Protein Alignment CG10081 and CPQ

DIOPT Version :10

• Sequence 1: NP_611418.1
• Gene: CG10081 / 37226
• FlyBaseID: FBgn0034441
• Length: 875
• Species: Drosophila melanogaster
• Sequence 2: NP_057218.1
• Gene: CPQ / 10404
• HGNCID: 16910
• Length: 472
• Species: Homo sapiens
• Alignment Length: 459
• Identity: 90/459 - (19%)
• Similarity: 162/459 - (35%)
• Gaps: 129/459 - (28%)

  Fly    38 FAGGIVLFWALLFIAVVK-PLFYRLPEPLTVEDASKGGF--------IAERAQANLYD-----FE 88
            |.||:.|.......|:.| .:..|..|.:..|.||.|..        :..:||...|:     .:
Human     8 FFGGVHLLSLCSGKAICKNGISKRTFEEIKEEIASCGDVAKAIINLAVYGKAQNRSYERLALLVD 72

  Fly    89 AIGTKVVGSDENEHKTVQFLLKELNLIKDNIQEDLFDMEIDLQYAYGAYVKWNLVNMYQGIQNVV 153
            .:|.::.|| :|..|.:|.:.:       |:|:|..: ::.|:..       .:.:..:|.::.|
Human    73 TVGPRLSGS-KNLEKAIQIMYQ-------NLQQDGLE-KVHLEPV-------RIPHWERGEESAV 121

  Fly   154 -----------------VKLTPKGTTSENYILVNSHFDSQPTSPSTGDDGHMVV---SILEVLRV 198
                             :...|:|.|:|  :||.:.||......|.. .|.:||   ..:...|.
Human   122 MLEPRIHKIAILGLGSSIGTPPEGITAE--VLVVTSFDELQRRASEA-RGKIVVYNQPYINYSRT 183

  Fly   199 ISSRRKSFEH-----PIIFLINGSEENSLQASH-GFIAYHKWA-KNCKAVINLDAAGSGGRELMF 256
            :..|.:....     .:..||......|:.:.| |...|.... |...|.|.::.|     |:|.
Human   184 VQYRTQGAVEAAKVGALASLIRSVASFSIYSPHTGIQEYQDGVPKIPTACITVEDA-----EMMS 243

  Fly   257 QSGPNNPWLVKIYKDGAKHYFST----TMAEEIFQTGLVPSYTDFDIFVEYGNLIGLDIGQCING 317
            :...:...:|...|.|||.|..|    |:||   .||  ..|.:..:.|. |:|...|:||
Human   244 RMASHGIKIVIQLKMGAKTYPDTDSFNTVAE---ITG--SKYPEQVVLVS-GHLDSWDVGQ---- 298

  Fly   318 FVYHTKYDRIDVIPRAALQNTGDNLLGLVQTLSNASELRDLSANP----------------TGNT 366
                           .|:.:.|    |...:....|.::||...|                .|..
Human   299 ---------------GAMDDGG----GAFISWEALSLIKDLGLRPKRTLRLVLWTAEEQGGVGAF 344

  Fly   367 IFFDVLGLYLISYS----ADVGVKLNYAVAAAAIILIYISLLRIAEKSSVSSEQILSTFILVLVV 427
            .::.:..:.:.:||    :|.|..|...:....           :||:....|:::|....:.:.
Human   345 QYYQLHKVNISNYSLVMESDAGTFLPTGLQFTG-----------SEKARAIMEEVMSLLQPLNIT 398

  Fly   428 QLIA 431
            |:::
Human   399 QVLS 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10081	NP_611418.1	M28_Fxna_like	72..379	CDD:349872	69/366 (19%)
CPQ	NP_057218.1	M28_Pgcp_like	42..449	CDD:349879	80/425 (19%)