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Protein Alignment tapas and Tdrd6

DIOPT Version :10

Sequence 1:	NP_611475.3	Gene:	tapas / 37304	FlyBaseID:	FBgn0027529	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	NP_001419573.1	Gene:	Tdrd6 / 316254	RGDID:	1305956	Length:	2129	Species:	Rattus norvegicus

Alignment Length:	1276	Identity:	249/1276 - (19%)
Similarity:	402/1276 - (31%)	Gaps:	433/1276 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 RKKELKKE------DDLDRGQITKEVAREKQKEKETRDRAVTE---TIFVTIENKKAPVMNGHGP 248
            :|..|.||      |..|| |...|:..|.:..:|...:.:.:   ..|...|.|:...::.|.|
  Rat   627 KKTVLHKELVVHILDKQDR-QYVIEILDESRTGEENISKVIAQAGYAKFQEFETKENIRLSAHSP 690

  Fly   249 RHV---------------KVANGQDKHNDGK----PPLRAI--LGN-SASQRQQDTSTVYHSPES 291
            .||               ||...|...||.|    |...|.  |.| |..|..||...|...|..
  Rat   691 GHVSGHFIAESSKIPSVKKVEGDQKAKNDNKTLSDPEALATVSLSNISTGQTAQDKEKVTSDPTL 755

  Fly   292 SFKR--PRHPRVMYPGHQR---TTGVSVNH---------RLKVTPQ-------------SDAPTP 329
            ....  ...|.....|...   |..|.|:|         :|....|             ...|:|
  Rat   756 LMLNLLKTKPDCCGKGELEVGSTVEVKVSHIENPGSFWCQLMRNAQGFRTLMCDIEDYCKSEPSP 820

  Fly   330 AVAPITPPASPEYAQTTTA--AKAT-----YKEDIHGGQG-ETGNVV---TNPKVKVPLKFDPSL 383
                        |...|.|  ||.|     .:..|.|.|. |...||   ...|..|.:|   .:
  Rat   821 ------------YEGDTRACLAKRTANGRWSRALISGAQSLEHVRVVFVDYGDKDVVSMK---DI 870

  Fly   384 DPVSTLNFYCAANDFEKPAYNIFNKLRNLHCSVQIAGD---VYSSYP-QEFTD-KETAYQRTAQI 443
            ..||.:.|...|..|....||:          :|..|:   |:.... |.||. .:.|:|...::
  Rat   871 LSVSDVFFKVRAQAFRCSLYNL----------IQPTGENPFVWDERAIQAFTGFIDNAWQNNLEL 925

  Fly   444 AIQRIMHAQSHQK------------LSACTFSDVEFIDGLYKELLKHPHGIL-----GHKLEDWY 491
            .......|..|::            .|||.|        |.::.|..|..:.     ..:|..:|
  Rat   926 KCTIFALASRHEEECFNVVDLLTPFQSACHF--------LVEKRLARPVKLQKPLEPSVQLHSYY 982

  Fly   492 GSTFRQHLPSHWYDLIVKSNK-IRVEHGIDPRIILFANDPGSSEPDRTSITTLPQMVLPWQSSEG 555
            .||         :||.:.|.: :.:.|..||
  Rat   983 YST---------HDLKIGSEELVYITHADDP---------------------------------- 1004

  Fly   556 GSHDWNMFISFCDSTKIVWARMIDQIANFEELTKHIGRQMESPHFRQKVSKPYAQEVYLVEMPDG 620
                |..:.....:|.|:           |:|:.|| .|:.......:.|......:.|.:..||
  Rat  1005 ----WTFYCQLARNTNIL-----------EQLSYHI-MQLSKVLLNLRTSTLVPGTLCLAKYTDG 1053

  Fly   621 WNRVRAISVDEETRSGRYHFIDFGDVAMFHSEDLFHCPP---QFLALPAQAVCLSMYALDKFEDH 682
             |..|.|.:::|  ..:..|:|||:..: .|:.|...|.   ..|.||.|||..|:      .|.
  Rat  1054 -NWYRGIIIEKE--PSKVFFVDFGNTYV-ASDHLLPIPRDAYDVLLLPMQAVKCSL------SDI 1108

  Fly   683 PHALQ-------------------VLTKELDGQTVVA---------------------------- 700
            ||.:.                   |:.|:.||:.::.
  Rat  1109 PHHIPEEVTAWFQETVLDKSLKALVVAKDPDGRLIIELYDESVQINASINEKLGLLGYKNRTRRK 1173

  Fly   701 ----HVLTTEKQFLE-------------LGGS----AQGV-------------------VENGKR 725
                .::..|.:.|:             ||.|    |.||                   ...|..
  Rat  1174 DKENEIILRETETLQDKAEIMKPSPTDYLGKSGDSKAHGVEIMGESCKPKLSPACKELKYLQGSG 1238

  Fly   726 RACLVATLYDTS----------TAEDIHLNDLVAKRITKCTPAPSLSDEKKIGKT---------- 770
            :|.||....|:.          |.|  ...|:.|......|...|...|:::|:.
  Rat  1239 KAHLVTPYQDSMGNKNDGGFLLTRE--KREDMFASSPMSATKLESALPERRMGEASGKDLPPKFC 1301

  Fly   771 ------------TPILVSHINDDGDLMVLLRNDDLKFVERSIAQTVADLGEQDRVSYSDLLHDRH 823
                        |.:.||||||..|..:.|..|:.:.  ..:::.:.|:  :.|..|    |...
  Rat  1302 EFPQKTIAPGFKTSVYVSHINDLSDFYIQLIEDETEI--NRLSERLNDV--RTRPQY----HTGP 1358

  Fly   824 IFVCDETVDGV----KQWFRGRLVTRPLNPDEESFDVYYVDDGRQRKAHISNIYRLEANNRALAT 884
            .:...:.:..|    ..|:|..::.:..|   :...|.::|.|.....|.:...||.
  Rat  1359 PWQSGDVICAVFPEDNLWYRAVVLEQQHN---DLLSVQFIDYGNMSVVHTNRTGRLG-------- 1412

  Fly   885 FPPQAIPVRLHDVPEIGGHMLH-RLRGLIPWRTEALLKVVAMDGGKPLVNVFIREDPESMYMC-- 946
             |..|:      :|.:   .|| .|||::         |..:.|.|.:|..|.:...|:...|
  Rat  1413 -PIDAV------LPAL---CLHCSLRGIV---------VPDIVGTKEMVAYFSQRTDEAQIRCEF 1458

  Fly   947 VNIGLRLELEMASSIHPEKYDHTLLSSNV--QLPRRGSFSSVFSNQSSSSDLVATTPPVTPEKKP 1009
            |......|:.:|.       :|.:::.::  :.|..|...:..:.||...|.          .|.
  Rat  1459 VKFQGTWEVILAD-------EHGIIAEDIINRFPFNGKSQAGLTTQSMKGDC----------SKT 1506

  Fly  1010 SARSTGSTFSSL--------MLKDYEAIPAVGAYFEVRVALSVNPGHFAVQPYKYY-NQLQTLMK 1065
            :.::...|...|        ::|.|..:.....||..:.|.|        :..:|. .::|...|
  Rat  1507 ALKTNMDTSVFLNWYNPKMKLIKAYATVIDGPEYFWCQFADS--------EKLQYVETEVQNAAK 1563

  Fly  1066 NLQEHCQKTAAKGVQPSQLAIGE-AYAAPDSEGVYHRVSIHKIYDE-IIHVRFVDVGD-DGVIAC 1127
            .|.:  :|:..:..|     ||: .......:|.|:|..|..|.|: :..||.||.|: :..:..
  Rat  1564 QLAD--RKSCTQCPQ-----IGDPCIVRYREDGHYYRALITNICDDHLASVRLVDFGNVEDCVDT 1621

  Fly  1128 DQLKTLNPELRKLPKMALPAQLYGIQLT-------------DVVWSKENCVRFRELSLGQKFIGI 1179
            :.|.::..||..:|..|.|..|.|..::             |:|  .|:.:....|.:.:....|
  Rat  1622 NALWSIPSELLLVPMQAFPCCLSGFTVSGGVCPQEGNDYFYDIV--TEDVLEITILEIKRDVCDI 1684

  Fly  1180 VRRMTKQKDGGRAL---CLELVDTSTPKDIKLHEILINEKH 1217
            ...:.:.:..|..:   ..:...|.|||     ..|.:|||
  Rat  1685 PLAVVELRSKGENINEKMKKYAKTGTPK-----SGLYSEKH 1720

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.