DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18605 and toporsa

DIOPT Version :9

Sequence 1:	NP_001188974.1	Gene:	CG18605 / 37189	FlyBaseID:	FBgn0034411	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_001292484.1	Gene:	toporsa / 324197	ZFINID:	ZDB-GENE-030131-6401	Length:	999	Species:	Danio rerio

Alignment Length:	372	Identity:	75/372 - (20%)
Similarity:	140/372 - (37%)	Gaps:	61/372 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MMPRHMVQWRIYVYANSLYSLPDRET--------------------GDFRGWSPEYFRLNPFEVH 45
            |:.|..|:.|......||.||.|:|.                    |..|..|.|:|:.||..:|
Zfish   149 MIRRLTVRQRRESEGRSLRSLQDQEVVKFRRALYRRGVQVQSVQDGGRTRETSAEFFKRNPACLH 213

  Fly    46 RVMMWVNRDVSVLIRTRKADIFYLYETIKNLLPRLKLDSEEFRKPMIHFFGANTDLFIHELINFA 110
            |::.|:.|:::||.....:.:..:...|..|:.|..||.:..:..:..|..::|:.|:||.::||
Zfish   214 RLVPWLRRELTVLYGAHGSLVNIVQHIIMTLITRHNLDDQAVQHELRPFLLSHTEHFLHEFLSFA 278

  Fly   111 RSP-----YDTLMAY-------ECSTQYRALLDFDNGPTTSAKSRDREFLSTRLHS----FVEFT 159
            |||     ||....|       |.|:...:::......:.|..|..::|.:.|:.|    :.:.|
Zfish   279 RSPFNMEAYDQRAVYDLPRPSGESSSSENSVIAISEDESESLVSGAQDFATPRVTSSQTAWDDET 343

  Fly   160 RRINYDDCGGFEADLELEDEDFGELDDMMMERYGGAPFLMKMDGQLVTARIIPSSQANAPNQGQ- 223
            ...:|.........:.:.|.|   .|..:.|.......:...|.....:.|.|....::.|...
Zfish   344 PGPSYSSERSQVLPVHVRDSD---SDSSVGEAVMPIAAVRHQDHPANPSTIQPEEDHSSSNDEDC 405

  Fly   224 --------VNQQTQSQAQAQAQAQAQVQAQAQAQAQTQAQTQAQALAQAQAQAQVQAQPQAQVQQ 280
                    |.::|....|..:.::.....|..:...:||....:.::.:.|......:|    .:
Zfish   406 VIIGYVKPVAERTPELVQLSSDSENSETEQNASPRNSQAPQHIRFISDSDASPTASQRP----LR 466

  Fly   281 AAAQPAQLLLPQLTQAVIQTQQRAVHQPQQSGQQSGPQ-----HASS 322
            ..|..::    ......||.::.:.:....||.:.|..     |:||
Zfish   467 GPASSSR----SFEDTSIQLRKNSKYDNTFSGSREGSSQSKRIHSSS 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG18605	NP_001188974.1	None
toporsa	NP_001292484.1	RING-HC_Topors	28..67	CDD:319488
		RING-HC finger (C3HC4-type)	28..66	CDD:319488
		RRM	635..>749	CDD:330708
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579331
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003652
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930