Protein Alignment CG10081 and ERMP1

DIOPT Version :10

• Sequence 1: NP_611418.1
• Gene: CG10081 / 37226
• FlyBaseID: FBgn0034441
• Length: 875
• Species: Drosophila melanogaster
• Sequence 2: NP_079172.2
• Gene: ERMP1 / 79956
• HGNCID: 23703
• Length: 904
• Species: Homo sapiens
• Alignment Length: 879
• Identity: 268/879 - (30%)
• Similarity: 438/879 - (49%)
• Gaps: 105/879 - (11%)

  Fly    49 LFIAVVKPLFYRLPEPLTVEDAS--KGGFIAERAQANLYDFEAIGTKVVGSDENEHKTVQFLLKE 111
            |::..::.|.....:.|.:..|:  :|.|.|.:|:..|....:||.:..||.|||..||.:||::
Human    79 LYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQ 143

  Fly   112 LNLIKDNIQED-LFDMEIDLQYAYGAY---VKWNLVNMYQGIQNVVVKLTPKGTTSENYILVNSH 172
            :.||:  :|.: |..:.:|:|...|::   ......:.|..|.||||||.|: ..:::.:|.|.|
Human   144 IKLIE--VQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPR-DGAQHAVLANCH 205

  Fly   173 FDSQPTSPSTGDDGHMVVSILEVLRVISSRRKSFEHPIIFLINGSEENSLQASHGFIAYHKWAKN 237
            |||...||...||......:||||||:|:..::..|.:|||.||:|||.||||||||..|.||..
Human   206 FDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASL 270

  Fly   238 CKAVINLDAAGSGGRELMFQSGPNNPWLVKIYKDGAKHYFSTTMAEEIFQTGLVPSYTDFDIFVE 302
            .:|.|||:|||.||:||:||:||.|||||:.|...|||.|::.:|:|:||:|::||.|||.|:.:
Human   271 IRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRD 335

  Fly   303 YGNLIGLDIGQCINGFVYHTKYDRIDVIPRAALQNTGDNLLGLVQTLSNASELRDLSANPTGNTI 367
            :||:.|:|:....||::||||||..|.|...::|..|||:|.:::.|:.:..|...|....||.:
Human   336 FGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKHLATSDMLAAASKYRHGNMV 400

  Fly   368 FFDVLGLYLISYSADVGVKLNYAVAAAAIILIYISLLRIAEKSSVSSEQILSTFILVLVVQLIAF 432
            |||||||::|:|.:.:|..:||.|....::.:....|:...|:.    .....|:..|.:.||::
Human   401 FFDVLGLFVIAYPSRIGSIINYMVVMGVVLYLGKKFLQPKHKTG----NYKKDFLCGLGITLISW 461

  Fly   433 VLALALPLLVAYGLDKYGLSLSYFATPSLLIGLY----ICPSLLGLTLPSYIYLKLANTE---KV 490
            ..:|...|::|..:...|.|||::....:.:.||    :...:|..||....|...|:.:   :|
Human   462 FTSLVTVLIIAVFISLIGQSLSWYNHFYVSVCLYGTATVAKIILIHTLAKRFYYMNASAQYLGEV 526

  Fly   491 SFAQQVQLALHGHAAVLSILCIAINYYGLRTTYV-ITWTLAFYVIPLAFNLLTTL--------HD 546
            .|    .::|..|...|    :.:.|.||.:.:: ..|        :||.|||.|        |.
Human   527 FF----DISLFVHCCFL----VTLTYQGLCSAFISAVW--------VAFPLLTKLCVHKDFKQHG 575

  Fly   547 RGYSWTGILKIVQVAPFMYNSYLFYCFIVILTPMMGRFGVDTNPDLIIGALTALGT-ILSMGFL- 609
            ....:.....:....|::|..||.:....:.||::||.|.:..||:::.::.|..| |||..|:
Human   576 AQGKFIAFYLLGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTMILSSYFIN 640

  Fly   610 -ILLVNMSRRSGFVLIGLLAVT----AAGVYIASSTDIGFPYRPKTNVQRVPYLQVRRIFYEYDG 669
             |.|...::::...|..:.|:|    .:|.:...|::   |..||.  :||....:.|.|::.:|
Human   641 FIYLAKSTKKTMLTLTLVCAITFLLVCSGTFFPYSSN---PANPKP--KRVFLQHMTRTFHDLEG 700

  Fly   670 TVSKDESGYLFNLQDRRG---LTPLLESNVDLTGLVNMTSDCAKYM-MCGMPLYDHRWVEAMETT 730
            ...|.:||...|..|..|   :||.:....|     ::.:.|.:.. :||.|.|
Human   701 NAVKRDSGIWINGFDYTGISHITPHIPEIND-----SIRAHCEENAPLCGFPWY----------- 749

  Fly   731 MWLP-----RKN-----PVWTPAEPILKQLNKTVLADGQTVQFEFELTTSDHTSIFISPNEDVII 785
              ||     |||     |..:|..|...:|.........:::..||.|...|.|.::..::...:
Human   750 --LPVHFLIRKNWYLPAPEVSPRNPPHFRLISKEQTPWDSIKLTFEATGPSHMSFYVRAHKGSTL 812

  Fly   786 SNWSFLK-EYLTTNSPPYHIYYSFGIDNTPLRFHIELKKA----DGVYTVPLFQMGIGAHYMHVK 845
            |.||... ..:|:....|.::||.|:..:..:|.||::.:    :|:.||     .|.|||:  .
Human   813 SQWSLGNGTPVTSKGGDYFVFYSHGLQASAWQFWIEVQVSEEHPEGMVTV-----AIAAHYL--S 870

  Fly   846 GDDESI----RLANSLPDYAVSIQWPAMYKKYIF 875
            |:|:..    .|....||:.....|...|..::|
Human   871 GEDKRSPQLDALKEKFPDWTFPSAWVCTYDLFVF 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10081	NP_611418.1	M28_Fxna_like	72..379	CDD:349872	137/310 (44%)
ERMP1	NP_079172.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..65
		M28_Fxna_like	104..412	CDD:349872	137/310 (44%)