Protein Alignment MetRS and MetRS-m

DIOPT Version :10

• Sequence 1: NP_611382.1
• Gene: MetRS / 37177
• FlyBaseID: FBgn0034401
• Length: 1022
• Species: Drosophila melanogaster
• Sequence 2: NP_650348.1
• Gene: MetRS-m / 41733
• FlyBaseID: FBgn0027083
• Length: 582
• Species: Drosophila melanogaster
• Alignment Length: 621
• Identity: 146/621 - (23%)
• Similarity: 236/621 - (38%)
• Gaps: 127/621 - (20%)

  Fly   258 ITSALPYVNNVPHLGNIIGCVLSADIYARYS--RSAGYNTLLICGTDEYGTATENKALAENLTPR 320
            :|:.:.|||..||:|::...|: ||.:.||.  |....:..|..||||:||..:..|....:...
  Fly    22 VTTPIFYVNAAPHIGHLYSAVI-ADAHCRYQRLRYPEQDVRLCTGTDEHGTKIQQAASLHGVPVA 85

  Fly   321 EICDKYFELHNAIYRWFGIGFDYFGRTTTQEQTDIVQEAFKDVLKAGYIITESVEQLLCQKCDRF 385
            :.||...:.:..::|...|..|.|.|||.......|...::.:...|:|.:.:.....|...:.|
  Fly    86 KYCDDISQRYREVFRSASIQQDDFIRTTEDRHKRAVANFWRTLHTRGHIYSAAYSGWYCVSDETF 150

  Fly   386 LADRFVEGTCPHPGCGYEDARGDQCD-KCGKLVNATELIRPRCKVCNSAPVLRSSDQLFIDLPKA 449
            |.|..:.         .::|.|.:.. :.|..|..||                .::.:| .|.:.
  Fly   151 LTDSQLR---------LDEATGTRYSLESGHPVEWTE----------------ETNYMF-RLSQF 189

  Fly   450 EPQLKEWVDKSEGGWTHNAKV-------ITRAWLKEGLKPRCITRD---LKWGIPVPHEGFEKKV 504
            :..::.|| |:|      |:|       |....|.|.|....::|.   :.|.||||.:  :.:.
  Fly   190 QDDVRHWV-KTE------ARVRPAKFEKILLDTLSEPLPDVSVSRPSNRVHWAIPVPDD--DSQT 245

  Fly   505 FYVWFDAPFGYVSMTKRYTKEYQQWWQPAKGTDVELFQFMAKDNVPFHSVVWPSVLLAINKGHTL 569
            .|||.||...|:|......:::...|.||:       |.:.||.:.||.:.|.:.|||  .|...
  Fly   246 VYVWLDALVNYLSSVGYPDEKFSAHWPPAQ-------QVIGKDILKFHGIYWTAFLLA--AGLEP 301

  Fly   570 VSHIMATEYLNYEDGKFSKSRGIGVFGNDAQE----TGIPADVWRFYLASARPEGQDSSFSWNDL 630
            ...:....:...:..|.|||:...|....|.:    .|:     |::|........|.::|....
  Fly   302 PGQLYVHSHWTVDGQKMSKSKHNVVDPLQAAQQYTMEGL-----RYFLLREGVAHSDGNYSHVKA 361

  Fly   631 AARNNSELLNNLGNFVNRALVFCEKNFSSTVPGVITTQDELVLLALINRELRGYINSMEKAK-LR 694
            ....||||.:.|||.::||      :..|..||.|......       ..|...:.|::.|| |:
  Fly   362 QRILNSELADTLGNLLSRA------SAKSLNPGQIYPSPSA-------EHLADLLRSLDVAKRLQ 413

  Fly   695 DGVRHL--------------------LAISRHGNGYMQSQQPWVLLKGT-DDQKTRASTIIGLCV 738
            |.:..|                    :|.....|.:.:|.:||.|..|. |..:.|..|||.:.:
  Fly   414 DSLLQLSERCESHYECNHFHLVADTTMAALHAANNFFESSKPWTLKAGAPDGNQARLETIIAMTM 478

  Fly   739 NIACLLANLLFPYMPTTARTLFGQLNAK-------------QTPLNAEKPLVTLLLPAGHQIGKP 790
            :...|...:|.|.:|..|..|..:|:..             .|..|:...      |||  :|:.
  Fly   479 DALRLSGIVLQPIIPQLANRLLDKLSVPTAQRGWNYLAESFATSPNSSNS------PAG--LGES 535

  Fly   791 APL----FAKLEQSFIDELKGKYGGAQATNDAAHSQ 822
            ..|    .|.|.|..::|...|....|....|..|:
  Fly   536 RQLDGQTSALLFQRILEETSAKEVKEQKPQPAKRSK 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MetRS	NP_611382.1	GST_N_5	1..70	CDD:436537
		GST_C_family	63..164	CDD:470672
		PLN02610	248..>850	CDD:215329	146/621 (24%)
		MetRS_RNA	895..938	CDD:238475
		MetRS_RNA	966..1009	CDD:238475
MetRS-m	NP_650348.1	MetG	21..559	CDD:439913	143/607 (24%)