DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CkIIbeta2 and kin-10

DIOPT Version :9

Sequence 1:	NP_477407.1	Gene:	CkIIbeta2 / 37300	FlyBaseID:	FBgn0026136	Length:	219	Species:	Drosophila melanogaster
Sequence 2:	NP_001379151.1	Gene:	kin-10 / 172610	WormBaseID:	WBGene00002196	Length:	235	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	126/226 - (55%)
Similarity:	158/226 - (69%)	Gaps:	16/226 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTDSDESSWIHWFCKQRGNEFFCEVDEEYIQDKFNLNFLDSNVKNYKCALEVILDLNPGSASEDP 65
            |:.|:|.|||.|||..||||||||||||||||:|||..|:..|..|:.||::||||.|....||.
Worm     1 MSSSEEVSWITWFCGLRGNEFFCEVDEEYIQDRFNLTGLNEQVPKYRQALDMILDLEPEDDIEDN 65

  Fly    66 AEPE--LEASAEKLYGLIHARFILTNRGIELMLDKYNKGEFGTCPRAFCHSQPVLPIGLSDNPGE 128
            |...  :|.:||.||||||||:|||||||..|::|:...:||.|||.:|.:||:|||||||.|||
Worm    66 ATNTDLVEQAAEMLYGLIHARYILTNRGISQMVEKWRDHDFGVCPRVYCENQPMLPIGLSDVPGE 130

  Fly   129 DMVRIYCPKCNDVYIPKASRHSNLDGAFFGTGFPHMFFMEKPDARPKRAKQKFVPRLYGFKIHPT 193
            .||::|||:||||::|::|||.:.||::||||||||.|...||.||:|...:|||:||||||||.
Worm   131 AMVKLYCPRCNDVFVPRSSRHQHTDGSYFGTGFPHMLFFVHPDLRPRRPVTQFVPKLYGFKIHPV 195

  Fly   194 AY------------RTAAEIQKDVTMTPVGE 212
            ||            ...|..|.:.  ||.|:
Worm   196 AYGGQEGNSGGNTANNVAAAQNNT--TPAGQ 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CkIIbeta2	NP_477407.1	CK_II_beta	9..189	CDD:279546	110/181 (61%)
kin-10	NP_001379151.1	CK_II_beta	8..191	CDD:198153	111/182 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.772836	Normalized mean entropy	S292
OMA	1	1.010	-	-		QHG53662
OrthoDB	1	1.010	-	-		D1335521at2759
OrthoFinder	1	1.000	-	-		FOG0001997
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100687
Panther	1	1.100	-	-	O	PTHR11740
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1673
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.880