Protein Alignment CG11961 and ermp1

DIOPT Version :10

• Sequence 1: NP_725876.1
• Gene: CG11961 / 37221
• FlyBaseID: FBgn0034436
• Length: 891
• Species: Drosophila melanogaster
• Sequence 2: XP_004910853.1
• Gene: ermp1 / 100145630
• XenbaseID: XB-GENE-984733
• Length: 876
• Species: Xenopus tropicalis
• Alignment Length: 871
• Identity: 262/871 - (30%)
• Similarity: 434/871 - (49%)
• Gaps: 89/871 - (10%)

  Fly    64 LLLYVTISIPACHRLPRPLTIQDEETHPDQFIAERAEKNLRELVSLGPRVVGSRQNEMAALKMLS 128
            |||||.......|...|.|....  .|...|.|..|.:.|:::.|:..|:|||.:||:.|:..|.
 Frog    52 LLLYVLGVRGLVHISLRQLVTPG--GHSTGFNASTAREYLQQITSIDSRIVGSPENEIIAVDYLL 114

  Fly   129 QKMQKI--RSGTANDIEVDVQVASGSY---VHWSMVNMYQSIQNIVVKISPKNTNSTTYLLVNSH 188
            .|::.|  :..:.:.|.||||..:|::   ......:.|.:|.||.||:.|: ..:...:|.|.|
 Frog   115 GKIKDIEEKVNSVHKITVDVQRPTGTFSIDFLGGFTSYYDNITNIAVKLEPE-FGAEHAVLANCH 178

  Fly   189 YDSVPAGPGAGDDGSMVATMMEVLRVLAKSDKPLKNPVVFLFNGAEENPLQASHAFITQHKWAKY 253
            :|||...|||.||....|.|:|:|..|:.|.|||::.::|||||||||.||.||.|||||.|||.
 Frog   179 FDSVANTPGASDDAVSCAVMLEILGSLSVSSKPLRHAIIFLFNGAEENILQGSHGFITQHPWAKM 243

  Fly   254 CKALINLDSCGNGGREILFQSGPNHPWLMKNYRRAIKHPYASTMGEELFQHNFIPSDTDFRIFRD 318
            .:|.|||::.|.||:|::||:||.:|||::.|..|..||:||.:.:|:||...|||||||||:||
 Frog   244 VRAFINLEAAGVGGKELVFQTGPENPWLVQAYALAAVHPFASVVAQEVFQSGIIPSDTDFRIYRD 308

  Fly   319 HGSVPGLDMAYTYNGFVYHTRHDKAEIFPRGSFQHTGDNLLALVRQIANSPEIENSAKYAKGHTI 383
            .|::||:|:|:..||::|||::|........|.|..|||:|.::..:|.|.::..|:|:..|:.:
 Frog   309 FGNIPGIDLAFIENGYIYHTKYDTWNRILTESIQRAGDNILGVLHYLATSSQLAESSKFRHGNMV 373

  Fly   384 YFDVMGWFLVFYTETEGVILNVIVSLVSIGICGYAFKLMSVNSGIKLEKILK-KVGHT------- 440
            :|||.|.|::.|....|.|:|.|.:.|::...|              :||:| |.|.|
 Frog   374 FFDVCGLFVLSYPARLGTIINYITAAVTLFYIG--------------KKIIKYKQGGTNYARDLV 424

  Fly   441 --LLVQILSVVVGAILPVLLGLFMDAVHLPLSWFSNSWLILGLYFTTFFFGLAIVPALY------ 497
              .|:.::|.|...:..:::.:.:......|.|:::      .|.:.|.:|.|.|..|.
 Frog   425 YGFLITLVSWVSALVTVLIIAVLVSLAGKALFWYTH------FYVSVFLYGSAAVAKLILVHSLA 483

  Fly   498 --FHWTKRDKLPIGQ---RVQLLLHCHCLLLSVLTLIFTICGIRSVFVLMLSCLFYTVGLIINIA 557
              |.:.......:|.   .:.|::.|..|:|      .|..|:.|.:       |:...:|..:.
 Frog   484 KTFFFAGASSQYLGDVFFDISLIIWCIPLVL------LTQSGLCSAY-------FFAAWIIFPLL 535

  Fly   558 TKLHTK-DV-------AWVIPHIVCTVPPFVFFAYFSHGFFTTFIPMFGRFGENLNPDLAVAVFS 614
            |||..: |:       .:.:.:::...||::...|.....|..|.|:.||.|..:.||:.:....
 Frog   536 TKLLLQPDIIHQGSPYKFTVIYLLGLFPPYLHTMYHVWAVFEMFTPILGRSGTEIPPDVVLGFLI 600

  Fly   615 VAVGFLCCGFIIPVLQLFNKSKTIICGLMGITLLCFIIAMTPIGFPYRPETN---VQRFAVLHTK 676
            :|...:...:.|..:.|...:|.||..|..:::|.|::..:.:.|||...|:   .:|..:.||.
 Frog   601 IACTIMLISYFISFIYLVKNTKNIIVPLAVLSVLTFLLVCSGMFFPYSSSTDSPKPKRIFLQHTT 665

  Fly   677 RTFHDAQNKVRRQESGYFIMPQDRRTYTVKNAVINMT-----LAQRIGSDCDKEINCGLPLYNQR 736
            ||||....:|.:::||.:|...|   ||   .:.::|     |...:.:.||....||.|.|...
 Frog   666 RTFHSLTGEVVKKDSGIWINGFD---YT---GISHVTPHFPELNDTVRAPCDDAPLCGFPWYFPV 724

  Fly   737 WHKTRKNSLW-IPASEPVLGENVPTVLLLSKNTVSPTKIRYEMQLSGPNHMALFIQPLNGAKMMD 800
            .:..|||  | :||....:.|:. ...|:|:..:|....|...:..||:||.::::|...:.:..
 Frog   725 HNLIRKN--WYLPAPPAPIYEHT-EFKLVSREEMSWGTTRLHFEAKGPSHMTVYVRPHADSVLSS 786

  Fly   801 WSFHQAPLRLSFEPPYFIYFSWGVNGDPLKFWLELEKPNGNWNSSTLELGLGGHWNHHKELITPD 865
            ||........|.|..|||::|.|:.....|||:|: |.:.:.:...:.:.:|.|:.......:|.
 Frog   787 WSLGDGIPIASGEKDYFIFYSHGLYAPAWKFWIEV-KNSADESKGIVTVAVGSHYFFGDSRNSPH 850

  Fly   866 FKKFLDSFPHYVDATPWPASFESRIF 891
            .|.....||.:...:.|..:::..::
 Frog   851 LKTVELKFPDWSFPSSWVCTYDLYVY 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11961	NP_725876.1	M28_Fxna_like	91..395	CDD:349872	131/308 (43%)
		MFS	<539..>658	CDD:475125	26/126 (21%)
ermp1	XP_004910853.1	M28_Fxna_like	78..385	CDD:349872	131/307 (43%)