DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MetRS and AIMP1

DIOPT Version :9

Sequence 1:	NP_611382.1	Gene:	MetRS / 37177	FlyBaseID:	FBgn0034401	Length:	1022	Species:	Drosophila melanogaster
Sequence 2:	NP_610426.2	Gene:	AIMP1 / 35892	FlyBaseID:	FBgn0033351	Length:	323	Species:	Drosophila melanogaster

Alignment Length:	207	Identity:	42/207 - (20%)
Similarity:	72/207 - (34%)	Gaps:	70/207 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   788 GKPAPLFAKLEQSFID--ELKGKYGGAQATNDAAHSQISAADLEKAVQAQADKVRELKASTK--D 848
            |:....||:.:::..|  ::......|:|..::..::||....:...:.:.:.::|..|..|  :
  Fly    17 GQNCSKFARNKRTMADLQQIASNNERAEALINSIEAEISGIQQQLVERQKQELIKENAALAKEVE 81

  Fly   849 KAIWQPEVTKLLDLKKQL------------------EEAKKKTATAAAPAATPAPSNGSQSVQDL 895
            .|:.|....:|.:.|||:                  .||...||..||||..||
  Fly    82 AALAQLVQLELRNGKKQIPVPGARGFCTSAAPVVMPAEAGPATAAPAAPAPKPA----------- 135

  Fly   896 EKAIQEQGDKVRKLKGSTKDKTVWQPEVNILLDLKKQLEAVQKAAKAAPAANAAPAASPAATADA 960
             |..:|:..|.:|                                   |||. .|||:|.|..|.
  Fly   136 -KEPKEKKSKEKK-----------------------------------PAAE-KPAAAPEAPVDV 163

  Fly   961 AKVKALEDKIAQ 972
            .::.....||.:
  Fly   164 GRLDLRVGKIVE 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MetRS	NP_611382.1	GstA	1..175	CDD:223698
		GST_N_family	1..65	CDD:238319
		GST_C_family	63..164	CDD:295467
		PRK12268	254..812	CDD:237029	4/25 (16%)
		MetRS_core	255..625	CDD:173907
		Anticodon_Ia_Met	634..763	CDD:153411
		MetRS_RNA	828..868	CDD:238475	9/59 (15%)
		MetRS_RNA	895..938	CDD:238475	4/42 (10%)
		MetRS_RNA	966..1009	CDD:238475	2/7 (29%)
AIMP1	NP_610426.2	tRNA_bind_EMAP-II_like	161..262	CDD:239198	3/15 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0143
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900