Protein Alignment CG10062 and ERMP1

DIOPT Version :10

• Sequence 1: NP_001261089.1
• Gene: CG10062 / 37224
• FlyBaseID: FBgn0034439
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: NP_079172.2
• Gene: ERMP1 / 79956
• HGNCID: 23703
• Length: 904
• Species: Homo sapiens
• Alignment Length: 862
• Identity: 270/862 - (31%)
• Similarity: 438/862 - (50%)
• Gaps: 59/862 - (6%)

  Fly    32 LVLYLSLVNTQMNHMPRPLTRSDEASHPNSFIAQRAEDTLIELTRIGPRVVGSMANEESAVEFLR 96
            |.|||..:.|.:....:.|.....|.|...|.|.:|.|.|..:|.||||..||..||...|.:|.
Human    77 LALYLIALRTLVQLSLQQLVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLL 141

  Fly    97 AEVAKVESEMSDLLEIEVDVQQASGAY---MHWEMVNMYQGIQNVVVKLSEKNSTNENYLLINSH 158
            .::..:|.:.:.|.:|.||||:.:|::   ......:.|..|.||||||..::.. ::.:|.|.|
Human   142 EQIKLIEVQSNSLHKISVDVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRDGA-QHAVLANCH 205

  Fly   159 YDSVPGSPGAGDDGSMVVTMLEVMRVIAKSGDPLAHPIVFLFNGAEENPLQASHAFITQHKWAKN 223
            :|||..||||.||......||||:||::.|.:.|.|.::|||||||||.|||||.|||||.||..
Human   206 FDSVANSPGASDDAVSCSVMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASL 270

  Fly   224 CKALINLDSAGSGGREILFQSGPNHPWLMN-YYRNVPHPFANTLAEELFQAGYIPSDTDFRIFRD 287
            .:|.|||::||.||:|::||:||.:|||:. |.....||||:.:|:|:||:|.|||||||||:||
Human   271 IRAFINLEAAGVGGKELVFQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRD 335

  Fly   288 YGGVPGLDMAYIFNGYVYHTKYNRINAFPRASFQHTGDNVLSLARALANAPELDDTAAHSEGHNI 352
            :|.:||:|:|:|.|||:|||||:..:.....|.|..|||:|::.:.||.:..|...:.:..|:.:
Human   336 FGNIPGIDLAFIENGYIYHTKYDTADRILTDSIQRAGDNILAVLKHLATSDMLAAASKYRHGNMV 400

  Fly   353 FYDFLGWFMIFYTETTSIIVNVVVTLLALLGVGISIYFMSLRSGCSWKGVLLRFSISIAIQFVSL 417
            |:|.||.|:|.|......|:|.:|.:..:|.:|........::|...|..|....|::...|.||
Human   401 FFDVLGLFVIAYPSRIGSIINYMVVMGVVLYLGKKFLQPKHKTGNYKKDFLCGLGITLISWFTSL 465

  Fly   418 ILAIGLALLVALFMDGVDRSMSWFTSSWTIFGLY----LAPIVFGLSILPALYLEKTKRDPLG-L 477
            :    ..|::|:|:..:.:|:||:...:....||    :|.|:...::....|........|| :
Human   466 V----TVLIIAVFISLIGQSLSWYNHFYVSVCLYGTATVAKIILIHTLAKRFYYMNASAQYLGEV 526

  Fly   478 GFRIQLFMHSHCICLIVIMLTLTGLSIRSAYLIMLCILFDIVA-LIVNLVTKWHRKAYLFAIAVT 541
            .|.|.||:|    |..::.||..||.  ||::..:.:.|.::. |.|:...|.|.....|.....
Human   527 FFDISLFVH----CCFLVTLTYQGLC--SAFISAVWVAFPLLTKLCVHKDFKQHGAQGKFIAFYL 585

  Fly   542 VCQILPLVFFTYLCTVALVTLMPMQGRSGSSTNPDMVIAALVWLFSLMFAGFIAPLIMFFRKTRT 606
            :...:|.::..||.........|:.|||||...||:|:|:::...:::.:.:....|...:.|:.
Human   586 LGMFIPYLYALYLIWAVFEMFTPILGRSGSEIPPDVVLASILAGCTMILSSYFINFIYLAKSTKK 650

  Fly   607 IVLCFLGITILFIIIAVTNAGFPYKEKTS---PQRYSLIHAHRRLHNADGSTRIDESGLYIYPQD 668
            .:|....:..:..::..:...|||....:   |:|..|.|..|..|:.:|:....:||::|...|
Human   651 TMLTLTLVCAITFLLVCSGTFFPYSSNPANPKPKRVFLQHMTRTFHDLEGNAVKRDSGIWINGFD 715

  Fly   669 RRFGIA--KDNIAAIGEAHQVSDFCDEEM-FCGMPLY-------NHRWNKARQYSMWIETSE-SP 722
            .. ||:  ..:|..|.::  :...|:|.. .||.|.|       ...|        ::...| ||
Human   716 YT-GISHITPHIPEINDS--IRAHCEENAPLCGFPWYLPVHFLIRKNW--------YLPAPEVSP 769

  Fly   723 EIPTEYPMLVLQDSSELETSAQRRFNFTLAGPSHMGIFINVKNDARILNWSF-NDTLIREQAEPP 786
            ..|..:.::    |.|.......:..|...|||||..::.....:.:..||. |.|.:..:. ..
Human   770 RNPPHFRLI----SKEQTPWDSIKLTFEATGPSHMSFYVRAHKGSTLSQWSLGNGTPVTSKG-GD 829

  Fly   787 YMVYFSYGLDDSPLEFTIDVELNDYLQKTTSTFDTPTLEIGIGGHWVTQDITAIEKLSSYINRFP 851
            |.|::|:||..|..:|.|:|::::...:...|       :.|..|:::.:.....:|.:...:||
Human   830 YFVFYSHGLQASAWQFWIEVQVSEEHPEGMVT-------VAIAAHYLSGEDKRSPQLDALKEKFP 887

  Fly   852 SYAYIQGWVGTYETWYF 868
            .:.:...||.||:.:.|
Human   888 DWTFPSAWVCTYDLFVF 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10062	NP_001261089.1	M28_Fxna_like	59..364	CDD:349872	141/308 (46%)
ERMP1	NP_079172.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..65
		M28_Fxna_like	104..412	CDD:349872	141/308 (46%)