DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11961 and gcp-2.2

DIOPT Version :9

Sequence 1:	NP_001246418.1	Gene:	CG11961 / 37221	FlyBaseID:	FBgn0034436	Length:	891	Species:	Drosophila melanogaster
Sequence 2:	NP_509928.3	Gene:	gcp-2.2 / 183230	WormBaseID:	WBGene00007954	Length:	779	Species:	Caenorhabditis elegans

Alignment Length:	389	Identity:	86/389 - (22%)
Similarity:	143/389 - (36%)	Gaps:	102/389 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 NMYQSIQNIVVKISPKNTNSTTYLLVNSHYDSVPAGPGAGDDGSMVATMMEVLRVLAKSDK---- 220
            |..:.||||:..|. .:.....::||::|||:...  ||.|..|..:|::||.|.|.:...
Worm   368 NEERKIQNIMGYIK-GSQEPDKFVLVSNHYDAWTY--GAVDPNSGTSTLLEVSRALKQYQNQTGW 429

  Fly   221 -PLKNPVVFLFNGAEENPLQASHAFITQHK--WAKYCKALINLDSCGNGGREILFQSGPNHPWLM 282
             |.:: ::|....|||..|..|..|..:::  ..:...|:||:|..| |.:.:|..|.|....::
Worm   430 IPARS-ILFAHWDAEEYGLIGSTEFAEEYRLQLMRRAVAVINMDLIG-GNQTLLGLSNPTVANVL 492

  Fly   283 KNYRRAIKHPYASTM--GEELFQHN---FIPSDTDFRIFRDHGSVPGLDMAYTYNGFVYHTRHDK 342
            ::....::.|..:.|  |.:....:   :.||..:                        .:.|..
Worm   493 RSAAANVEQPNPTEMEQGRKTLYDSWKYYAPSKNN------------------------RSTHPY 533

  Fly   343 AEIFPRGS-----FQHTGDNLLALVRQIANSPEIENSAKYAKGHTIYFDVMGWFLVFYTETEGVI 402
            ..|...||     |.:.|..::..:....::|     ..|...||||            ||..:|
Worm   534 QRIPAGGSDHLPFFDYLGIPIVFFITSSLDAP-----PTYPLYHTIY------------ETPYLI 581

  Fly   403 LNVIVSLVSIGICGYAFKLMSVNSGIKLEKILKKVGHTLLVQILSVVVGAILPVLLGLFMD---A 464
            .|::..       ||              |:.|.:....:..||......|||..|...||   .
Worm   582 ENIMDP-------GY--------------KVHKAIAGMFIECILKFTESKILPYDLNELMDDSIF 625

  Fly   465 VHLP-LSWFSNSWLILGLYFTTFF------FGLAIVPALYF-------HWTKRDKLPIGQRVQL 514
            .:|| |....|..|::|.. |.:.      |.|.....|..       :.:|.::||.|.||.:
Worm   626 EYLPKLEDRLNKTLMIGTK-TDYLLDAQKQFKLLQKTVLELSEIVQRRNVSKLEELPFGSRVDI 688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_001246418.1	M28_Fxna_like	91..395	CDD:193497	54/251 (22%)
gcp-2.2	NP_509928.3	Zinc_peptidase_like	75..>133	CDD:301362
		PA_GCPII_like	137..364	CDD:239036
		M28_PSMA_like	372..614	CDD:193568	65/308 (21%)
		TFR_dimer	652..773	CDD:282153	9/37 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2234
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900