:289560	48/86 (56%)
		ANK repeat	208..239	CDD:293786	15/31 (48%)
		ANK repeat	241..266	CDD:293786	16/25 (64%)
		Ank_4	244..294	CDD:290365	23/50 (46%)
		ANK	548..685	CDD:238125	54/141 (38%)
		ANK repeat	548..594	CDD:293786	24/46 (52%)
		ANK repeat	596..636	CDD:293786	16/40 (40%)
fem1b	NP_001238770.1	Ank_2	13..119	CDD:289560	46/108 (43%)
		ANK repeat	50..87	CDD:293786	17/37 (46%)
		ANK	89..209	CDD:238125	70/120 (58%)
		ANK repeat	89..120	CDD:293786	19/31 (61%)
		Ank_2	94..185	CDD:289560	49/91 (54%)
		ANK repeat	122..153	CDD:293786	17/31 (55%)
		ANK repeat	155..185	CDD:293786	15/30 (50%)
		Ank_5	175..228	CDD:290568	25/53 (47%)
		ANK repeat	188..213	CDD:293786	16/25 (64%)
		ANK	<473..580	CDD:238125	47/115 (41%)
		ANK repeat	485..531	CDD:293786	24/46 (52%)
		ANK repeat	533..572	CDD:293786	16/40 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E2759_KOG0508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000				H7714
Inparanoid	1	1.050	423	1.000	Inparanoid score	I1641
OMA	1	1.010
OrthoDB	1	1.010				D133963at33208
OrthoFinder	1	1.000				FOG0003737
OrthoInspector	1	1.000				T1058380
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R4569
TreeFam	1	0.960
	10	9.870