Protein Alignment EndoB and sh3glb2b

DIOPT Version :10

• Sequence 1: NP_611410.1
• Gene: EndoB / 37218
• FlyBaseID: FBgn0034433
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: XP_021331719.1
• Gene: sh3glb2b / 394094
• ZFINID: ZDB-GENE-040426-833
• Length: 421
• Species: Danio rerio
• Alignment Length: 427
• Identity: 170/427 - (39%)
• Similarity: 243/427 - (56%)
• Gaps: 59/427 - (13%)

  Fly     7 NFNVKNLVKEAGSTISRVVQLTEEKLGTTERTEYDLHFQNLAERADVTKTWTEKIVRDTESVLIP 71
            :||||.|..:||...:|.||.||||||..|:||.|.|.:||..|||.||.|||||.|.||.:|.|
Zfish     2 DFNVKKLASDAGVFFTRAVQYTEEKLGQAEKTELDAHLENLIARADCTKNWTEKIFRQTEVLLQP 66

  Fly    72 NPQN----RVEDFIFEKIEKSKPKRLSNLEHLALDMIEAGGDFGQDLPYGQALIKVGQAEQKLGQ 132
            ||.:    |:|:|.:||::|..|.|::|.|.|...|.:|..|||...|||..||.||:.:::||.
Zfish    67 NPIDQTGARIEEFFYEKLDKKIPSRITNAELLGQYMQDAAKDFGPGSPYGSTLITVGEYQKRLGG 131

  Fly   133 CEHDFIATSGICFTQPLRKFLDGEMKTIGKERGILETKRLDLDACKNRVKKARSMLGQQSKDGIS 197
            .|.:|:.||.|.|..|||.||:|:.|||.:||.:||.:|||||.||.|:|||:.   .::|...:
Zfish   132 SEREFLQTSAINFLTPLRNFLEGDWKTISRERRLLENRRLDLDVCKARLKKAKL---AEAKAAAA 193

  Fly   198 PE-----------------------------------AVLEQAERDLRVAQAEFDRQAEITKLLL 227
            |:                                   ..:::||.:|||||.|||||||:|:|||
Zfish   194 PDFQETRPRNYVLSASASAWDREVDESCLADREKLWSEEVDKAEHELRVAQTEFDRQAEVTRLLL 258

  Fly   228 DGISTSQASHLRHLHAFIQTQVRYYKQCGDVMEQLQRELANLGGPTPYIPLDVNEASASKSNISS 292
            :|||::..:|||.||.|::.|..||.||...|:.||:||::..|.|......||   ||.|.:|:
Zfish   259 EGISSTHVNHLRCLHEFVEAQAAYYAQCHRHMQDLQKELSSANGDTFPNAFAVN---ASTSGVSA 320

  Fly   293 GAAARGPGNNHSANMAATGHKPNQPMHVSTDQM------------QRARVLCSYDAKDHTELNLS 345
            |.:....|.  ....::....||.|..:.::.:            ::|:||..|||.|.:||:|.
Zfish   321 GPSPLSTGT--QPGPSSPSRPPNPPNALESNTLKIEEVKPPATGTRKAKVLYDYDAADTSELSLL 383

  Fly   346 ANEVIFVTECSPVNEDYMYGKQGLLKGLVPRAFVEML 382
            |:|:|.|.....::.|::.|::|..||.||..::|:|
Zfish   384 ADELITVYTVPGMDPDWLIGERGNQKGKVPVTYLELL 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoB	NP_611410.1	BAR_Endophilin_B	26..266	CDD:153278	123/278 (44%)
		SH3_Endophilin_B	327..378	CDD:212736	21/50 (42%)
sh3glb2b	XP_021331719.1	BAR	21..297	CDD:472257	123/278 (44%)
		SH3_Endophilin_B2	365..419	CDD:212877	21/53 (40%)