Protein Alignment CG11961 and erm1

DIOPT Version :10

• Sequence 1: NP_725876.1
• Gene: CG11961 / 37221
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_001342785.1
• Gene: erm1 / 2539040
• PomBaseID: SPCC1259.02C
• Length: 822
• Species: Schizosaccharomyces pombe
• Alignment Length: 836
• Identity: 214/836 - (25%)
• Similarity: 353/836 - (42%)
• Gaps: 182/836 - (21%)

  Fly    76 HRLPRPLTIQDEETHPDQFIAERAEKNLRELV-SLGPRVVGSRQNEMAALKMLSQKM---QKIRS 136
            :.|..||....:.....||....|.|::..|. .:|.|::|:.:.|.|...::::.:   ::::.
pombe    37 NHLDEPLVDPYDANGNPQFSEANALKHVIHLSDDIGYRILGTIEQERAREYIMNEVLALQKQLQD 101

  Fly   137 GTANDI-EVDVQVASG------SYVHWSMVNMYQSIQNIVVKISPKNTNST-----TYLLVNSHY 189
            |...|| :::|.:.||      .:::..::..||:::||||::|    |.|     ..:|:|:|.
pombe   102 GPNADIHQMEVSLESGDGAHRFDFMNKYVIKKYQNLKNIVVRLS----NGTEACKEEAVLINAHV 162

  Fly   190 DSVPAGPGAGDDGSMVATMMEVLRVLAKSDKPLKNPVVFLFNGAEENPLQASHAFITQHKWAKYC 254
            ||....|||.||...||.::|.:|:......||.:.:|||||.|||:...|||.||||.......
pombe   163 DSTLPSPGATDDALAVAILLEAIRIFISRPVPLTHSIVFLFNDAEESLQDASHMFITQSPLRDTI 227

  Fly   255 KALINLDSCGNGGREILFQSGPNHPWLMKNYRRAIKHPYASTMGEELFQHNFIPSDTDFRIFRDH 319
            |.::||::||..|.|||||:..|.  ::|.|.. :.||:.:.:.:::|:...|.||||||.|..:
pombe   228 KCVVNLEACGTTGSEILFQATSNE--MIKAYSH-VPHPFGTVLADDVFRTGLILSDTDFRQFVQY 289

  Fly   320 GSVPGLDMAYTYNGFVYHTRHDKAEIFPRGSFQHTGDNLLALVRQIANSPEIENSAKYAKGHTIY 384
            |::.|||||...|.::|||:.|.|.....|:.|:.|:|:||::..:. |||.:.:...:.| |:|
pombe   290 GNLTGLDMAVVKNSYLYHTKKDLAPYISPGTPQNFGENILAILTYLV-SPEADLNNMKSSG-TVY 352

  Fly   385 FDVMGWFLVFYTETEGVILNVIVSLVSIGICGYAFKLMSVNSGIKLEKILKKVGHTLLVQILSV- 448
            |.|.......|::....|||.:|     |..|....|........:         .|:.|::|:
pombe   353 FSVFNSLFFMYSKLTSKILNTLV-----GGLGILLTLRGSEGSFTV---------ALIAQVISIA 403

  Fly   449 ---VVGAILPVLLGLFMDAVHLPLSWFSNSWLILGLYFTTFFFGLAIVPALYFHWTKRDKLPIGQ 510
               |:..|...:||..:|.   .:|||.|.:..|.:|....|..|....:|:    ||.:
pombe   404 GIFVIPNIWAYILGNVLDC---GMSWFRNEYWPLFIYLPAIFASLFFTESLF----KRSE----- 456

  Fly   511 RVQLLLHCHCLLLSVLTLI-------FTICGIRSVFVLMLSCLFYTVGLIINIATKLHTKDVAWV 568
              .|.|.....:.|:||.|       |||.....||.|.|:             .|:..|.
pombe   457 --HLALRATIFIFSLLTFIPLPSAYLFTIIDFFMVFALFLN-------------DKILAKP---- 502

  Fly   569 IPHIVCTVPPFVFF----AYFSHGF------FTTFIPMFGRFGENLNPDLAVAVFSVAVGFLCCG 623
                 .||.|..:|    ...:.||      ...|:|:.||.|.:...|..||...|      ||
pombe   503 -----GTVHPLTYFIGSIGAMTVGFESAINLLEIFVPLTGRIGTDKVADNVVATVCV------CG 556

  Fly   624 FII------PVLQLFNKSKTIICGLMGITLLCFIIAMTPIGFPYRPETNVQRFAVLHTKRTFHDA 682
            |.|      |.:|.|   ::..|..:|:....|::..:..              :|..:.|::|:
pombe   557 FNIYFPLMSPWIQRF---RSRCCFRLGLLFSIFVVGFSSF--------------ILAKQDTYYDS 604

  Fly   683 QNKVRRQESGYFIMPQDRRTYTVKNAVINMTLA------QRIGSDC------DKEINCGLPLYNQ 735
            .:..|       |..|.....|.....:::..|      .::.||.      :..:...:..:|.
pombe   605 LHPRR-------IFVQRMENITSNEVSLHIASADSAPGFDKLSSDLSSLLTDEPVVKTEMDDWNS 662

  Fly   736 RWHKTRK-----NSLWIPASEPVLGENVPTVLLLSK----NTVSPTKIRYEMQLSGPNHMALFIQ 791
            .|.....     .|..||.::.|....:|::...:|    |.|:.| :..|       |..|...
pombe   663 DWDTVYPFSQFLGSYRIPLNDTVDVTTLPSIKFSNKVVKDNVVNVT-VTVE-------HPGLIWT 719

  Fly   792 PLN-GAKMMDWSFHQAPLRL----------------SFEPPYF---IYFSW-GVNG 826
            .:: .|.::.||..:.|..:                ||...|.   |||.: ||:|
pombe   720 VVSFDADVLSWSLPEVPSTVRRHHVREVSAYGLDSYSFNMSYLEAPIYFDFVGVDG 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_725876.1	M28_Fxna_like	91..395	CDD:349872	107/319 (34%)
		MFS	<539..>658	CDD:475125	30/134 (22%)
erm1	NP_001342785.1	M28_Fxna_like	52..363	CDD:349872	107/319 (34%)