Protein Alignment CG11961 and C44B7.11

DIOPT Version :10

• Sequence 1: NP_725876.1
• Gene: CG11961 / 37221
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: NP_495410.4
• Gene: C44B7.11 / 183431
• WormBaseID: WBGene00016631
• Length: 895
• Species: Caenorhabditis elegans
• Alignment Length: 895
• Identity: 239/895 - (26%)
• Similarity: 404/895 - (45%)
• Gaps: 124/895 - (13%)

  Fly    59 FFG-FWLLLYV-TISIPACHRLPRPLTIQDEETHPDQFIAERAEKNLRELVSLGPRVVGSRQNEM 121
            |.| |:|:|.: |..:..|  ||.|.....|||   ||..:||.|.|:||...|.:..||...|.
 Worm    45 FIGLFFLVLIIGTTFLHKC--LPEPKDPNQEET---QFSEKRAVKVLQELSDYGWKPAGSYNCEE 104

  Fly   122 AALKMLSQKMQKIRSGTAN----DIEVDVQVASGSY---VH--WSMVNMYQSIQNIVVKISPKNT 177
            .....:.:::..|||...|    ..::|.|..||.:   .|  ..|...|:::.|::.::.....
 Worm   105 LTRNRILKELNDIRSQNQNVENLRFDIDTQYVSGCFDIPAHDTEGMNICYRNVSNVMARLGKGEK 169

  Fly   178 NSTTYLLVNSHYDSVPAGPGAGDDGSMVATMMEVLRVLAKSDKPLKNPVVFLFNGAEENPLQASH 242
            .....:|:|.||||.|......||.|..|.|:|::|:.:|:...|.:.|:||||||||:.|.|:|
 Worm   170 KDKISVLLNCHYDSWPTSNAGSDDLSSCALMLELIRLYSKNPHLLNHDVIFLFNGAEESSLLAAH 234

  Fly   243 AFITQHKWAKYCKALINLDSCGNGGREILFQSGPNHPWLMKNYRRAIKHPYASTMGEELFQHNFI 307
            .|||||.|....:|.|||::.|:||||:|||:||.:.||:.:|..|..||:.|.:|:|:||....
 Worm   235 GFITQHSWRHEIRAFINLEASGSGGRELLFQAGPANQWLLNSYLEAAIHPHCSVIGQEVFQSGVY 299

  Fly   308 PSDTDFRIFRDHGSVPGLDMAYTYNGFVYHTRHDKAEIFPRGSFQHTGDNLLALVRQIANSPEIE 372
            |.|||||||||||.|||||:|:..||:.:||..|.||...:||.|..|:|:.:.:..:..||.:|
 Worm   300 PGDTDFRIFRDHGRVPGLDLAFVQNGYWWHTEFDTAERITKGSLQRAGENVYSTLNHLLKSPYLE 364

  Fly   373 NSAKYAKGHTIYFDVMGWFLVFYTETEGVILNVIVSLVSIGICGYAFKLMSVNSGIKLEKILKKV 437
            ..|:||...|::||.:|.|::.|..:...::|::.....|.:..:.|...:..:.:.|.
 Worm   365 KPAEYADRKTVFFDFLGLFVIIYPLSIAHLVNMLTICTVIALMSHRFYSKTFITFLALR------ 423

  Fly   438 GHTLLVQILSVVVGAILPVLLGLFMDAVHLPLSWFSNSWLILGLY-FTTFFFGLAIVPALYFHWT 501
            .:.|.:..:::|:.|:  ..:.||   .:..|.|::..||.|..| ..:.:.|:::...|.....
 Worm   424 DYVLTILTIALVLKAM--TFMSLF---TYGALRWYTRHWLALVAYGLPSVWAGISVQGLLTARLA 483

  Fly   502 KRDKLPIGQRVQLLLHCHCLLLSVLTLIFTICGIRSVFVLMLSCLFYTVGLIINIATKLHTKDVA 566
            .:.:...|..::|:   |..|:|.:.|.||...|.|.|:..|        |::.....:.|...|
 Worm   484 PKAREEYGSTLELI---HLTLISGILLAFTYYDIASGFLFAL--------LLVPAIKSIITYFGA 537

  Fly   567 W-------VIPHIVCTVPPFVFFAYFSHGFFTTFIPMFGRFGENLNPDLAVAVFSVAVGFLCCGF 624
            |       .|..::.:.|......|.:....:.|||:.||  .:.||:.||:.|   |.|.....
 Worm   538 WPTCPTFNTILTLILSFPGCAMAIYTTEMLLSIFIPIMGR--SSYNPEPAVSFF---VAFSAGCI 597

  Fly   625 IIPVLQLFNKSKT-----------IICGLMGITLLCFIIAMTPIGF---PYRPET---NVQRFAV 672
            ::.:..|..||:.           :|..::|:.|:...|......|   |||.:.   ..:|...
 Worm   598 VLSLGGLVAKSRNSRSSNEAGLLELIYNILGVLLVTLTILYVFSSFWPSPYRFDNVYPTAKRTQF 662

  Fly   673 LHTKRTFHDAQNKVRRQESGYFIMPQDRR-----TYTVKNAVINMTLAQRIGSDCDKEIN--CGL 730
            .|..:..:|...::...::.::.:..|.|     .:..|:       .:..|..|..|.|  |..
 Worm   663 FHVNQMLYDRNGQISVNDTRFYAISHDYRGAEDIPFVKKD-------PEYTGLQCHYENNPWCET 720

  Fly   731 PL-------YNQRWHKTRKNSLWIPASEPVLGENVPTVLLLSKNTVSPTK-----IRYEMQLSGP 783
            |.       .|:|..:.|.....:....||      .:|.:||.....:|     |.|...:.|.
 Worm   721 PFLFPTKGRLNERNIRVRSVDERLKFKHPV------KILGISKRHGVDSKDGKGNIEYSFSVIGT 779

  Fly   784 NHMALFIQPLNGAKMMDWSFHQ--APLRLSFEPPYFIYFSWGVNGDPLKFWLEL------EKPNG 840
            ..::::|.|.....:.:.|..|  .|     :...|:|::.....:..::..::      :.|:
 Worm   780 GQISVYIIPDTTWLITNTSVTQPKTP-----QENMFLYYTCSTPNNICEWMFKVTIKKTTQTPS- 838

  Fly   841 NWNSSTLELGLGGHWNHHKELITPDFKKFLDSF-------PHY-VDATPW 882
              :...|.:|:..|:.|..|:.:...|..:...       |.: |.|:.|
 Worm   839 --DDKPLLIGISSHYLHGPEMQSESIKNMIAKIQENRVNSPEWTVTASAW 886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_725876.1	M28_Fxna_like	91..395	CDD:349872	124/312 (40%)
		MFS	<539..>658	CDD:475125	28/136 (21%)
C44B7.11	NP_495410.4	M28_Fxna_like	75..387	CDD:349872	125/314 (40%)
		COG5373	<444..>646	CDD:444140	49/220 (22%)