Protein Alignment Kpc2 and UBAC1

DIOPT Version :10

• Sequence 1: NP_001261098.1
• Gene: Kpc2 / 37261
• FlyBaseID: FBgn0028372
• Length: 561
• Species: Drosophila melanogaster
• Sequence 2: NP_057256.2
• Gene: UBAC1 / 10422
• HGNCID: 30221
• Length: 405
• Species: Homo sapiens
• Alignment Length: 368
• Identity: 100/368 - (27%)
• Similarity: 172/368 - (46%)
• Gaps: 49/368 - (13%)

  Fly   197 DDPDSIQLFAPDVRHLNPRYRLYRAEYFGGE--LNEGDTLAQLKVRNNETFILSPRR--NTLPQT 257
            :||.||           ..::|..|   ..|  |::..|:.:..:::.:..:|..:|  :.||:.
Human    53 EDPKSI-----------THHKLIHA---ASERVLSDARTILEENIQDQDVLLLIKKRAPSPLPKM 103

  Fly   258 V------SRIREVPGPNEQLVESATRYVPVNCNQLPTIDINEIFQQSNI---QYDVRKVLISLAQ 313
            .      .:.::...|:::.:..||.       .||:.:::....|:|:   |.::||:|:||.:
Human   104 ADVSAEEKKKQDQKAPDKEAILRATA-------NLPSYNMDRAAVQTNMRDFQTELRKILVSLIE 161

  Fly   314 ASAAVIGAGPYAPRLIAMLKQRLINRRNQQAD--TLQCLVDMGFKRELAAFALKAHNGIYSTTME 376
            .:..::...|.|..|.......|....:::.|  .|:.|.:|||....|..||:.::......||
Human   162 VAQKLLALNPDAVELFKKANAMLDEDEDERVDEAALRQLTEMGFPENRATKALQLNHMSVPQAME 226

  Fly   377 WLIQNQNE---------ENPQEPPGMNMQHSLSSISPSTIVTNNETIENTAALIEIVRIYSHRDS 432
            |||::..:         :.|.|..|.....|.::...|  .|:.|..:....:.:.:|  ..|:.
Human   227 WLIEHAEDPTIDTPLPGQAPPEAEGATAAASEAAAGAS--ATDEEARDELTEIFKKIR--RKREF 287

  Fly   433 PPSDEIVESLTEMGFEETAVLAALKKTGNNKASACEWLCDNRSGSVIELREGLAPDSPILKVILE 497
            ......|.||.||||:|..|:.||:...|.:.:|||||..:|..|..||.:|:.||||:.:.||:
Human   288 RADARAVISLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDKGIDPDSPLFQAILD 352

  Fly   498 MPQVQMTLSNPKTFLAFLGILENEHAIRVWRGDNDTTSVITHI 540
            .|.||:.|:||||.|||..:|||......|..|.:|..|:..|
Human   353 NPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQI 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kpc2	NP_001261098.1	UBA_like_SF	345..384	CDD:473871	14/40 (35%)
		UBA2_KPC2	434..472	CDD:270489	17/37 (46%)
UBAC1	NP_057256.2	Ubl_KPC2	9..95	CDD:340586	10/55 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..120		1/18 (6%)
		UBA1_KPC2	195..232	CDD:270488	13/36 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	235..271		7/37 (19%)
		UBA2_KPC2	290..327	CDD:270489	17/36 (47%)
		STI1	353..392	CDD:128966	17/38 (45%)