Protein Alignment EndoB and mug137

DIOPT Version :10

• Sequence 1: NP_611410.1
• Gene: EndoB / 37218
• FlyBaseID: FBgn0034433
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_588493.1
• Gene: mug137 / 2539113
• PomBaseID: SPCC1919.11
• Length: 420
• Species: Schizosaccharomyces pombe
• Alignment Length: 355
• Identity: 70/355 - (19%)
• Similarity: 147/355 - (41%)
• Gaps: 43/355 - (12%)

  Fly    21 ISRVVQLTEEKLGTTERTEYDLHFQNLAERADVTKTWTEKIVRDTESVLIPNPQNRVEDFIFEKI 85
            :||....|.||....:|......|..|.:...:.:....|:.:.| ::.|        |.|.:|:
pombe     2 VSRFFSWTNEKPLGDQRAHLPDSFLELEQEIAIREEGLSKLFQAT-TIWI--------DSILKKV 57

  Fly    86 EKSKPKRLSNLEHLALDMIEAGGDFGQDLPYGQALIKVGQAEQKLGQCEHDFIATSGICFTQPLR 150
            :....::....|:|...||....:..||..||..|.::|:|..|:|:.:......:.:|:...|:
pombe    58 DGEDKEKCLACENLGKVMINHSKELPQDSSYGITLSQLGKANLKIGEHQTSLAYKARVCYLDFLK 122

  Fly   151 KFLDGEMKTIGKERGILETKRLDLDACKNRVKKARSMLGQQSKDGISPEAVLEQAERDLRVAQAE 215
            ::| .:.|.....|..||::|   .|.::.::|:   ..::.:|        .:.|.|:|:|..:
pombe   123 RYL-VQAKDFHSARKKLESRR---QAYESLLQKS---FKEKKED--------SRLEEDIRLALYK 172

  Fly   216 FDRQAEITKLLLDGISTSQASHLRHLHAFIQTQVRYYKQCGDVMEQLQRELANLGGPTPYIPLDV 280
            |:...|..|..:..:...:|...:.|...|..::.::|:...::..:.....:|   ||...:..
pombe   173 FEESTEQVKNRMIALKDVEADQYQQLTELIVYELNFFKESTGILNTIFNSQNSL---TPQKKIQS 234

  Fly   281 NEASASKSNISSGAAARGPGN-------NHSANMAATGHKP-NQPMHVSTDQMQRARVLCSYDAK 337
            :|.|.....::|      |.:       ..:.|.......| :.|...|..:....:.:.|:..:
pombe   235 SERSVENEFLAS------PMDPSLSKLFTKTTNTEKISPTPFSTPKRKSKKETVFVKAIYSFTGR 293

  Fly   338 DHTELNLSANEVIFVTECSPVNEDYMYGKQ 367
            :..||:|...:||.|:|  .:..|:..|::
pombe   294 NEKELDLHTGDVIQVSE--QLGPDWYMGEK 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoB	NP_611410.1	BAR_Endophilin_B	26..266	CDD:153278	47/239 (20%)
		SH3_Endophilin_B	327..378	CDD:212736	10/41 (24%)
mug137	NP_588493.1	BAR_MUG137_fungi	17..230	CDD:153277	47/239 (20%)
		SH3	280..341	CDD:214620	10/44 (23%)