Protein Alignment botv and Extl1

DIOPT Version :10

• Sequence 1: NP_523790.1
• Gene: botv / 37198
• FlyBaseID: FBgn0027535
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: NP_001101455.1
• Gene: Extl1 / 313610
• RGDID: 1309572
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 837
• Identity: 209/837 - (24%)
• Similarity: 332/837 - (39%)
• Gaps: 262/837 - (31%)

  Fly   166 SVEQAQVAQREAVQRNTPDLALPRSLLPNTLPRKSNPITGGMAASCEMHNCFNHSRCSLTSGFPV 230
            |..|.:....|.||:               |||.|.      .:||....||:.|:|   .|..:
  Rat    54 SFSQPETNPEEDVQQ---------------LPRVSR------GSSCTWGACFDTSKC---RGKVL 94

  Fly   231 YLYDPDEHS-------VQRKGYDIDGFLKTTLKQTLGYNAHIVKDPKHACIYLVLVGEALLEQDL 288
            .::   .||       .||:..|           :|..:.:....|..||:.|.|..:
  Rat    95 KIF---VHSAAGPTTEAQRRILD-----------SLEGSRYYALSPAEACLLLFLPSQ------- 138

  Fly   289 LRNNRYAAQEAEHQQPSTPTLENDC-PVDMEKLYSLPYWGGDGRNHVLLNLARRDLTSHRTNPLY 352
               :|..|                | |:.       |.|.| ||||::|:|.....|
  Rat   139 ---DRRGA----------------CGPLP-------PNWNG-GRNHLVLSLYPAPCT-------- 168

  Fly   353 RQNTMRAIVVQSAFEREQFRPGYDLIVP------PILGPPGGDVW----QECAEMVPA---RRKY 404
              ...:|:|.:::...:.||||:|:.:|      |:.|...|.:.    |..|.:|..   |.::
  Rat   169 --RLGQAMVAEASPSLDIFRPGFDVALPYLPEAHPLKGGAPGSLQRHGPQPGATLVAVAEERGRW 231

  Fly   405 LLTYQGELRPKQSSLNPLDAFILEHLADMAKGATQDQFVLQFQCVPATEQ-QEGDSLPDWTLCGS 468
            .:|      ...:|..|.|           :...||         |..:| ..|:.||:.|.|
  Rat   232 RIT------TTHASACPWD-----------RNCEQD---------PGPQQTYPGEILPNVTFC-- 268

  Fly   469 DSSRRQLLKDSTFSLILPPLNGRVSSTLMLARIYEALRSGAVPVILGADELRLPYAETVDWRRTA 533
                           ::|   |..|:|   :...:||::|.:||:| :....||::|.:||.:.|
  Rat   269 ---------------LIP---GHRSAT---SCFLQALQAGCIPVLL-SPRWELPFSEVIDWTKAA 311

  Fly   534 LLLPKARITELHFLLRAVQDADLLLLRRQGRLIWERYLSSVQATVDTVIASLRDRL-GIPPRPVP 597
            ::..:....::...||.:..:.:|.||:|.:.:|..|.|||:..|.|.:..::||: |....|
  Rat   312 IVADERLPLQVLAALREMLPSRVLALRQQTQFLWTAYFSSVEKVVHTTLEIIQDRIWGASAHP-- 374

  Fly   598 SVIAQSVFNSTFIPLKSDPPVGLDTEPEESLGPIEPPYPSPAFRRNYTILRMQAKEAWNDWLDPF 662
                ..::||        ||..|...|..|                 |.|:        |:  ||
  Rat   375 ----SLMWNS--------PPGALLALPTFS-----------------TSLQ--------DF--PF 400

  Fly   663 YLYPQLPFDPALPSEAKFMGSHTGFRPIGKGLGGAGKEFGESLGGNYPREQFTIVMLTYEREQVL 727
            | :.||                                      |:.|...|:.|:.....|:..
  Rat   401 Y-HLQL--------------------------------------GSSPGSSFSAVIWVGVSEESP 426

  Fly   728 MDSLGRLYGLPYLHKVVVVWNSPKPPLDDLRWPDIGVPVAVLRAPRNSLNNRFLPFDVIETEAVL 792
            ...:..:.|..:..:::::|||.|||.|  |||...||:.|:...| .:::||..:..|.|..:|
  Rat   427 PKLIQEVAGSRHCAQILILWNSEKPPPD--RWPKTAVPLTVIEGHR-KVSDRFFLYSNISTNVIL 488

  Fly   793 SVDDDAHLRHDEILFGFRVWREHRDRVVGFPGRYHAWDLGNPNGQWHYNSNYSCELSMVLTGAAF 857
            |:|..:.|...|:.|.|.||:...:|:|||....|.||.....  |.|::..:.|.|||||.|||
  Rat   489 SLDAQSTLSTSEVDFAFVVWQSFPERMVGFVTWSHFWDEARQG--WGYSAEMANEFSMVLTTAAF 551

  Fly   858 VHKYYLYLYTYHLPQAIRDKVDEYMNCEDIAMNFLVSHITRKPPVKV------------TSRWTF 910
            .|:||..|:|:.||:|:|...||...|.||.|||||:.:|:.||:||            .|....
  Rat   552 YHRYYHTLFTHSLPKALRSIADETPTCVDILMNFLVATVTKLPPIKVPYSRQHQEAAPMASEGPR 616

  Fly   911 RCPGCPVSLSEDDTHFQERHKCINFFSRVFGYTPLLNTQYRADSILFKTRIPHDKQK 967
            ..|. |.:|.:|         |||..:...|:.||::::.|.|.:|||..:...::|
  Rat   617 PVPE-PQALDQD---------CINRLAAGLGHMPLVSSRVRLDPVLFKDPVSVQRKK 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
botv	NP_523790.1	CC_brat-like	106..>179	CDD:475168	3/12 (25%)
		Exostosin	224..551	CDD:397245	72/348 (21%)
		Glyco_transf_64	714..953	CDD:430488	85/250 (34%)
Extl1	NP_001101455.1	Exostosin	108..329	CDD:397245	69/325 (21%)
		Glyco_transf_64	413..649	CDD:430488	85/250 (34%)