Protein Alignment hts and add2

DIOPT Version :10

• Sequence 1: NP_001097377.2
• Gene: hts / 37230
• FlyBaseID: FBgn0263391
• Length: 1833
• Species: Drosophila melanogaster
• Sequence 2: NP_001096433.1
• Gene: add2 / 100125042
• XenbaseID: XB-GENE-986535
• Length: 586
• Species: Xenopus tropicalis
• Alignment Length: 613
• Identity: 225/613 - (36%)
• Similarity: 332/613 - (54%)
• Gaps: 70/613 - (11%)

  Fly     4 VEQPP---QNGIDPTAGEDDDNSKAR--PADIEQDMREMERRKRVEAIMGSKLFREELERIVDSA 63
            |..||   |...|....:|.:..:.|  .||:.||...||::|||..|:.|..||||||.::...
 Frog    10 VSSPPPQEQKYFDRYTEDDPEYLRVRNMAADLRQDFNVMEQKKRVSMILQSPSFREELESLIQEQ 74

  Fly    64 RDGGAGASGI--LQQLSDIVGVPVSRVGSVFK----SSNCMVPINDIRGVESMGYAKGEKILRCK 122
            ...|..:|.|  |:|::|.:   .|...|||.    ||:.::|||||...:.:..||||:::|||
 Frog    75 MKKGNNSSNIWALRQIADFM---ASTAPSVFPTCPVSSSMVLPINDIHCNDPIPLAKGERLMRCK 136

  Fly   123 LAATFRLLDLYGWTQGLGAQITARLKVDQEYFLVNPYGLLYHEITASALNKVDMQGQIVEQGTTN 187
            ||:.:||:|||||.|..|...:.|:..:|::||::|.|:..:|:|||:|.||::.|:.||.|:|:
 Frog   137 LASVYRLMDLYGWAQLSGTFASIRVNKEQDHFLISPRGISCNEVTASSLVKVNILGETVELGSTS 201

  Fly   188 FGGNKSHFVLHSVVHAARPDIRCAIYIGCSPVVAISSLKTGLLPLTKDACVLGEITTHAYTGLFD 252
            |......|.|||.:::||||:||.|.:..:...|:|::|.||||::.||.:.||:..:.|:|..:
 Frog   202 FEVASCDFSLHSAIYSARPDVRCIIQLHTAAATAVSAMKCGLLPISHDALLAGEVMYYEYSGDME 266

  Fly   253 -EEERNRLVRSLGPNSKVILLTNHGALCCGETIEEAFFAACHIVQACETQLKLLPV--GLDNLVL 314
             |::|..|.:.|||..|:::|.|||.:..|||:||||:...|:..|||.|:..:|.  |.|||:|
 Frog   267 AEDDRIELQKCLGPTCKILILQNHGVVALGETVEEAFYKIFHLQAACEIQVSAVPSAGGPDNLIL 331

  Fly   315 IPEESRKAIYEQSRRPPEDLEKKFAAVAAAEDGAATAEKDAAEAVPKVGSPPKWRVGGAEFEALM 379
            :..|        ..||.|               ..|    ...|..|.|...|.|:|..||||||
 Frog   332 LDRE--------KYRPHE---------------VGT----VGWAGSKFGPMQKSRLGEHEFEALM 369

  Fly   380 RMLDNAGYRTGYIYRHPLIKSDPPKPKNDVELPPAVSSLGYLLEEE----ELFRQGIWKKGDIRK 440
            ||:||.||||||.||||.:: :..:.|::||:|..|::  :|.|||    ...||...|:..
 Frog   370 RMMDNLGYRTGYSYRHPFVQ-EKTRHKSEVEIPATVTA--FLFEEEGVPISTLRQHAQKQQK--- 428

  Fly   441 GGDRSRWLNSPNVYQKVEVLETGTPDPKKITKWVAEG---SPTHSTPVRIEDPLQFVPAGTNPRE 502
              :::||||:||.|.:|.|.|.....|:..|.|:...   .|:....:|||:..||||..|:|||
 Frog   429 --EKTRWLNTPNTYLRVNVAEDNVGSPRSKTTWLKADEVVKPSSGIAIRIENSNQFVPLFTDPRE 491

  Fly   503 FKRVQQLIKDNRRADKISAGPQSHILEGVTWDEASRLKDATVSQAGDHVVMMGAASKGIIQRGFQ 567
            ....:..|::..|.|..||||||.:|..|       :.|.:.|.:.|..:    ||:...:...:
 Frog   492 VLETRNKIREQNRQDFKSAGPQSQLLANV-------ITDKSRSPSADSQL----ASRTEAEMKQE 545

  Fly   568 HNATVYKAPYAKNPFDNVTDDELNEYKR 595
            ....|...|...|||..:||.||....|
 Frog   546 PLEDVSPEPEPPNPFSQLTDQELEARPR 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hts	NP_001097377.2	Aldolase_II	116..323	CDD:238232	88/209 (42%)
add2	NP_001096433.1	Aldolase_II	130..340	CDD:469663	89/217 (41%)