Protein Alignment: wbl and Erp29

• Sequence 1: NP_001286609.1
• Gene: wbl
• FlyBaseID: FBgn0004003
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_080405.1
• Gene: Erp29
• MGIID: 1914647
• Length: 262
• Species: Mus musculus
• Alignment Length: 276
• Identity: 81/277 (29%)
• Similarity: 137/277 (49%)
• Gaps: 48/277 (17%)

  Fly     1 MMHILVTLLLV-------AIHSIPTTWAVTCTGCVDLDELSFEKTVERFPYSVVKFDIAYPYGEK 58
            ::.:|:.|||:       .:|:         .|.:.||.::|.|.:.:..:.:||||..||||||
Mouse    16 LLSVLLGLLLLFAPHGGSGLHT---------KGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEK 71

  Fly    59 HEAFTAFSKSAHKATKDLLIATVGVKDYGELENKALGDRYKVDDKNFPSIFLFKGNADEYVQLPS 123
            .:.|...:::: .::::||:|.||:.|||:..|..|.::||:|.:::|..:||:
Mouse    72 QDEFKRLAENS-ASSEELLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFR----------- 124

  Fly   124 HVDVTLDNLKAFVSA-----------NTPLYIGRDGCIKEFNEVLKNYANIPDAEQLKLIEKLQA 177
              |..|:|...:..|           ...:|:|..||:..::.:...:......|..:.|.| |.
Mouse   125 --DGDLENPVLYNGAVKVGAIQRWLKGQGVYLGMPGCLPAYDALAGEFIKASSIEARQAILK-QG 186

  Fly   178 KQEQLTDPEQQQN-ARAYLIYMRKIHEVGYDFLEEETKRLLRLKAGKVTEAKKEELLRKLNILEV 241
            :...|:..|.::. |..||..|.||.:.|.||...|..|:.:|...|::::|||||.:.||||..
Mouse   187 QDGLLSVKETEKKWASQYLKIMGKILDQGEDFPASEMARIGKLIENKMSDSKKEELQKSLNILTA 251

  Fly   242 FRVHKVTKTAPEKEEL 257
            ||     |...|||||
Mouse   252 FR-----KKEAEKEEL 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wbl	NP_001286609.1	ERp29_N	22..147	CDD:254509	38/136 (28%)
		ERp29	149..242	CDD:285048	29/94 (31%)
Erp29	NP_080405.1	Thioredoxin_like	35..157	CDD:294274	39/145 (27%)
		ERp29	159..252	CDD:285048	29/94 (31%)
		Prevents secretion from ER. {ECO:0000255|PROSITE-ProRule:PRU10138}	259..262		3/3 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C294563769
eggNOG	1	0.900				E1_28K2V
Hieranoid	1	1.000
Homologene	1	1.000				H4963
Inparanoid	1	1.050	116	1.000	Inparanoid score	I4769
Isobase	1	0.950		0	Normalized mean entropy	S7243
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0010916
OrthoInspector	1	1.000				T1082533
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			LDO	PTHR12211
Phylome	1	0.910		0.667	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R4822
TreeFam	1	0.960
	13	12.840