Protein Alignment Rep and rep-1

DIOPT Version :10

• Sequence 1: NP_477420.1
• Gene: Rep / 37246
• FlyBaseID: FBgn0026378
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001022928.1
• Gene: rep-1 / 175311
• WormBaseID: WBGene00022051
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 517
• Identity: 155/517 - (29%)
• Similarity: 250/517 - (48%)
• Gaps: 53/517 - (10%)

  Fly     1 MLDDLPEQFDLVVIGTGFTESCIAAAGSRIGKSVLHLDSNEYYGDVWSSFSMDAL-------CAR 58
            |.:.|||..|:||:|||..|:.:|:|.:|.|.||||||.|||||..||||:|..:       ..:
 Worm     1 MDEKLPESVDVVVLGTGLPEAILASACARAGLSVLHLDRNEYYGGDWSSFTMSMVHEVTENQVKK 65

  Fly    59 LDQ-----------------EVEPHSALRNARYTWHSMEKESETDAQSWNRDSVLAKSRRFSLDL 106
            ||.                 |:.....:.|...||....|:.|...::...::  ::.||||:||
 Worm    66 LDSSEISKLSELLTENEQLIELGNREIVENIEMTWIPRGKDEEKPMKTQLEEA--SQMRRFSIDL 128

  Fly   107 CPRILYAAGELVQLLIKSNICRYAEFRAVD-HVCMRHNGE----IVSVPCSRSDVFNTKTLTIVE 166
            .|:||.:.|.:||.|..|.:..||||:.|: .:|.....|    :..||||:.::|.:..|:|:|
 Worm   129 VPKILLSKGAMVQTLCDSQVSHYAEFKLVNRQLCPTETPEAGITLNPVPCSKGEIFQSNALSILE 193

  Fly   167 KRLLMKFLTACNDYGEDKCNEDS---LEFRGRTFLEYLQAQRVTEKISSCVMQAIAMCGPSTSFE 228
            ||.||||:|.|..:......|..   .|...|.|.|:|:...|.:.:.|.::..|.:.....:..
 Worm   194 KRALMKFITFCTQWSTKDTEEGRKLLAEHADRPFSEFLEQMGVGKTLQSFIINTIGILQQRPTAM 258

  Fly   229 EGMQRTQRFLGSLGRYGNTPFLFPMYGCGELPQCFCRLCAVYGGIYCLKRAVDDIALDSNSNEFL 293
            .||..:.:|:.|:|.:|.:|||||:||||||.||||||.||:|.:|||.|.|..|.........:
 Worm   259 TGMLASCQFMDSVGHFGPSPFLFPLYGCGELSQCFCRLAAVFGSLYCLGRPVQAIVKKDGKITAV 323

  Fly   294 LSSAGKTLRAKNVVSAPGYTPVSKGIELKPHISRGLFISSSPLGNEELNKGGGGVNLLRLLD-NE 357
            ::: |..:..:.:|.:|.:.|.:........|.|.::.:...:...|..:    :.||.|.. ..
 Worm   324 IAN-GDRVNCRYIVMSPRFVPETVPASSTLKIERIVYATDKSIKEAEKEQ----LTLLNLASLRP 383

  Fly   358 GGREAFLIQLSHYTGACPEGLYIFHLTTPALSEDPASDLAIFTSQLFDQSDAQIIFSSYFTIAAQ 422
            ....:.|:::.......|:|.::.|.|.....|.....:|   .::|::::.:..:...||..:.
 Worm   384 DAAVSRLVEVGFEACTAPKGHFLVHATGTQEGETSVKTIA---EKIFEKNEVEPYWKMSFTANSM 445

  Fly   423 SSKSPAAEHIYYTDPPTYELDYDAAIANARDIFGKMFPDADFLPRA----------PDPEEI 474
            ...:..||::....|....|.|.:.:...|.:|...:|:.||||||          |:.|||
 Worm   446 KFDTAGAENVVVAPPVDANLHYASVVEECRQLFCTTWPELDFLPRAMKKEEEEEEEPETEEI 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rep	NP_477420.1	Rossmann-fold NAD(P)(+)-binding proteins	4..397	CDD:473865	132/425 (31%)
rep-1	NP_001022928.1	Rossmann-fold NAD(P)(+)-binding proteins	1..>361	CDD:473865	123/362 (34%)