DRSC/TRiP Functional Genomics Resources

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Protein Alignment CalpA and sol

DIOPT Version :10

Sequence 1:NP_001286613.1 Gene:CalpA / 37232 FlyBaseID:FBgn0012051 Length:843 Species:Drosophila melanogaster
Sequence 2:XP_061517637.1 Gene:sol / 4576096 VectorBaseID:AGAMI1_014806 Length:1311 Species:Anopheles gambiae


Alignment Length:470 Identity:131/470 - (27%)
Similarity:212/470 - (45%) Gaps:105/470 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 QPLQSQSNSTLYYGNLGEKSSSLGPYSEVQDYETILNSCLASGSLFEDPLFPASNESLQFSRRPD 123
            |.|| |||      .|.|....|.....:..:::|:..|:.:|..|.|..||.:.:||.:  :|.
Mosquito   692 QQLQ-QSN------RLEENQRQLDDLEALNRWKSIIEYCVENGQAFVDDSFPPAMKSLYY--QPS 747

  Fly   124 RHIE------WLRPHEI-------AENPQFFVEGYSRF------DVQQGELGDCWLLAATANLTQ 169
            .:||      |.||:||       :..||:.|     |      |:.||.||:||||:|.|.|.:
Mosquito   748 SNIECNPVAQWRRPNEILCEGGNQSTAPQWAV-----FRTPLPSDICQGVLGNCWLLSALAVLAE 807

  Fly   170 ESNLFFRVIPAEQSFEENYAGIFHFRFWQYGKWVDVIIDDRLP-TYNGELMYMHSTEKNEFWSAL 233
            ..:|...|:..::...:   |.:..:..:.|:|..|::||.|| ...|.|:|..:..| :.|..|
Mosquito   808 REDLVKEVLLTKEICPQ---GAYQVKLCKDGRWTTVLVDDLLPCDKRGHLVYSQAKRK-QLWVPL 868

  Fly   234 LEKAYAKLHGSYEALKGGSTCEAMEDFTGGVSEWYDLKEA----PGN-------LFTILQKAAER 287
            :|||.||:||.||||..|...|.:...||...|...|:.:    |..       ::..|..:...
Mosquito   869 IEKAVAKIHGCYEALVSGRAIEGLATLTGAPCESIPLQASSLPLPSEDDLDRDLIWAQLLSSRLV 933

  Fly   288 NSMMGCSI-EPDPNVTEAE-TPQGLIRGHAYSITKVCLIDI--VTPNRQGKIPMIRMRNPWGNEA 348
            ..:||.|. ..:..|.|.| ..:||...||||:     :|:  :..:|     ::::|||||: .
Mosquito   934 KFLMGASCGGGNMKVDEDEYQRKGLRPRHAYSV-----LDVRDIKGHR-----LLKLRNPWGH-F 987

  Fly   349 EWNGPWSDSSPEWRYIPEEQKAEIGLTFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQNS 413
            .|.|.|||.|..|   .:|.:..:......:|.||:||:|.|.:||.::||.:            
Mosquito   988 SWQGDWSDDSELW---TDELRDSLMPHGGSEGVFWISFEDVLRYFDCIDICKV------------ 1037

  Fly   414 GKRKWEMSMYEGEWTPGVTAGGCRNFLDTFWHNPQYIITLVDPDEED----EEGQCTVIVALMQK 474
             :.:|......|...| :.|..|            .:||:::|.|.:    :|||..     .:|
Mosquito  1038 -RSEWNEVRLFGTLQP-LRALSC------------VLITVLEPTEAEFTLFQEGQRN-----SEK 1083

  Fly   475 NRRSKRNMGMECLTI 489
            ::||:.::   |:.:
Mosquito  1084 SQRSQLDL---CVVL 1095

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CalpANP_001286613.1 Peptidase_C2 104..400 CDD:459889 102/330 (31%)
Calpain_III 416..569 CDD:238132 16/78 (21%)
EFh_PEF_CalpA_B 600..843 CDD:320071
EF-hand motif 600..627 CDD:320071
EF-hand motif 717..747 CDD:320071
EF-hand motif 748..778 CDD:320071
EF-hand motif 784..812 CDD:320071
EF-hand motif 813..843 CDD:320071
solXP_061517637.1 None
Blue background indicates that the domain is not in the aligned region.

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