Protein Alignment CG11961 and erm2

DIOPT Version :10

• Sequence 1: NP_725876.1
• Gene: CG11961 / 37221
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_588494.1
• Gene: erm2 / 2539157
• PomBaseID: SPCC1919.12C
• Length: 843
• Species: Schizosaccharomyces pombe
• Alignment Length: 709
• Identity: 170/709 - (23%)
• Similarity: 285/709 - (40%)
• Gaps: 158/709 - (22%)

  Fly    41 CERAFVQGNKIKWFWAPAFFGFWLLLYV-TISIPACHRLPRPLTIQDEETHPDQFIAERAEKNLR 104
            |.:||...      ...:.|||.:||.: .:......::|.|..::|.|       .:||..:|.
pombe    13 CAKAFQSS------LTCSIFGFTVLLILYLLDWKRIAQVPGPNLLKDLE-------FQRAWNDLE 64

  Fly   105 ELVSLGPRVVGSRQNE---------MAALKMLSQKMQKIRSGTANDIEVDVQVASGSYVHWSMVN 160
            .:.|| |....|:|||         |..|:..:|....:...|..:|..:           |..|
pombe    65 YISSL-PHPYNSKQNEHVRSYILKSMRELEATNQSYITVIDDTLTNITFE-----------STDN 117

  Fly   161 ---MYQSIQNIVVKISPKNTNSTTYLLVNSHYDSVPAGPGAGDDGSMVATMMEVLRVLAKSDKPL 222
               .|....||:||...|:.:... :|:::|:|||..|.||.|||..|||:|.:.|..|| ::|.
pombe   118 DTLTYFEGDNILVKFEGKSKDLFP-ILLSAHFDSVSTGYGATDDGMGVATVMAIARYYAK-NQPN 180

  Fly   223 KNPVVFLFNGAEENPLQASHAFITQHKWAKYCKALINLDSCGNGGREILFQSGPNHPWLMKNYRR 287
            ::.::.: |.|||:.|..:.|| ..||.:|...|.:||:..|:||:.:||:|...|  :...|.:
pombe   181 RDLIINI-NNAEEDYLFGAKAF-ASHKLSKNVTAFVNLEGAGSGGKAMLFRSSNGH--VSSAYFK 241

  Fly   288 AIKHPYASTMGEELFQHNFIPSDTDFRIF-RDHGSVPGLDMAYTYNGFVYHTRHDKAEIFPRGSF 351
            ...:|.||.:|.:.|:...|.|.||:.:: :.|....|||:|:..|..:||||.|........|.
pombe   242 GNHYPLASILGNDFFKRGVIRSQTDYIVYEKMHNHTAGLDIAFYENRDIYHTRKDDINHLMPSSL 306

  Fly   352 QH---TGDNLLALVRQIANSPEIENSAKYAKGHTIYFDVMGWF----LVFYTETEGVILNVIVSL 409
            :|   |..|   .|:.:.|..: .:..|:.|  .::|...|.:    |..|.     :||:|.::
pombe   307 RHMMYTASN---AVKNLLNDSK-SDLTKFRK--PMFFLAFGKYWQLNLPIYQ-----VLNIIFAV 360

  Fly   410 VSIGICGYAFKLMSVNSGIKLEKILKKVGHTL--LVQILSVVVGAILPVLLGLFMDAVHLPLSWF 472
                ||.....|..:......|: |||..:|:  :|..:.|.:...|.|||          |:|.
pombe   361 ----ICPIVLLLTLIRFPSLYEQ-LKKPRYTVCFVVSCIFVSIFDTLTVLL----------LTWI 410

  Fly   473 ------SNSWLILGLYFTTFFFGLAI---VPALYFHWTKRDKLPI-------GQRVQLLLHCHCL 521
                  |::.|||.|::.|....||.   ..|.:...:..|...|       .|.:..|:....:
pombe   411 NPYVINSHTGLILALFYLTNLIALAFSFRAAATHSKLSSEDLSSIEIVFIWYAQILWYLVFIVSV 475

  Fly   522 LLSVLTLIFTICGIRSVFVLMLSCLFYT-----------------------VGLIIN-------- 555
            :||:...:.:...:...::...:|...|                       :|..||
pombe   476 ILSIYFQLGSTYWVTLSYLCTFTCCIMTIIRINYFVDNVVTTQTTHEEDALIGSSINTSSHQHYG 540

  Fly   556 --------------IATKLHTK--DVAWVIPHIVCTVPPFVFFAYFSHGFFTTFIPMFGR----- 599
                          ::.:.|.|  |..|.:.:.:..||..||..|  .....|.:|...:
pombe   541 STLNSTPHRRNSIALSNRAHVKLIDNIWTVIYFIFNVPFPVFLCY--DILVETILPAGSQTLTDS 603

  Fly   600 -FGENLNPDLAVAVFSVAVGFLCCG-FIIPVLQLFNKSKTIICGLMGITLLCFIIAMTP 656
             |...|   ..:.:|.|.:..:..| ||...|   :|....:..::.|||....:::.|
pombe   604 VFSSKL---YKLVIFVVFLSLVNSGPFIFRAL---SKKSLAVLTMLWITLFVQALSVNP 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_725876.1	M28_Fxna_like	91..395	CDD:349872	94/323 (29%)
		MFS	<539..>658	CDD:475125	29/172 (17%)
erm2	NP_588494.1	M28_Fxna_like	57..344	CDD:349872	93/310 (30%)