Protein Alignment CG11961 and Tfr2

DIOPT Version :9

• Sequence 1: NP_001246418.1
• Gene: CG11961 / 37221
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: XP_030110515.1
• Gene: Tfr2 / 50765
• MGIID: 1354956
• Length: 840
• Species: Mus musculus
• Alignment Length: 628
• Identity: 129/628 - (20%)
• Similarity: 197/628 - (31%)
• Gaps: 257/628 - (40%)

  Fly    48 GNKIKWFWAPA---------------FFGFWLLLYVTISIPACHRLPRPLTIQDEETHPD----- 92
            |..|...||.|               |.|.:||.||... .:|......:.:.||:.:|:
Mouse   107 GRSIPIPWAAAGRKAAPYLVLITLLIFTGAFLLGYVAFR-GSCQACGDSVLVVDEDVNPEDSGRT 170

  Fly    93 ------------QFIAE-RAEKNLRELVSLGPRVVGSRQNEMAAL------KMLSQKMQKIRSGT 138
                        :|:.| |.|..:| |.||..||.||.:  ||.|      |:..||:..:.:.|
Mouse   171 TLYWSDLQAMFLRFLGEGRMEDTIR-LTSLRERVAGSAR--MATLVQDILDKLSRQKLDHVWTDT 232

  Fly   139 ANDIEVDVQV---ASGSYVHWSMVNMYQSIQNIVVKISPK------NTNSTTYLLVNSHYDSVPA 194
            .   .|.:|.   |..:.:||  |:...|:|..:....|:      .|.:.|..||.:||
Mouse   233 H---YVGLQFPDPAHANTLHW--VDADGSVQEQLPLEDPEVYCPYSATGNATGKLVYAHY----- 287

  Fly   195 GPGAGDD------------GSMVATMMEVL----RVLAKSDKPLKNPVVFL----FNGAEENPLQ 239
              |..:|            ||::...:.:.    :|....|...:..:::.    |:.....|..
Mouse   288 --GRSEDLQDLKAKGVELAGSLLLVRVGITSFAQKVAVAQDFGAQGVLIYPDPSDFSQDPHKPGL 350

  Fly   240 ASHAFITQHKWAKYCKALINLDSCGNG-------------------------------GREILFQ 273
            :||..:..|         ::|   |.|                               ..:|..|
Mouse   351 SSHQAVYGH---------VHL---GTGDPYTPGFPSFNQTQFPPVESSGLPSIPAQPISADIADQ 403

  Fly   274 -----SGPNHPWLMKNYRRAIKHPYASTMGEE--LFQHNFIPSDTDFRIFR--------DHGSV- 322
                 :||..|...|.:...  .||....|.:  |..:|...|.....||.        ||..|
Mouse   404 LLRKLTGPVAPQEWKGHLSG--SPYRLGPGPDLRLVVNNHRVSTPISNIFACIEGFAEPDHYVVI 466

  Fly   323 --------PG-----------LDMAYTY-----NGFVYHTRHDKAEIF---PRGSFQHTGDNLLA 360
                    ||           |::..|:     |||    |..::.:|   ..|.|...|
Mouse   467 GAQRDAWGPGAAKSAVGTAILLELVRTFSSMVSNGF----RPRRSLLFISWDGGDFGSVG----- 522

  Fly   361 LVRQIANSPEIENSAKYAKGHTIYFDVMGWFLVFYTETEGVILN----------VIVSLVSIGIC 415
                         :.::.:|   |..|:....|.|...:..:|.          ::|||:
Mouse   523 -------------ATEWLEG---YLSVLHLKAVVYVSLDNSVLGDGKFHAKTSPLLVSLI----- 566

  Fly   416 GYAFKLMSVNSGIKLEKILKKV------GHTLLVQILSVVVGAILPVLLGLFMDAVHLPLSWFSN 474
                           |.|||:|      |.||..|:..........|:..|.||:     |.:|
Mouse   567 ---------------ENILKQVDSPNHSGQTLYEQVALTHPSWDAEVIQPLPMDS-----SAYS- 610

  Fly   475 SWLILGLYFTTFFFGLAIVPALYFHWTKRDKLPIGQRVQLLLH 517
                    ||.|    |.|||:.|.:.:.|      ||...||
Mouse   611 --------FTAF----AGVPAVEFSFMEDD------RVYPFLH 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_001246418.1	M28_Fxna_like	91..395	CDD:193497	82/430 (19%)
Tfr2	XP_030110515.1	PA_TfR	248..438	CDD:239043	36/212 (17%)
		M28_TfR	446..679	CDD:349946	54/259 (21%)
		TFR_dimer	706..830	CDD:367885

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900