Protein Alignment Rep and rep-1

DIOPT Version :9

• Sequence 1: NP_477420.1
• Gene: Rep / 37246
• FlyBaseID: FBgn0026378
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001022928.1
• Gene: rep-1 / 175311
• WormBaseID: WBGene00022051
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 514
• Identity: 155/514 - (30%)
• Similarity: 251/514 - (48%)
• Gaps: 45/514 - (8%)

  Fly     1 MLDDLPEQFDLVVIGTGFTESCIAAAGSRIGKSVLHLDSNEYYGDVWSSFSMDAL-------CAR 58
            |.:.|||..|:||:|||..|:.:|:|.:|.|.||||||.|||||..||||:|..:       ..:
 Worm     1 MDEKLPESVDVVVLGTGLPEAILASACARAGLSVLHLDRNEYYGGDWSSFTMSMVHEVTENQVKK 65

  Fly    59 LDQ-----------------EVEPHSALRNARYTWHSMEKESETDAQSWNRDSVLAKSRRFSLDL 106
            ||.                 |:.....:.|...||....|:.|...::...::  ::.||||:||
 Worm    66 LDSSEISKLSELLTENEQLIELGNREIVENIEMTWIPRGKDEEKPMKTQLEEA--SQMRRFSIDL 128

  Fly   107 CPRILYAAGELVQLLIKSNICRYAEFRAVD-HVCMRHNGE----IVSVPCSRSDVFNTKTLTIVE 166
            .|:||.:.|.:||.|..|.:..||||:.|: .:|.....|    :..||||:.::|.:..|:|:|
 Worm   129 VPKILLSKGAMVQTLCDSQVSHYAEFKLVNRQLCPTETPEAGITLNPVPCSKGEIFQSNALSILE 193

  Fly   167 KRLLMKFLTACNDYGEDKCNEDS---LEFRGRTFLEYLQAQRVTEKISSCVMQAIAMCGPSTSFE 228
            ||.||||:|.|..:......|..   .|...|.|.|:|:...|.:.:.|.::..|.:.....:..
 Worm   194 KRALMKFITFCTQWSTKDTEEGRKLLAEHADRPFSEFLEQMGVGKTLQSFIINTIGILQQRPTAM 258

  Fly   229 EGMQRTQRFLGSLGRYGNTPFLFPMYGCGELPQCFCRLCAVYGGIYCLKRAVDDIALDSNSNEFL 293
            .||..:.:|:.|:|.:|.:|||||:||||||.||||||.||:|.:|||.|.|..|.........:
 Worm   259 TGMLASCQFMDSVGHFGPSPFLFPLYGCGELSQCFCRLAAVFGSLYCLGRPVQAIVKKDGKITAV 323

  Fly   294 LSSAGKTLRAKNVVSAPGYTPVSKGIELKPHISRGLFISSSPLGNEELNKGGGGVNLLRLLD-NE 357
            ::: |..:..:.:|.:|.:.|.:........|.|.::.:...:...|..:    :.||.|.. ..
 Worm   324 IAN-GDRVNCRYIVMSPRFVPETVPASSTLKIERIVYATDKSIKEAEKEQ----LTLLNLASLRP 383

  Fly   358 GGREAFLIQLSHYTGACPEGLYIFHLTTPALSEDPASDLAIFTSQLFDQSDAQIIFSSYFTIAAQ 422
            ....:.|:::.......|:|.::.|.|.....|.....:|   .::|::::.:..:...||..:.
 Worm   384 DAAVSRLVEVGFEACTAPKGHFLVHATGTQEGETSVKTIA---EKIFEKNEVEPYWKMSFTANSM 445

  Fly   423 SSKSPAAEHIYYTDPPTYELDYDAAIANARDIFGKMFPDADFLPRAPDPEEIVVDGEDP 481
            ...:..||::....|....|.|.:.:...|.:|...:|:.||||||...||  .:.|:|
 Worm   446 KFDTAGAENVVVAPPVDANLHYASVVEECRQLFCTTWPELDFLPRAMKKEE--EEEEEP 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rep	NP_477420.1	NADB_Rossmann	4..397	CDD:304358	132/425 (31%)
rep-1	NP_001022928.1	NADB_Rossmann	1..>361	CDD:304358	123/362 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161759
Domainoid	1	1.000	171	1.000	Domainoid score	I2257
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I2116
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54506
OrthoDB	1	1.010	-	-		D1017439at2759
OrthoFinder	1	1.000	-	-		FOG0004306
OrthoInspector	1	1.000	-	-		oto17345
orthoMCL	1	0.900	-	-		OOG6_103227
Panther	1	1.100	-	-	LDO	PTHR11787
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3039
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.910