Protein Alignment: CG11961 and ERMP1

• Sequence 1: NP_001246418.1
• Gene: CG11961
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_079172.2
• Gene: ERMP1
• HGNCID: 23703
• Length: 904
• Species: Homo sapiens
• Alignment Length: 843
• Identity: 257/844 (30%)
• Similarity: 436/844 (52%)
• Gaps: 66/844 (8%)

  Fly    82 LTIQDEETHPDQFIAERAEKNLRELVSLGPRVVGSRQNEMAALKMLSQ--KMQKIRSGTANDIEV 144
            |.::....|..:|.|.:|...|..:.|:|||..||.:||:..:..|.:  |:.:::|.:.:.|.|
Human    95 LVLRGAAGHRGEFDALQARDYLEHITSIGPRTTGSPENEILTVHYLLEQIKLIEVQSNSLHKISV 159

  Fly   145 DVQVASGSY---VHWSMVNMYQSIQNIVVKISPKNTNSTTYLLVNSHYDSVPAGPGAGDDGSMVA 206
            |||..:||:   ......:.|.:|.|:|||:.|:: .:...:|.|.|:|||...|||.||....:
Human   160 DVQRPTGSFSIDFLGGFTSYYDNITNVVVKLEPRD-GAQHAVLANCHFDSVANSPGASDDAVSCS 223

  Fly   207 TMMEVLRVLAKSDKPLKNPVVFLFNGAEENPLQASHAFITQHKWAKYCKALINLDSCGNGGREIL 271
            .|:||||||:.|.:.|.:.|:|||||||||.|||||.|||||.||...:|.|||::.|.||:|::
Human   224 VMLEVLRVLSTSSEALHHAVIFLFNGAEENVLQASHGFITQHPWASLIRAFINLEAAGVGGKELV 288

  Fly   272 FQSGPNHPWLMKNYRRAIKHPYASTMGEELFQHNFIPSDTDFRIFRDHGSVPGLDMAYTYNGFVY 336
            ||:||.:|||::.|..|.|||:||.:.:|:||...|||||||||:||.|::||:|:|:..||::|
Human   289 FQTGPENPWLVQAYVSAAKHPFASVVAQEVFQSGIIPSDTDFRIYRDFGNIPGIDLAFIENGYIY 353

  Fly   337 HTRHDKAEIFPRGSFQHTGDNLLALVRQIANSPEIENSAKYAKGHTIYFDVMGWFLVFYTETEGV 401
            ||::|.|:.....|.|..|||:||:::.:|.|..:..::||..|:.::|||:|.|::.|....|.
Human   354 HTKYDTADRILTDSIQRAGDNILAVLKHLATSDMLAAASKYRHGNMVFFDVLGLFVIAYPSRIGS 418

  Fly   402 ILNVIVSLVSIGICGYAFKLMSVNSGIKLEKILKKVGHTLLVQILSVVVGAILPVLLGLFMDAVH 466
            |:|.:|.:..:...|..|......:|...:..|..:|.||:....|:|...|:.|    |:..:.
Human   419 IINYMVVMGVVLYLGKKFLQPKHKTGNYKKDFLCGLGITLISWFTSLVTVLIIAV----FISLIG 479

  Fly   467 LPLSWFSNSWLILGLYFTTFFFGLAIVPAL--YFHWTKRDKLPIGQ---RVQLLLHCHCLLLSVL 526
            ..|||:::.::.:.||.|.....:.::..|  .|::.......:|:   .:.|.:|| |.|:::
Human   480 QSLSWYNHFYVSVCLYGTATVAKIILIHTLAKRFYYMNASAQYLGEVFFDISLFVHC-CFLVTL- 542

  Fly   527 TLIFTICGIRSVFVLMLSCLFYTVGLIINIAT----KLHTKDVAWVIPHIVCTVPPFVFFAYFSH 587
                |..|:.|.|:   |.::....|:..:..    |.|.....::..:::....|:::..|...
Human   543 ----TYQGLCSAFI---SAVWVAFPLLTKLCVHKDFKQHGAQGKFIAFYLLGMFIPYLYALYLIW 600

  Fly   588 GFFTTFIPMFGRFGENLNPDLAVAVFSVAVGFLCCGFIIPVLQLFNKSKTIICGLMGITLLC--- 649
            ..|..|.|:.||.|..:.||:.:|........:...:.|..:.|...:|..   ::.:||:|
Human   601 AVFEMFTPILGRSGSEIPPDVVLASILAGCTMILSSYFINFIYLAKSTKKT---MLTLTLVCAIT 662

  Fly   650 FIIAMTPIGFPY-----RPETNVQRFAVLHTKRTFHDAQNKVRRQESGYFIMPQDRRTYTVKNAV 709
            |::..:...|||     .|:.  :|..:.|..|||||.:....:::||.:|...|   ||   .:
Human   663 FLLVCSGTFFPYSSNPANPKP--KRVFLQHMTRTFHDLEGNAVKRDSGIWINGFD---YT---GI 719

  Fly   710 INMT-----LAQRIGSDCDKEIN-CGLPLYNQRWHKTRKNSLW-IPASEPVLGENVPTVLLLSKN 767
            .::|     :...|.:.|::... ||.|.|.......|||  | :||.| |...|.|...|:||.
Human   720 SHITPHIPEINDSIRAHCEENAPLCGFPWYLPVHFLIRKN--WYLPAPE-VSPRNPPHFRLISKE 781

  Fly   768 TVSPTKIRYEMQLSGPNHMALFIQPLNGAKMMDWSFHQAPLRLSFEPPYFIYFSWGVNGDPLKFW 832
            ......|:...:.:||:||:.:::...|:.:..||........|....||:::|.|:.....:||
Human   782 QTPWDSIKLTFEATGPSHMSFYVRAHKGSTLSQWSLGNGTPVTSKGGDYFVFYSHGLQASAWQFW 846

  Fly   833 LEL----EKPNGNWNSSTLELGLGGHWNHHKELITPDFKKFLDSFPHYVDATPWPASFESRIF 891
            :|:    |.|.|     .:.:.:..|:...::..:|......:.||.:...:.|..:::..:|
Human   847 IEVQVSEEHPEG-----MVTVAIAAHYLSGEDKRSPQLDALKEKFPDWTFPSAWVCTYDLFVF 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_001246418.1	M28_Fxna_like	91..395	CDD:193497	136/309 (44%)
ERMP1	NP_079172.2	M28_Fxna_like	104..412	CDD:193497	136/309 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C368783164
eggNOG	1	0.900				E1_COG2234
Hieranoid	1	1.000
Homologene	1	1.000				H121891
Inparanoid	1	1.050	418	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D152011at33208
OrthoFinder	1	1.000				FOG0000590
OrthoInspector	1	1.000				T608307
orthoMCL	1	0.900				OOG5_128724
Panther	1	1.100			O	PTHR12147
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1738
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	13	12.790