Protein Alignment CG11961 and VPS70

DIOPT Version :9

• Sequence 1: NP_001246418.1
• Gene: CG11961 / 37221
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_012660.1
• Gene: VPS70 / 853590
• SGDID: S000003887
• Length: 811
• Species: Saccharomyces cerevisiae
• Alignment Length: 355
• Identity: 78/355 - (21%)
• Similarity: 132/355 - (37%)
• Gaps: 81/355 - (22%)

  Fly    77 RLPR----PLTIQDEETHPDQFIAERAEKNLRELVSLGPRVVGSRQNEMAALKMLSQKMQKIRSG 137
            |:||    |::.:|.     |.|.||.  |.|.. .:||   ||...:..:....|..:.|:.
Yeast   361 RVPRIPSVPMSARDV-----QPILERL--NGRGF-QIGP---GSNIKDFGSFTGPSSSIDKVH-- 412

  Fly   138 TANDIEVDVQVASGSYVHWSMVNMYQSIQNIVVKISPKNTNSTTYLLVNSHYDSVPAGPGAGDDG 202
            ..|::..:::..|.                  |::|.....:...:::.:|.||: |...|||..
Yeast   413 LHNELTYNIKEMSS------------------VEVSIPGIFTEGEIIIGAHRDSL-ASSSAGDAN 458

  Fly   203 SMVATMMEVLRVLAK----SDKPLKNPVVFLFNGAEENPLQAS------HAFITQHKWAKYCKAL 257
            |..|.::|:.|.::|    ..|||: |:..:....|.:.|..|      ||.|.:.:...|
Yeast   459 SGSAILLEIARGMSKLLKHGWKPLR-PIKLISWDGERSGLLGSTDYAEAHAAILRRRALVY---- 518

  Fly   258 INLDSCGNGGREILFQSGPNHPWLMKNYRRAIKHPYASTMGEE---LFQH---------NFIPSD 310
            :|||:..:|..   |....| |.|......|.|  .....|.|   ||.|         :.:...
Yeast   519 LNLDNAISGTN---FHCKAN-PLLQDVIYEAAK--LTEFNGHEDWSLFDHWKYTSNATISLLDGL 577

  Fly   311 TDFRIFRDHGSVPGLDMAYTYN---GFVYHTR--HDK---AEIFPRGSFQ-HTGDNLLALVRQIA 366
            :.:..|:.|..||.....:..|   |.|||:.  .|.   .|.|....:: |   |.:|:...:.
Yeast   578 SSYTSFQYHLGVPAAHFQFNANDTSGAVYHSNSVFDSPTWLEKFTNSDYKLH---NTMAMFVGLT 639

  Fly   367 NSPEIENSAKYAKGHTIYFDVMGWFLVFYT 396
            .....||.......|.....:..|::.:::
Yeast   640 TLMLSENELARFNTHVYLKKIYNWYIAWHS 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_001246418.1	M28_Fxna_like	91..395	CDD:193497	73/334 (22%)
VPS70	NP_012660.1	Zinc_peptidase_like	135..>187	CDD:417508
		PA_GCPII_like	187..413	CDD:239036	17/64 (27%)
		M28_PMSA_TfR_like	419..649	CDD:349871	58/262 (22%)
		TFR_dimer	<731..799	CDD:398094

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900