Protein Alignment botv and rib-2

DIOPT Version :10

• Sequence 1: NP_523790.1
• Gene: botv / 37198
• FlyBaseID: FBgn0027535
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: NP_499368.1
• Gene: rib-2 / 176502
• WormBaseID: WBGene00004361
• Length: 814
• Species: Caenorhabditis elegans
• Alignment Length: 945
• Identity: 321/945 - (33%)
• Similarity: 475/945 - (50%)
• Gaps: 179/945 - (18%)

  Fly    59 VLLMLLFLVSCLAYRILS---------VEQDAPPLDLHRSSPLLDAYEDFSAMRAG-DLKMRIEE 113
            |...|:|:...:.|.|:.         :.|||    |.::...||   |:.|..:| .:...:.|
 Worm    18 VSAFLIFIFFVITYIIIYNVSFSEPSWITQDA----LKQNIENLD---DYDASCSGYSIGRILRE 75

  Fly   114 MVRIKSTVSVELRELESRRQKLQSDISQYNQKIEELKQELLREQTELERLKISVEQAQVAQREAV 178
            ..||.::|.:||.|       .|..|.:.....|||::.:.::|.||..|:..:|.||....|..
 Worm    76 QKRILASVRLELTE-------SQVKIEEIRTVQEELQRLIPQKQLELSALEGEIEAAQRQLEELR 133

  Fly   179 QRNTPDLALPRSLLPNTLPRK-SNPITGGMAASCEMHNCFNHSRCSLTSGFPVYLYDPDEHSVQR 242
            :.....:.||.|  |..:||: ..|   ...:..::.:..::||||::|..|||:      .:..
 Worm   134 ETQNVKVFLPFS--PLQIPRELEQP---SQISPNQLDDIIDYSRCSISSFMPVYV------DIIT 187

  Fly   243 KGYDIDGFLKTTLKQTLGYNAHIVKDPKHACI-----------------YLVLVGEALLEQDLLR 290
            .|.....:| ...::.:   .::|:.|..|||                 .|..||..::.
 Worm   188 SGQSEKEWL-NVFQEVI---PNLVETPDKACIKIHISNGIASPNTTFNSILFNVGSPIIN----- 243

  Fly   291 NNRYAAQEAEHQQPSTPTLENDCPVDMEKLYSLPYWGGDGRNHVLLNLARRDLTSHRTNPLYRQN 355
                ...::.|.|.| .....|.|||:              ||:.:.  :.|||.  ..|..|:|
 Worm   244 ----FQSKSIHVQAS-KIRSFDFPVDV--------------NHIAVE--KVDLTP--LLPFQREN 285

  Fly   356 TMRAIVVQSAFEREQFRPGYDLIVPPILGPPGGDVWQECAEMVPARRKYLLTYQGELRPKQSSLN 420
            .:..||..:......|                     ......|:||..::.
 Worm   286 LISLIVDNTELNFSAF---------------------SSLSAEPSRRPIVIV------------- 316

  Fly   421 PLDAFILEHLADMAKGATQDQFVLQFQCVPATEQQEGDSLPDWTLCGSDSSRRQLLKDSTFSLIL 485
                                      :|     .||..||         ..||||:..|||..:|
 Worm   317 --------------------------KC-----SQENCSL---------ERRRQLIGSSTFCFLL 341

  Fly   486 PPLNGRVSSTLMLARIYEALRSGAVPVILGADELRLPYAETVDWRRTALLLPKARITELHFLLRA 550
            |       |.:.......:|:.|.:|:||...:| ||:.:.:||||....||.||:.|.||::::
 Worm   342 P-------SEMFFQDFLSSLQLGCIPIILSNSQL-LPFQDLIDWRRATYRLPLARLPEAHFIVQS 398

  Fly   551 VQDADLLLLRRQGRLIWERYLSSVQATVDTVIASLRDRLGIPPRPVPSVIAQSVFNSTF-IPLKS 614
            .:.:|::.:||.|||.:|.||:.......:::|:||.:|.||.|.|....|..:|||:| .|..|
 Worm   399 FEISDIIEMRRVGRLFYETYLADRHLLARSLLAALRYKLQIPTREVRRNQAIPLFNSSFTAPKGS 463

  Fly   615 DPPVGLDTEPEESLGPIEPPYPSPAFRRNYTILRMQAKEAWNDWLDPFYLYPQLPFDPALPSEAK 679
            ...|..:.:.|..|||:|....|.::..|:|..::.:.:.||..:.|.|....|.....||:||:
 Worm   464 VVNVQANFDDEYLLGPLESRVESTSYAYNFTEFQLYSYDFWNIIMSPHYTKEFLVNAAELPTEAE 528

  Fly   680 FM-GSHTGFRPIGKGLGGAGKEFGESLGGNYPREQFTIVMLTYEREQVLMDSLGRLYGLPYLHKV 743
            |. .:..|||||..   |:|.||.::||||..|||||:|:|||||:.||..:|.||:.||||:|:
 Worm   529 FFEDTKIGFRPIEP---GSGAEFSKALGGNRQREQFTVVLLTYERDAVLTGALERLHQLPYLNKI 590

  Fly   744 VVVWNS-PKPPLDDLRWPDIGVPVAVLRAPRNSLNNRFLPFDVIETEAVLSVDDDAHLRHDEILF 807
            :||||: .:.|.|  .||.:.:||..:|...|:|||||:|:|.||||||||:|||..|...||:.
 Worm   591 IVVWNNVNRDPPD--TWPSLHIPVEFIRVAENNLNNRFVPWDRIETEAVLSLDDDIDLMQQEIIL 653

  Fly   808 GFRVWREHRDRVVGFPGRYHAWDLGNPNGQWHYNSNYSCELSMVLTGAAFVHKYYLYLYTYHLPQ 872
            .||||||:|||:||||.|:||    .......||||::|::||:||||||:||.||..|||.:|.
 Worm   654 AFRVWRENRDRIVGFPARHHA----RYGDSMFYNSNHTCQMSMILTGAAFIHKNYLTAYTYEMPA 714

  Fly   873 AIRDKVDEYMNCEDIAMNFLVSHITRKPPVKVTSRWTFRCPGCPVSLSEDDTHFQERHKCINFFS 937
            .||:.|:...||||||||:||||:|||||:|.|||||.:||.|..||.::.|||::||:|:..|:
 Worm   715 EIREHVNSIKNCEDIAMNYLVSHLTRKPPIKTTSRWTLKCPTCTESLYKEGTHFEKRHECMRLFT 779

  Fly   938 RVFGYTPLLNTQYRADSILFKTRIPHDKQKCFKYI 972
            :::||.||..:|:||||||||||:|.:.||||||:
 Worm   780 KIYGYNPLKFSQFRADSILFKTRLPQNHQKCFKYV 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
botv	NP_523790.1	CC_brat-like	106..>179	CDD:475168	20/72 (28%)
		Exostosin	224..551	CDD:397245	69/343 (20%)
		Glyco_transf_64	714..953	CDD:430488	132/239 (55%)
rib-2	NP_499368.1	GumC	<49..>162	CDD:442439	34/131 (26%)
		RXYLT1-like	175..399	CDD:473306	69/343 (20%)
		Glyco_transf_64	561..795	CDD:430488	132/239 (55%)