Protein Alignment tapas and Tdrd6

DIOPT Version :10

• Sequence 1: NP_611475.3
• Gene: tapas / 37304
• FlyBaseID: FBgn0027529
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_001154838.1
• Gene: Tdrd6 / 210510
• MGIID: 2679727
• Length: 2135
• Species: Mus musculus
• Alignment Length: 770
• Identity: 165/770 - (21%)
• Similarity: 282/770 - (36%)
• Gaps: 200/770 - (25%)

  Fly   530 PGSSEPDRTSITTLPQMVLPWQSSEGGSHDWNMF-------------ISFCDSTKIVWARMIDQI 581
            ||:|...|.|...:...|:|.|.       |.:.             |....:|:..||
Mouse    10 PGASLALRVSFVDVHPEVIPVQL-------WGLVGQRREEYVRLSREIQEAAATRGPWA------ 61

  Fly   582 ANFEELTKHIGRQMESPHFRQKVSKPYAQEVYLVEMPDGWNRVRAISVDEETRSGRYHFID---- 642
                     :|....||           .|:.||::...|:|.|.:|  .:.:..|...:|
Mouse    62 ---------LGGASASP-----------GELCLVQVGLMWHRCRVVS--RQAQDSRVFLLDEGRT 104

  Fly   643 ----FGDVAMFHSEDLFHCPPQFLA------LPA---------------QAVCLSMYALDKFEDH 682
                .|.:|...|| .||.|.:.|.      :||               :||.. :..|...|.|
Mouse   105 ITAGAGSLAPGRSE-FFHLPSEVLGCVLAGLVPAGGGGTGGGEPQQWSPRAVDF-LSNLQGKEVH 167

  Fly   683 PHALQVLTKELDGQTVVAHVLTTEKQFLELGGSAQGVVENGKRRACLVATLYDTSTAEDIHLNDL 747
            ...|.||   |..:.|:..|....:|..|| |.|:.|.::   ..|.:...|.|:..:    ...
Mouse   168 GRVLDVL---LLHRLVLLEVPVVSQQMEEL-GLARQVPDS---LFCSLLKRYLTAAGQ----GSS 221

  Fly   748 VAKRITKCTPA---PSLS---DEKKIGKTTPILVSHINDDGDLMVLLR--NDDLKFVERSIAQTV 804
            .|..:.:..|.   |.|.   .:.::|.|.|::|:.:.....:...||  :.::..:..|:||..
Mouse   222 GAPVLPRAAPKQEHPGLDYFYPQLQLGVTEPVVVTQVCHPHRIHCQLRSLSQEIHRLSESMAQVY 286

  Fly   805 -ADLGEQDRVSYSDLLHDRHIFVCDET------------VDGVKQWFRGRLVT--RPLNPDEESF 854
             |.:|..|..|.|....:|     :|:            :||  ||:|..|:.  ||    :...
Mouse   287 RAPVGTDDEDSGSATWEER-----EESPDKPGSPCASCGLDG--QWYRALLLETFRP----QRCA 340

  Fly   855 DVYYVDDGRQRKAHISNI-YRLEANNRALATFPPQAIPVRLHDVPEIGGHMLHRLRGLIPWRTEA 918
            .|.:||.||:.....|:: |.|....|    .|....|..|:.:.:.|       ||   |....
Mouse   341 QVLHVDYGRKELVSCSSLRYLLPEYFR----MPVVTYPCALYGLWDCG-------RG---WSRSQ 391

  Fly   919 LLKVVAMDGGKPLVNVFIRE--DPESMYMC-------VNIGLRLELEMASSIHPEKYDHTLLSSN 974
            :..:.|:..|: .||..|..  ..|.||..       :|:.....::.....     |..|.|..
Mouse   392 VGDLKALILGQ-AVNAKIEFYCSFEHMYYVTLYGEDGINLNSAFGVQSCCLA-----DWFLQSQG 450

  Fly   975 VQLPR---RGSFSSVFSNQSSSSDLVATTPPVTPEKKPSARSTGSTFSSLMLKDYEAIPAVGAYF 1036
            ::...   .....:.|.:||.:.::.|..      ..||.|       |:.||       :..::
Mouse   451 IEEEEEEDEDEVEAAFQSQSPAEEMEAEV------SLPSLR-------SIRLK-------MNTFY 495

  Fly  1037 EVRVALSVNPGHFAVQPYKYYNQLQTLMKNLQEHCQ--KTAAK--GV----QPSQLAIGEAYAAP 1093
            :.:|....:|..|.::..|:.|....|.|.:   |.  .:|:|  ||    :|..|.     ...
Mouse   496 DAQVEFVKSPSEFWIRLRKHKNTFSKLTKRM---CSFYSSASKLDGVILRPEPDDLC-----CVK 552

  Fly  1094 DSEGVYHRVSIHKIYDEIIHVRFVDVGD-DGVIACDQLKTLNPELRKLPKMALPAQLYGIQLTDV 1157
            ..|..|:|.::.::..:.:.|..||.|: :.|..|| ::.|.|:.|:||.:||...|..|.....
Mouse   553 WKENGYYRATVTRLDSKSVDVFLVDRGNSENVDWCD-VRMLLPQFRQLPILALKCTLADIWPLGK 616

  Fly  1158 VWSKENCVRFRELSLGQKFIGIVRRMTKQKDGGRALCLELVDTSTPKDIKLHEIL 1212
            .||:|....|::..|.::.  :|..:.||   .....:|::|.|...:..:.:::
Mouse   617 TWSQEATSFFKKTVLHKEL--VVHVLDKQ---DHQYVIEILDESRMGEENISKVI 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tapas	NP_611475.3	LOTUS_TDRD_OSKAR	7..92	CDD:193586
		TUDOR	563..673	CDD:425754	28/151 (19%)
		TUDOR	769..896	CDD:425754	35/144 (24%)
		TUDOR	1034..1151	CDD:425754	32/125 (26%)
Tdrd6	NP_001154838.1	Tudor_TDRD6_rpt1	6..136	CDD:410491	33/161 (20%)
		Tudor_TDRD6_rpt2	239..379	CDD:410492	36/154 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..315		7/32 (22%)
		Tudor_SF	494..628	CDD:470623	37/142 (26%)
		Tudor_SF	771..891	CDD:470623
		Tudor_SF	980..1104	CDD:470623
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1271..1296
		Tudor_SF	1312..1426	CDD:470623
		Tudor_SF	1524..1666	CDD:470623
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1699..1733
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1860..1885
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1930..1985